vasculitis Gene Set

Dataset GWASdb SNP-Disease Associations
Category disease or phenotype associations
Type disease
Description A vascular disease that is characterized by inflammation of the blood vessels. (Human Disease Ontology, DOID_865)
External Link http://jjwanglab.org/gwasdb/gwasdb2/gwasdb2/go_trait/DOID:865
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Genes

85 genes associated with the disease vasculitis in GWAS and other genetic association datasets from the GWASdb SNP-Disease Associations dataset.

Symbol Name Standardized Value
HLA-DPB2 major histocompatibility complex, class II, DP beta 2 (pseudogene) 2.11779
HLA-DPB1 major histocompatibility complex, class II, DP beta 1 1.90464
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 1.73436
HLA-B major histocompatibility complex, class I, B 1.5061
PSORS1C1 psoriasis susceptibility 1 candidate 1 1.27447
F8 coagulation factor VIII, procoagulant component 1.25477
IL10 interleukin 10 1.16229
TSC22D1 TSC22 domain family, member 1 1.10764
WNT9B wingless-type MMTV integration site family, member 9B 0.971169
NTN4 netrin 4 0.95603
TMEM164 transmembrane protein 164 0.949336
CTLA4 cytotoxic T-lymphocyte-associated protein 4 0.930169
PRR27 proline rich 27 0.915252
NOX4 NADPH oxidase 4 0.907791
NLGN4X neuroligin 4, X-linked 0.826025
NELL1 NEL-like 1 (chicken) 0.808405
CCHCR1 coiled-coil alpha-helical rod protein 1 0.781126
MAMLD1 mastermind-like domain containing 1 0.77043
DAB1 Dab, reelin signal transducer, homolog 1 (Drosophila) 0.743993
MPDZ multiple PDZ domain protein 0.70813
MICA MHC class I polypeptide-related sequence A 0.699173
MOG myelin oligodendrocyte glycoprotein 0.588989
ERAP1 endoplasmic reticulum aminopeptidase 1 0.570922
C6ORF15 chromosome 6 open reading frame 15 0.553783
FGF12 fibroblast growth factor 12 0.547847
VWF von Willebrand factor 0.529547
ZNRD1-AS1 ZNRD1 antisense RNA 1 0.524306
HCP5 HLA complex P5 (non-protein coding) 0.523346
KLRC4 killer cell lectin-like receptor subfamily C, member 4 0.496271
STAT4 signal transducer and activator of transcription 4 0.496271
PSORS1C2 psoriasis susceptibility 1 candidate 2 0.483161
TFCP2L1 transcription factor CP2-like 1 0.481235
HLA-F-AS1 HLA-F antisense RNA 1 0.475917
MICB MHC class I polypeptide-related sequence B 0.469327
DDR1 discoidin domain receptor tyrosine kinase 1 0.457957
DPCR1 diffuse panbronchiolitis critical region 1 0.455846
DDX39B DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B 0.444153
LTA lymphotoxin alpha 0.432338
HCG18 HLA complex group 18 (non-protein coding) 0.43147
RNF175 ring finger protein 175 0.428153
TRIM26 tripartite motif containing 26 0.427278
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 0.427102
FOXP1 forkhead box P1 0.420482
CLASP2 cytoplasmic linker associated protein 2 0.420191
ATP6V1G2 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2 0.417982
VARS2 valyl-tRNA synthetase 2, mitochondrial 0.417725
ATP6V1G2-DDX39B ATP6V1G2-DDX39B readthrough (NMD candidate) 0.417131
CCDC180 coiled-coil domain containing 180 0.416567
ASTN2 astrotactin 2 0.415733
LACC1 laccase (multicopper oxidoreductase) domain containing 1 0.414264
HLA-F major histocompatibility complex, class I, F 0.413934
SFTA2 surfactant associated 2 0.41379
GPM6A glycoprotein M6A 0.408812
POU5F1 POU class 5 homeobox 1 0.408331
KLRK1 killer cell lectin-like receptor subfamily K, member 1 0.407594
CSMD1 CUB and Sushi multiple domains 1 0.406711
HCG27 HLA complex group 27 (non-protein coding) 0.405421
FBXL2 F-box and leucine-rich repeat protein 2 0.404442
MUC22 mucin 22 0.403622
DOCK4 dedicator of cytokinesis 4 0.401752
UBP1 upstream binding protein 1 (LBP-1a) 0.39874
NSMCE2 non-SMC element 2, MMS21 homolog (S. cerevisiae) 0.398668
MCF2L2 MCF.2 cell line derived transforming sequence-like 2 0.397836
DCC DCC netrin 1 receptor 0.396982
ZC3H13 zinc finger CCCH-type containing 13 0.395827
WDFY4 WDFY family member 4 0.394614
EFCAB11 EF-hand calcium binding domain 11 0.390074
PPP1R10 protein phosphatase 1, regulatory subunit 10 0.38968
MDC1 mediator of DNA-damage checkpoint 1 0.389631
JARID2 jumonji, AT rich interactive domain 2 0.388147
IL1R2 interleukin 1 receptor, type II 0.386259
WWTR1 WW domain containing transcription regulator 1 0.38522
CCDC42 coiled-coil domain containing 42 0.382176
LOC100287329 uncharacterized LOC100287329 0.3785
ACSBG1 acyl-CoA synthetase bubblegum family member 1 0.375884
FXYD5 FXYD domain containing ion transport regulator 5 0.375785
FYCO1 FYVE and coiled-coil domain containing 1 0.374916
ILDR1 immunoglobulin-like domain containing receptor 1 0.374427
CDHR3 cadherin-related family member 3 0.373974
CDSN corneodesmosin 0.372763
TCF19 transcription factor 19 0.371085
CPVL carboxypeptidase, vitellogenic-like 0.370753
UBAC2 UBA domain containing 2 0.337413
RSPO4 R-spondin 4 0.329087
UBASH3B ubiquitin associated and SH3 domain containing B 0.327449