| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | venetoclax perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the venetoclax_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | 0.170464 |
| INTS6 | integrator complex subunit 6 | 0.100593 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0991797 |
| RNF213 | ring finger protein 213 | 0.0986545 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | 0.0925173 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | 0.0876134 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0846371 |
| B2M | beta-2-microglobulin | 0.0827315 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0819932 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0794184 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0750048 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0740922 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0682269 |
| MYO1E | myosin IE | 0.062324 |
| SP100 | SP100 nuclear antigen | 0.0623027 |
| SMAD3 | SMAD family member 3 | 0.0605454 |
| DST | dystonin | 0.0586109 |
| TJP1 | tight junction protein 1 | 0.0583125 |
| ASPH | aspartate beta-hydroxylase | 0.0574182 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.0557679 |
| LCN2 | lipocalin 2 | 0.0555436 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0550291 |
| MX2 | MX dynamin-like GTPase 2 | 0.0545769 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0542505 |
| TMC5 | transmembrane channel-like 5 | 0.054245 |
| MX1 | MX dynamin-like GTPase 1 | 0.0528971 |
| KYNU | kynureninase | 0.0527814 |
| IFNGR1 | interferon gamma receptor 1 | 0.0527261 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.0515408 |
| LIMA1 | LIM domain and actin binding 1 | 0.0509335 |
| RIGI | RNA sensor RIG-I | 0.0508712 |
| VMP1 | vacuole membrane protein 1 | 0.0503546 |
| SIPA1L2 | signal-induced proliferation-associated 1 like 2 | 0.0494842 |
| MCU | mitochondrial calcium uniporter | 0.0491072 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0488342 |
| HKDC1 | hexokinase domain containing 1 | 0.0485247 |
| ELOF1 | elongation factor 1 homolog (S. cerevisiae) | 0.0468535 |
| PDZD8 | PDZ domain containing 8 | 0.0467205 |
| CATSPERB | catsper channel auxiliary subunit beta | 0.0461563 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0441724 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0422062 |
| SIK3 | SIK family kinase 3 | 0.0418205 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.0417281 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0415481 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0404831 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0403794 |
| MAP7 | microtubule-associated protein 7 | 0.040279 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0397391 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0384187 |
| EFNB2 | ephrin-B2 | 0.0381563 |
| PLSCR2 | phospholipid scramblase 2 | 0.0372115 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0371054 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0363574 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.0359668 |
| RBM47 | RNA binding motif protein 47 | 0.0356236 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) | 0.0354735 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0346127 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.0339616 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.0337112 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0332301 |
| ZNF292 | zinc finger protein 292 | 0.0329407 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0329155 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0322356 |
| DIP2B | DIP2 disco-interacting protein 2 homolog B (Drosophila) | 0.0312563 |
| YAP1 | Yes-associated protein 1 | 0.0312436 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0306779 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0304857 |
| SPAG9 | sperm associated antigen 9 | 0.0302324 |
| C6ORF132 | chromosome 6 open reading frame 132 | 0.0299711 |
| DIAPH1 | diaphanous-related formin 1 | 0.0298209 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0292437 |
| ETV6 | ets variant 6 | 0.0286447 |
| POF1B | premature ovarian failure, 1B | 0.0279266 |
| APOL1 | apolipoprotein L, 1 | 0.027821 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0277554 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0274159 |
| DSPP | dentin sialophosphoprotein | 0.0274024 |
| TMEM65 | transmembrane protein 65 | 0.0267583 |
| GOLGB1 | golgin B1 | 0.026524 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | 0.0264789 |
| NABP1 | nucleic acid binding protein 1 | 0.0264003 |
| CLOCK | clock circadian regulator | 0.0260335 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.0259564 |
| MT2A | metallothionein 2A | 0.0258971 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0255086 |
| RPL21 | ribosomal protein L21 | 0.025473 |
| UBAP2 | ubiquitin associated protein 2 | 0.0253251 |
| DPP4 | dipeptidyl-peptidase 4 | 0.0251112 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0250156 |
| RND3 | Rho family GTPase 3 | 0.0247416 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0247312 |
| ERBIN | erbb2 interacting protein | 0.0245554 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0245452 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0241941 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0241821 |
| DUSP10 | dual specificity phosphatase 10 | 0.024175 |
| MYO5B | myosin VB | 0.0241723 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.024034 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0238402 |
| ENO1 | enolase 1, (alpha) | 0.0235357 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.1001 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | -0.0912086 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0750087 |
| H1-0 | H1.0 linker histone | -0.0722049 |
| NDRG1 | N-myc downstream regulated 1 | -0.064185 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.063919 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0638307 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0562617 |
| HLA-B | major histocompatibility complex, class I, B | -0.0530347 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0508951 |
| RUNX1 | runt-related transcription factor 1 | -0.0472941 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0380281 |
| EGR1 | early growth response 1 | -0.0375191 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0374558 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.0364442 |
| RNF43 | ring finger protein 43 | -0.0360676 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0360347 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0352342 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.035113 |
| ACTN4 | actinin, alpha 4 | -0.0346319 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0342994 |
| AHNAK | AHNAK nucleoprotein | -0.0326328 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | -0.0325253 |
| GRK3 | G protein-coupled receptor kinase 3 | -0.0324121 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0315698 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | -0.0306402 |
| PTMA | prothymosin, alpha | -0.0304635 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | -0.03012 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0299849 |
| TMPRSS4 | transmembrane protease, serine 4 | -0.0296694 |
| ITGA6 | integrin, alpha 6 | -0.0291172 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0286685 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0286544 |
| NPSR1 | neuropeptide S receptor 1 | -0.0282601 |
| GNAS | GNAS complex locus | -0.0275545 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0274296 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | -0.0273554 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0271612 |
| TXNIP | thioredoxin interacting protein | -0.0268907 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0262954 |
| HDLBP | high density lipoprotein binding protein | -0.0262599 |
| HLA-C | major histocompatibility complex, class I, C | -0.0258535 |
| TMEM62 | transmembrane protein 62 | -0.0254846 |
| DIAPH3 | diaphanous-related formin 3 | -0.0253464 |
| SPATA13 | spermatogenesis associated 13 | -0.0252735 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0250994 |
| RBM39 | RNA binding motif protein 39 | -0.0241747 |
| PTEN | phosphatase and tensin homolog | -0.0231586 |
| CANX | calnexin | -0.0228564 |
| HMGB1 | high mobility group box 1 | -0.0227946 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0227418 |
| IRF1 | interferon regulatory factor 1 | -0.0224252 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0220216 |
| MCTP2 | multiple C2 domains, transmembrane 2 | -0.0216898 |
| RPL35A | ribosomal protein L35a | -0.0216283 |
| RRBP1 | ribosome binding protein 1 | -0.0213565 |
| SQSTM1 | sequestosome 1 | -0.0211258 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0210546 |
| MKI67 | marker of proliferation Ki-67 | -0.0209726 |
| GRAMD2B | GRAM domain containing 2B | -0.0209491 |
| ABHD2 | abhydrolase domain containing 2 | -0.020389 |
| LASP1 | LIM and SH3 protein 1 | -0.020233 |
| AHI1 | Abelson helper integration site 1 | -0.0199379 |
| MPHOSPH8 | M-phase phosphoprotein 8 | -0.0198776 |
| CHD6 | chromodomain helicase DNA binding protein 6 | -0.0198415 |
| ARF1 | ADP-ribosylation factor 1 | -0.0197924 |
| ZNRF3 | zinc and ring finger 3 | -0.0197883 |
| UBAC2 | UBA domain containing 2 | -0.019773 |
| VOPP1 | vesicular, overexpressed in cancer, prosurvival protein 1 | -0.0194789 |
| AGR2 | anterior gradient 2 | -0.0194739 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0194197 |
| TNRC6B | trinucleotide repeat containing 6B | -0.0193917 |
| TMEM263 | transmembrane protein 263 | -0.0192219 |
| BRCA2 | breast cancer 2, early onset | -0.0189252 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0187955 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0187711 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0186556 |
| RPLP1 | ribosomal protein, large, P1 | -0.0185059 |
| CLYBL | citrate lyase beta like | -0.0185002 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0183993 |
| HDAC4 | histone deacetylase 4 | -0.0183581 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0182158 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0181901 |
| ITPKC | inositol-trisphosphate 3-kinase C | -0.0181376 |
| CEP95 | centrosomal protein 95kDa | -0.0180833 |
| CD46 | CD46 molecule, complement regulatory protein | -0.0179516 |
| CCNL1 | cyclin L1 | -0.0179127 |
| RPL34 | ribosomal protein L34 | -0.017813 |
| STK39 | serine threonine kinase 39 | -0.0177564 |
| FOXP1 | forkhead box P1 | -0.0177359 |
| AOPEP | aminopeptidase O (putative) | -0.0177169 |
| TNS4 | tensin 4 | -0.0176917 |
| PRRC2B | proline-rich coiled-coil 2B | -0.0175884 |
| WDR45B | WD repeat domain 45B | -0.0173702 |
| RNF149 | ring finger protein 149 | -0.0173669 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | -0.017314 |
| GSE1 | Gse1 coiled-coil protein | -0.0172868 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0171807 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | -0.0170498 |
| CENPF | centromere protein F, 350/400kDa | -0.016616 |
