vasculitis Gene Set

Dataset HPO Gene-Disease Associations
Category disease or phenotype associations
Type phenotype
Description A vascular disease that is characterized by inflammation of the blood vessels. (Human Disease Ontology, DOID_865)
External Link http://compbio.charite.de/hpoweb/showterm?id=HP:0002633
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Genes

46 genes associated with the vasculitis phenotype by mapping known disease genes to disease phenotypes from the HPO Gene-Disease Associations dataset.

Symbol Name
C4A complement component 4A (Rodgers blood group)
CASP10 caspase 10, apoptosis-related cysteine peptidase
CD19 CD19 molecule
CD81 CD81 molecule
CFI complement factor I
CR2 complement component (3d/Epstein Barr virus) receptor 2
CTLA4 cytotoxic T-lymphocyte-associated protein 4
DNASE1L3 deoxyribonuclease I-like 3
DOCK8 dedicator of cytokinesis 8
FAS Fas cell surface death receptor
FASLG Fas ligand (TNF superfamily, member 6)
HLA-B major histocompatibility complex, class I, B
HLA-DPB1 major histocompatibility complex, class II, DP beta 1
ICOS inducible T-cell co-stimulator
IFIH1 interferon induced with helicase C domain 1
IGHV4-34 immunoglobulin heavy variable 4-34
IL10 interleukin 10
IL12B interleukin 12B
IL12RB2 interleukin 12 receptor, beta 2
IL23R interleukin 23 receptor
LMX1B LIM homeobox transcription factor 1, beta
LPIN2 lipin 2
LRBA LPS-responsive vesicle trafficking, beach and anchor containing
MEFV Mediterranean fever
MLX MLX, MAX dimerization protein
MS4A1 membrane-spanning 4-domains, subfamily A, member 1
MVK mevalonate kinase
MYD88 myeloid differentiation primary response 88
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NLRP3 NLR family, pyrin domain containing 3
NOD2 nucleotide-binding oligomerization domain containing 2
PNP purine nucleoside phosphorylase
PRKCD protein kinase C, delta
PRTN3 proteinase 3
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
SCN9A sodium channel, voltage gated, type IX alpha subunit
STAT4 signal transducer and activator of transcription 4
TLR4 toll-like receptor 4
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
TNFRSF13C tumor necrosis factor receptor superfamily, member 13C
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12
TREX1 three prime repair exonuclease 1
VPS13A vacuolar protein sorting 13 homolog A (S. cerevisiae)
WAS Wiskott-Aldrich syndrome
WIPF1 WAS/WASL interacting protein family, member 1