| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | venetoclax perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the venetoclax_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYOF | myoferlin | 0.141396 |
| CD44 | CD44 molecule (Indian blood group) | 0.133374 |
| LMO7 | LIM domain 7 | 0.100026 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0976836 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0952204 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.09236 |
| ENO1 | enolase 1, (alpha) | 0.0903997 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | 0.0827553 |
| FOXP1 | forkhead box P1 | 0.0799824 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0792919 |
| ANXA1 | annexin A1 | 0.0775971 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0766765 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0740677 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.069086 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0686902 |
| CLU | clusterin | 0.0667921 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0646987 |
| EXT1 | exostosin glycosyltransferase 1 | 0.062229 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0620641 |
| ASPH | aspartate beta-hydroxylase | 0.0586411 |
| FNDC3B | fibronectin type III domain containing 3B | 0.058114 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0573884 |
| MT2A | metallothionein 2A | 0.0551728 |
| LDHA | lactate dehydrogenase A | 0.0544943 |
| IFITM1 | interferon induced transmembrane protein 1 | 0.0527115 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0525121 |
| DST | dystonin | 0.0522951 |
| NRG1 | neuregulin 1 | 0.0522922 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0520916 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0516889 |
| DOK5 | docking protein 5 | 0.050509 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0490416 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.048793 |
| AOPEP | aminopeptidase O (putative) | 0.0473918 |
| SULF1 | sulfatase 1 | 0.0465542 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0464246 |
| CAMK2D | calcium/calmodulin-dependent protein kinase II delta | 0.0447703 |
| MKI67 | marker of proliferation Ki-67 | 0.0447076 |
| TXNIP | thioredoxin interacting protein | 0.0437747 |
| B2M | beta-2-microglobulin | 0.0432257 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0431493 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0430999 |
| NEK7 | NIMA-related kinase 7 | 0.0417972 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.0413078 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.04109 |
| ANKRD28 | ankyrin repeat domain 28 | 0.040787 |
| PGK1 | phosphoglycerate kinase 1 | 0.0403896 |
| MEF2A | myocyte enhancer factor 2A | 0.0400053 |
| RFX2 | regulatory factor X, 2 (influences HLA class II expression) | 0.0399986 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0398817 |
| DSTN | destrin (actin depolymerizing factor) | 0.0397578 |
| KIAA1217 | KIAA1217 | 0.0395668 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0391815 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0382631 |
| TPR | translocated promoter region, nuclear basket protein | 0.0376916 |
| CENPF | centromere protein F, 350/400kDa | 0.0373676 |
| GOLGB1 | golgin B1 | 0.0373673 |
| EZR | ezrin | 0.0371009 |
| OGA | O-GlcNAcase | 0.0367664 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.036344 |
| FOXO1 | forkhead box O1 | 0.0359567 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0356549 |
| LNPEP | leucyl/cystinyl aminopeptidase | 0.0354456 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0354078 |
| JMJD1C | jumonji domain containing 1C | 0.0350004 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0349956 |
| YBX3 | Y box binding protein 3 | 0.0349858 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0344772 |
| TMOD3 | tropomodulin 3 (ubiquitous) | 0.0340005 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | 0.0339731 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0339101 |
| SLK | STE20-like kinase | 0.0331987 |
| TMSB4X | thymosin beta 4, X-linked | 0.032684 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.0326598 |
| SP100 | SP100 nuclear antigen | 0.0322796 |
| MEF2C | myocyte enhancer factor 2C | 0.0322346 |
| FAM107B | family with sequence similarity 107, member B | 0.0320216 |
| IFITM3 | interferon induced transmembrane protein 3 | 0.0319983 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0317877 |
| SERINC3 | serine incorporator 3 | 0.0317697 |
| TPX2 | TPX2, microtubule-associated | 0.0310643 |
| ARRDC3 | arrestin domain containing 3 | 0.0307942 |
| TNRC6B | trinucleotide repeat containing 6B | 0.0304368 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | 0.0303044 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0301184 |
| PRELID2 | PRELI domain containing 2 | 0.029977 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0297846 |
| TXNRD1 | thioredoxin reductase 1 | 0.029756 |
| CANX | calnexin | 0.0296645 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0296407 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0296078 |
| STC1 | stanniocalcin 1 | 0.0292147 |
| ANLN | anillin, actin binding protein | 0.0290624 |
| RIGI | RNA sensor RIG-I | 0.0286455 |
| FNIP1 | folliculin interacting protein 1 | 0.028599 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0282023 |
| EFNA5 | ephrin-A5 | 0.028071 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0280066 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0279087 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | 0.0278007 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FLNB | filamin B, beta | -0.168912 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.147356 |
| PODXL | podocalyxin-like | -0.106874 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0962381 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.0952841 |
| NDRG1 | N-myc downstream regulated 1 | -0.0930974 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0705644 |
| IGF2 | insulin-like growth factor 2 | -0.0697651 |
| INTS6 | integrator complex subunit 6 | -0.0670225 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0602969 |
| LAMA5 | laminin, alpha 5 | -0.0600037 |
| EGR1 | early growth response 1 | -0.0588861 |
| GRB10 | growth factor receptor-bound protein 10 | -0.054855 |
| ANO1 | anoctamin 1, calcium activated chloride channel | -0.0512052 |
| POTEF | POTE ankyrin domain family, member F | -0.0452462 |
| RCOR1 | REST corepressor 1 | -0.0442053 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0422373 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.0418625 |
| SQSTM1 | sequestosome 1 | -0.0416693 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0411144 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0410044 |
| ADAMTS16 | ADAM metallopeptidase with thrombospondin type 1 motif, 16 | -0.0391972 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0383882 |
| PLS3 | plastin 3 | -0.03571 |
| HMGA2 | high mobility group AT-hook 2 | -0.0356864 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0351546 |
| PLEC | plectin | -0.0342173 |
| GNAS | GNAS complex locus | -0.0337325 |
| MPRIP | myosin phosphatase Rho interacting protein | -0.0331042 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0324105 |
| NCOR2 | nuclear receptor corepressor 2 | -0.031979 |
| HM13 | histocompatibility (minor) 13 | -0.0317575 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0313888 |
| RASAL2 | RAS protein activator like 2 | -0.0309768 |
| FLNA | filamin A, alpha | -0.030902 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0303472 |
| PCDH1 | protocadherin 1 | -0.0297787 |
| FOSL1 | FOS-like antigen 1 | -0.0297272 |
| HMGA1 | high mobility group AT-hook 1 | -0.0291752 |
| DUSP5 | dual specificity phosphatase 5 | -0.0288693 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | -0.028387 |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) | -0.028141 |
| TINAGL1 | tubulointerstitial nephritis antigen-like 1 | -0.0281194 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.0277049 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | -0.0275495 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.0268825 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | -0.0268804 |
| CSMD2 | CUB and Sushi multiple domains 2 | -0.0267109 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | -0.0263771 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | -0.026364 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0258819 |
| HLA-B | major histocompatibility complex, class I, B | -0.0253749 |
| ACTN4 | actinin, alpha 4 | -0.0249746 |
| SULF2 | sulfatase 2 | -0.0246906 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0246021 |
| BCL2L1 | BCL2-like 1 | -0.0245042 |
| THBD | thrombomodulin | -0.0240814 |
| PLXNA2 | plexin A2 | -0.0238245 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -0.0237379 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0232603 |
| CLIC4 | chloride intracellular channel 4 | -0.0229368 |
| LUZP1 | leucine zipper protein 1 | -0.0228758 |
| LAMC2 | laminin, gamma 2 | -0.0224453 |
| CPEB2 | cytoplasmic polyadenylation element binding protein 2 | -0.0224163 |
| CMIP | c-Maf inducing protein | -0.0219865 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0219202 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0218646 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0215674 |
| KIAA1671 | KIAA1671 | -0.0214086 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.02137 |
| FTL | ferritin, light polypeptide | -0.0213233 |
| EGFR | epidermal growth factor receptor | -0.0213106 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | -0.0213084 |
| EFHD2 | EF-hand domain family, member D2 | -0.0213084 |
| LDLR | low density lipoprotein receptor | -0.0207075 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | -0.0205258 |
| CORO2A | coronin, actin binding protein, 2A | -0.0203422 |
| ACTN1 | actinin, alpha 1 | -0.0202905 |
| RPL37A | ribosomal protein L37a | -0.0199493 |
| EPHA2 | EPH receptor A2 | -0.0194114 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0193685 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0193037 |
| SERTAD2 | SERTA domain containing 2 | -0.0192231 |
| NRCAM | neuronal cell adhesion molecule | -0.0190054 |
| ITGB4 | integrin, beta 4 | -0.0189912 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0189729 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A | -0.0188609 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0183667 |
| NECTIN1 | nectin cell adhesion molecule 1 | -0.0181244 |
| HLA-A | major histocompatibility complex, class I, A | -0.0180773 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0179849 |
| FRAS1 | Fraser extracellular matrix complex subunit 1 | -0.0178322 |
| JUN | jun proto-oncogene | -0.0178257 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0178186 |
| SPAG9 | sperm associated antigen 9 | -0.0177831 |
| LAMB3 | laminin, beta 3 | -0.017749 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | -0.0177084 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0176902 |
| LRRC8A | leucine rich repeat containing 8 family, member A | -0.017618 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0173119 |
