velnacrine-3292 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

194 genes differentially expressed following the velnacrine-3292 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9
ABHD6 abhydrolase domain containing 6
ACPP acid phosphatase, prostate
ADCK4 aarF domain containing kinase 4
ADRB3 adrenoceptor beta 3
ALOX15 arachidonate 15-lipoxygenase
ANKLE2 ankyrin repeat and LEM domain containing 2
APBA2 amyloid beta (A4) precursor protein-binding, family A, member 2
AQP3 aquaporin 3 (Gill blood group)
BAHD1 bromo adjacent homology domain containing 1
BTD biotinidase
C17ORF53 chromosome 17 open reading frame 53
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CADM3 cell adhesion molecule 3
CASP1 caspase 1, apoptosis-related cysteine peptidase
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2
CBX2 chromobox homolog 2
CCL22 chemokine (C-C motif) ligand 22
CD82 CD82 molecule
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1
CNTN1 contactin 1
CREBBP CREB binding protein
CTAGE5 CTAGE family, member 5
CTDSPL CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
CUL9 cullin 9
DGCR8 DGCR8 microprocessor complex subunit
EMID1 EMI domain containing 1
ETV7 ets variant 7
FAM212B family with sequence similarity 212, member B
FANCA Fanconi anemia, complementation group A
FLI1 Fli-1 proto-oncogene, ETS transcription factor
FOXG1 forkhead box G1
FOXN3 forkhead box N3
GHRHR growth hormone releasing hormone receptor
GK glycerol kinase
GNL3L guanine nucleotide binding protein-like 3 (nucleolar)-like
GRK5 G protein-coupled receptor kinase 5
GTF2F2 general transcription factor IIF, polypeptide 2, 30kDa
GULP1 GULP, engulfment adaptor PTB domain containing 1
GUSBP3 glucuronidase, beta pseudogene 3
GYPB glycophorin B (MNS blood group)
HMOX1 heme oxygenase 1
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
JAK2 Janus kinase 2
KCNK12 potassium channel, two pore domain subfamily K, member 12
KDM6B lysine (K)-specific demethylase 6B
KIAA0319L KIAA0319-like
KIF13A kinesin family member 13A
LIG3 ligase III, DNA, ATP-dependent
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LMF2 lipase maturation factor 2
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MMP11 matrix metallopeptidase 11
MOBP myelin-associated oligodendrocyte basic protein
MR1 major histocompatibility complex, class I-related
MST1 macrophage stimulating 1
MYL4 myosin, light chain 4, alkali; atrial, embryonic
N4BP2L2 NEDD4 binding protein 2-like 2
NCAPH2 non-SMC condensin II complex, subunit H2
NCBP2 nuclear cap binding protein subunit 2, 20kDa
NDUFA5 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5
NRF1 nuclear respiratory factor 1
ONECUT2 one cut homeobox 2
PDE9A phosphodiesterase 9A
PEX1 peroxisomal biogenesis factor 1
PLCD1 phospholipase C, delta 1
POLR2J4 polymerase (RNA) II (DNA directed) polypeptide J4, pseudogene
POU4F2 POU class 4 homeobox 2
RABGAP1 RAB GTPase activating protein 1
RHOH ras homolog family member H
ROR2 receptor tyrosine kinase-like orphan receptor 2
RPGRIP1L RPGRIP1-like
RPS4Y1 ribosomal protein S4, Y-linked 1
RWDD3 RWD domain containing 3
S100A11 S100 calcium binding protein A11
S100A8 S100 calcium binding protein A8
SBF1 SET binding factor 1
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein
SIPA1 signal-induced proliferation-associated 1
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SPHK2 sphingosine kinase 2
SZT2 seizure threshold 2 homolog (mouse)
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TRAK1 trafficking protein, kinesin binding 1
TRD T cell receptor delta locus
TSC2 tuberous sclerosis 2
TSNAXIP1 translin-associated factor X interacting protein 1
TTC38 tetratricopeptide repeat domain 38
TTLL4 tubulin tyrosine ligase-like family member 4
TUBA3C tubulin, alpha 3c
WDFY3 WD repeat and FYVE domain containing 3
ZFHX2 zinc finger homeobox 2
ZNF646 zinc finger protein 646

decreased expression

Symbol Name
ALPK1 alpha-kinase 1
ALS2CL ALS2 C-terminal like
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle)
ARNTL2 aryl hydrocarbon receptor nuclear translocator-like 2
ATHL1 ATH1, acid trehalase-like 1 (yeast)
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1
BCL9 B-cell CLL/lymphoma 9
C17ORF80 chromosome 17 open reading frame 80
C1ORF105 chromosome 1 open reading frame 105
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
C2ORF27A chromosome 2 open reading frame 27A
C5 complement component 5
CBX8 chromobox homolog 8
CCDC85C coiled-coil domain containing 85C
CCNT1 cyclin T1
CIC capicua transcriptional repressor
CPPED1 calcineurin-like phosphoesterase domain containing 1
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
EFCAB2 EF-hand calcium binding domain 2
EIF5A eukaryotic translation initiation factor 5A
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5
ERCC5 excision repair cross-complementation group 5
FAM169A family with sequence similarity 169, member A
FAM184A family with sequence similarity 184, member A
FBXO22 F-box protein 22
FBXO31 F-box protein 31
FLCN folliculin
FLT4 fms-related tyrosine kinase 4
FUZ fuzzy planar cell polarity protein
GPATCH2L G patch domain containing 2-like
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
H1F0 H1 histone family, member 0
HIST1H2AI histone cluster 1, H2ai
HIST1H2BJ histone cluster 1, H2bj
HIST1H3B histone cluster 1, H3b
HIST1H4F histone cluster 1, H4f
HPN hepsin
IDI2-AS1 IDI2 antisense RNA 1
IGFBP6 insulin-like growth factor binding protein 6
IL12RB1 interleukin 12 receptor, beta 1
INPP5J inositol polyphosphate-5-phosphatase J
IRF1 interferon regulatory factor 1
KIAA0355 KIAA0355
LHX6 LIM homeobox 6
LOC390998 ribosomal protein L10 pseudogene
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
MAN2C1 mannosidase, alpha, class 2C, member 1
MBTPS2 membrane-bound transcription factor peptidase, site 2
METTL16 methyltransferase like 16
MITF microphthalmia-associated transcription factor
MOCS3 molybdenum cofactor synthesis 3
NME6 NME/NM23 nucleoside diphosphate kinase 6
NPFFR1 neuropeptide FF receptor 1
NRTN neurturin
NXPH4 neurexophilin 4
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)
PARD6B par-6 family cell polarity regulator beta
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PLAC8 placenta-specific 8
PLEKHO2 pleckstrin homology domain containing, family O member 2
PMCHL1 pro-melanin-concentrating hormone-like 1, pseudogene
POMT2 protein-O-mannosyltransferase 2
PPP2R3B protein phosphatase 2, regulatory subunit B'', beta
QPCTL glutaminyl-peptide cyclotransferase-like
RFTN1 raftlin, lipid raft linker 1
RIBC2 RIB43A domain with coiled-coils 2
RIN2 Ras and Rab interactor 2
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
ROM1 retinal outer segment membrane protein 1
RUSC2 RUN and SH3 domain containing 2
SCML2 sex comb on midleg-like 2 (Drosophila)
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SETD8 SET domain containing (lysine methyltransferase) 8
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1
SLN sarcolipin
SOX12 SRY (sex determining region Y)-box 12
STAB2 stabilin 2
STAG3 stromal antigen 3
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TCTN2 tectonic family member 2
TFF2 trefoil factor 2
TH tyrosine hydroxylase
TICAM1 toll-like receptor adaptor molecule 1
TMC7 transmembrane channel-like 7
TMEM209 transmembrane protein 209
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TRIP10 thyroid hormone receptor interactor 10
TRPV1 transient receptor potential cation channel, subfamily V, member 1
VGF VGF nerve growth factor inducible
VIPR1 vasoactive intestinal peptide receptor 1
WDR25 WD repeat domain 25
WDR91 WD repeat domain 91
WLS wntless Wnt ligand secretion mediator
ZNF747 zinc finger protein 747