vcb complex Gene Set
Dataset
COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category
structural or functional annotations
Type
cellular component
Description
A protein complex that possesses ubiquitin ligase activity; the complex is usually pentameric; for example, in mammals the subunits are pVHL, elongin B, elongin C, cullin-2 (Cul2), and Rbx1. (Gene Ontology , GO_0030891 )
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Genes
23 proteins co-occuring with the vcb complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.
Symbol
Name
Standardized Value
CUL2
cullin 2
1.72432
TCEB1
transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C)
1.61295
TCEB2
transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B)
1.57645
RBX1
ring-box 1, E3 ubiquitin protein ligase
1.37741
VHL
von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
1.3752
USP33
ubiquitin specific peptidase 33
1.09289
DIRC2
disrupted in renal carcinoma 2
0.991714
HIF1A
hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
0.807065
TCEB3
transcription elongation factor B (SIII), polypeptide 3 (110kDa, elongin A)
0.764527
PARK2
parkin RBR E3 ubiquitin protein ligase
0.742769
SKP1
S-phase kinase-associated protein 1
0.64958
CDC34
cell division cycle 34
0.646574
RNF31
ring finger protein 31
0.610355
ERCC5
excision repair cross-complementation group 5
0.574244
ERCC2
excision repair cross-complementation group 2
0.53413
CUL3
cullin 3
0.526341
ERCC4
excision repair cross-complementation group 4
0.521841
XPC
xeroderma pigmentosum, complementation group C
0.455613
XPA
xeroderma pigmentosum, complementation group A
0.418077
CUL1
cullin 1
0.393162
UBE2H
ubiquitin-conjugating enzyme E2H
0.32345
CCT4
chaperonin containing TCP1, subunit 4 (delta)
0.246407
MYC
v-myc avian myelocytomatosis viral oncogene homolog
0.207108