| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | venetoclax perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the venetoclax_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.107202 |
| MT2A | metallothionein 2A | 0.101021 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0971603 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0878967 |
| S100A10 | S100 calcium binding protein A10 | 0.083175 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0743227 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0742384 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0740549 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.071629 |
| CD44 | CD44 molecule (Indian blood group) | 0.0709343 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0646349 |
| ASPH | aspartate beta-hydroxylase | 0.062885 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0626136 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.0615149 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0587562 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0586361 |
| CDH13 | cadherin 13 | 0.0581285 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0536957 |
| HDAC9 | histone deacetylase 9 | 0.0525697 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.0489529 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | 0.0474981 |
| CENPF | centromere protein F, 350/400kDa | 0.0466793 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0449544 |
| CDK6 | cyclin-dependent kinase 6 | 0.0445703 |
| LDHA | lactate dehydrogenase A | 0.042294 |
| SP100 | SP100 nuclear antigen | 0.0414354 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0381454 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0374851 |
| SEPTIN7 | septin 7 | 0.0353732 |
| EFNA5 | ephrin-A5 | 0.0344455 |
| MYOF | myoferlin | 0.0340749 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0338735 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0337098 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.033025 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0329599 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0327181 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0311076 |
| RIGI | RNA sensor RIG-I | 0.0309249 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0303649 |
| ENO1 | enolase 1, (alpha) | 0.0303344 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0300992 |
| NEK7 | NIMA-related kinase 7 | 0.0296873 |
| TMSB4X | thymosin beta 4, X-linked | 0.0292388 |
| HS3ST3A1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 | 0.0292348 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0291613 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0284259 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0280663 |
| IFITM3 | interferon induced transmembrane protein 3 | 0.0278791 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0274143 |
| TPM3 | tropomyosin 3 | 0.0271774 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0269797 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0264544 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0262533 |
| DIAPH3 | diaphanous-related formin 3 | 0.0258323 |
| RRM2 | ribonucleotide reductase M2 | 0.0258175 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0254077 |
| LNPEP | leucyl/cystinyl aminopeptidase | 0.0252832 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0250592 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0245444 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0242624 |
| SPDL1 | spindle apparatus coiled-coil protein 1 | 0.0240468 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0238739 |
| DSPP | dentin sialophosphoprotein | 0.0238597 |
| SMAD3 | SMAD family member 3 | 0.0237865 |
| MKI67 | marker of proliferation Ki-67 | 0.0237571 |
| MB21D2 | Mab-21 domain containing 2 | 0.0237479 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0236509 |
| ANXA2 | annexin A2 | 0.0235439 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | 0.0232941 |
| CAVIN1 | caveolae associated protein 1 | 0.0226501 |
| VCL | vinculin | 0.0224157 |
| PMP22 | peripheral myelin protein 22 | 0.0222402 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0219684 |
| PRKCE | protein kinase C, epsilon | 0.0215637 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0215122 |
| RPL23 | ribosomal protein L23 | 0.0212837 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0212652 |
| CANX | calnexin | 0.0211894 |
| XPO1 | exportin 1 | 0.0210738 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0210527 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0210163 |
| ANLN | anillin, actin binding protein | 0.0204271 |
| E2F7 | E2F transcription factor 7 | 0.0203316 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0203195 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.0199677 |
| IL6ST | interleukin 6 signal transducer | 0.0199618 |
| TLE4 | transducin-like enhancer of split 4 | 0.0198853 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0198466 |
| TGFBR1 | transforming growth factor, beta receptor 1 | 0.0195985 |
| ITGA6 | integrin, alpha 6 | 0.0195738 |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | 0.0190926 |
| SET | SET nuclear proto-oncogene | 0.0190537 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0190282 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | 0.0189921 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.018959 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.018937 |
| BAZ1B | bromodomain adjacent to zinc finger domain, 1B | 0.0187147 |
| LMO7 | LIM domain 7 | 0.0187 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0185904 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.018525 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.340277 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.321296 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.160492 |
| LOX | lysyl oxidase | -0.138376 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.101554 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0906024 |
| NDRG1 | N-myc downstream regulated 1 | -0.0822381 |
| PODXL | podocalyxin-like | -0.0817931 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0805724 |
| FBN1 | fibrillin 1 | -0.0778948 |
| LOXL2 | lysyl oxidase-like 2 | -0.0775357 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0705095 |
| COL1A2 | collagen, type I, alpha 2 | -0.0653556 |
| VIM | vimentin | -0.0632461 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0624117 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0572078 |
| COL5A1 | collagen, type V, alpha 1 | -0.0571998 |
| ARL15 | ADP-ribosylation factor-like 15 | -0.0568596 |
| TMSB10 | thymosin beta 10 | -0.0567286 |
| PLAT | plasminogen activator, tissue | -0.0545055 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0495026 |
| MYADM | myeloid-associated differentiation marker | -0.0489627 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0487152 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.048651 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0454608 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.04357 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0416556 |
| TENM3 | teneurin transmembrane protein 3 | -0.0414391 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0413226 |
| UBC | ubiquitin C | -0.0384169 |
| FRMD5 | FERM domain containing 5 | -0.0381176 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0364623 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0362438 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0347322 |
| C1D | C1D nuclear receptor corepressor | -0.0340101 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0337957 |
| HLA-B | major histocompatibility complex, class I, B | -0.0336285 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.033417 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.032905 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0314122 |
| AUTS2 | autism susceptibility candidate 2 | -0.0302754 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | -0.0301711 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0297832 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0292705 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0289625 |
| JAZF1 | JAZF zinc finger 1 | -0.0289172 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0288964 |
| COL5A2 | collagen, type V, alpha 2 | -0.0284283 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.028063 |
| INSIG1 | insulin induced gene 1 | -0.0277815 |
| VEGFA | vascular endothelial growth factor A | -0.0269468 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0268438 |
| FTL | ferritin, light polypeptide | -0.0267009 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0264656 |
| NAV1 | neuron navigator 1 | -0.0262992 |
| COPA | coatomer protein complex, subunit alpha | -0.0257566 |
| DPYSL3 | dihydropyrimidinase-like 3 | -0.0250589 |
| NBEAL1 | neurobeachin-like 1 | -0.0249266 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0249101 |
| MAP4 | microtubule-associated protein 4 | -0.024869 |
| L1CAM | L1 cell adhesion molecule | -0.0246456 |
| TPST1 | tyrosylprotein sulfotransferase 1 | -0.0246388 |
| NCOR2 | nuclear receptor corepressor 2 | -0.0245655 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -0.024177 |
| LAMA5 | laminin, alpha 5 | -0.0237407 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0237036 |
| FRMD4A | FERM domain containing 4A | -0.0236031 |
| TAGLN2 | transgelin 2 | -0.0234785 |
| TAPBP | TAP binding protein (tapasin) | -0.023296 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0228514 |
| VAT1 | vesicle amine transport 1 | -0.0224655 |
| MEIS2 | Meis homeobox 2 | -0.0224355 |
| GOLGA4 | golgin A4 | -0.0223409 |
| ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 | -0.0222721 |
| HLA-A | major histocompatibility complex, class I, A | -0.0216431 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0213174 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0212146 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0211331 |
| HDLBP | high density lipoprotein binding protein | -0.0207899 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.020719 |
| LMNA | lamin A/C | -0.0206777 |
| FAM114A1 | family with sequence similarity 114, member A1 | -0.0205911 |
| ACLY | ATP citrate lyase | -0.0205218 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | -0.0204718 |
| GOLGA2 | golgin A2 | -0.0204514 |
| MTSS2 | MTSS I-BAR domain containing 2 | -0.0202886 |
| EGFR | epidermal growth factor receptor | -0.0199994 |
| MTCL1 | microtubule crosslinking factor 1 | -0.0199677 |
| GTF2IRD1 | GTF2I repeat domain containing 1 | -0.0198505 |
| COL18A1 | collagen, type XVIII, alpha 1 | -0.0198225 |
| PEA15 | phosphoprotein enriched in astrocytes 15 | -0.0196701 |
| BSG | basigin (Ok blood group) | -0.0194338 |
| CMIP | c-Maf inducing protein | -0.0193066 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0192538 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | -0.0191692 |
| LRRC49 | leucine rich repeat containing 49 | -0.0190415 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | -0.0188717 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0184272 |
| MAP1B | microtubule-associated protein 1B | -0.0182862 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.018162 |
