| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | venetoclax perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the venetoclax_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0580704 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0424947 |
| SMAD3 | SMAD family member 3 | 0.0415182 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0380211 |
| PRELID2 | PRELI domain containing 2 | 0.0375255 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0362609 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0359325 |
| NAV2 | neuron navigator 2 | 0.035252 |
| ZNF638 | zinc finger protein 638 | 0.0327713 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0326183 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0316443 |
| INTS6 | integrator complex subunit 6 | 0.0313769 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0305556 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.028942 |
| HDAC9 | histone deacetylase 9 | 0.0279663 |
| RAD51B | RAD51 paralog B | 0.0276064 |
| EFNA5 | ephrin-A5 | 0.026435 |
| KYNU | kynureninase | 0.0258505 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0251362 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.0243615 |
| DST | dystonin | 0.0243358 |
| ASPH | aspartate beta-hydroxylase | 0.0238177 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0236678 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0236468 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0225513 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0220098 |
| IFI44L | interferon-induced protein 44-like | 0.0218509 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0214987 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0210441 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0205964 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | 0.0196195 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0195902 |
| FAM13A | family with sequence similarity 13, member A | 0.0193467 |
| ANO6 | anoctamin 6 | 0.0192158 |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 | 0.0190258 |
| EGFR | epidermal growth factor receptor | 0.0188128 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0177875 |
| LRRC49 | leucine rich repeat containing 49 | 0.017143 |
| RUNX1 | runt-related transcription factor 1 | 0.0170872 |
| PTPRB | protein tyrosine phosphatase, receptor type, B | 0.0170202 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0167764 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0166856 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0166006 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0163435 |
| UTRN | utrophin | 0.0162934 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0162403 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0160448 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0158658 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.015839 |
| ATXN1 | ataxin 1 | 0.0153845 |
| NEBL | nebulette | 0.015167 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0148107 |
| WWOX | WW domain containing oxidoreductase | 0.0145835 |
| CADPS2 | Ca++-dependent secretion activator 2 | 0.0143861 |
| PHF3 | PHD finger protein 3 | 0.0138926 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0138923 |
| RARB | retinoic acid receptor, beta | 0.0138672 |
| FNIP1 | folliculin interacting protein 1 | 0.0136601 |
| TAF4B | TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa | 0.0132707 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0132458 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0131494 |
| LRP1B | low density lipoprotein receptor-related protein 1B | 0.0130846 |
| LGALS12 | lectin, galactoside-binding, soluble, 12 | 0.0130559 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0129276 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0128132 |
| FER | fer (fps/fes related) tyrosine kinase | 0.0127251 |
| MIPOL1 | mirror-image polydactyly 1 | 0.0124076 |
| KCTD16 | potassium channel tetramerization domain containing 16 | 0.0122986 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0121779 |
| SKAP2 | src kinase associated phosphoprotein 2 | 0.0121754 |
| KSR1 | kinase suppressor of ras 1 | 0.0121559 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.012087 |
| METTL15 | methyltransferase like 15 | 0.0120463 |
| PARD3B | par-3 family cell polarity regulator beta | 0.0120373 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0120215 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0119331 |
| FBXL13 | F-box and leucine-rich repeat protein 13 | 0.0119004 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.0117401 |
| GPHN | gephyrin | 0.0117077 |
| AADAC | arylacetamide deacetylase | 0.0116151 |
| EXOC4 | exocyst complex component 4 | 0.0116104 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0115205 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | 0.0114655 |
| GPR176 | G protein-coupled receptor 176 | 0.0114538 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0113435 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | 0.0112534 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.011095 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0109959 |
| MYOF | myoferlin | 0.0109662 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | 0.0109153 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0109043 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.010897 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0108398 |
| PCDH7 | protocadherin 7 | 0.0108046 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0106237 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0105521 |
| FHIT | fragile histidine triad | 0.0105016 |
| BBS9 | Bardet-Biedl syndrome 9 | 0.0104399 |
| SUMF1 | sulfatase modifying factor 1 | 0.0103979 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0103462 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.238171 |
| TMSB10 | thymosin beta 10 | -0.218619 |
| VIM | vimentin | -0.20921 |
| FTL | ferritin, light polypeptide | -0.136214 |
| FN1 | fibronectin 1 | -0.111682 |
| PTMA | prothymosin, alpha | -0.10763 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0983687 |
| STC1 | stanniocalcin 1 | -0.0971698 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0925281 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0868067 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0823933 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0762138 |
| S100A6 | S100 calcium binding protein A6 | -0.073204 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.068003 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0655103 |
| RPLP1 | ribosomal protein, large, P1 | -0.0642029 |
| LOX | lysyl oxidase | -0.0638911 |
| RPL35A | ribosomal protein L35a | -0.0637184 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0636662 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0634226 |
| CD44 | CD44 molecule (Indian blood group) | -0.0630237 |
| RPS19 | ribosomal protein S19 | -0.0614681 |
| GLCCI1 | glucocorticoid induced 1 | -0.0611628 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0597786 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0571738 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0564597 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0547603 |
| RPS21 | ribosomal protein S21 | -0.0523343 |
| NRP1 | neuropilin 1 | -0.0507546 |
| RPS8 | ribosomal protein S8 | -0.0503629 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0502908 |
| MT2A | metallothionein 2A | -0.0495477 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0492604 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0491637 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.048854 |
| RPL37A | ribosomal protein L37a | -0.0480514 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0477299 |
| RPLP2 | ribosomal protein, large, P2 | -0.0476893 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0474873 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0474357 |
| CLMP | CXADR-like membrane protein | -0.0474356 |
| B2M | beta-2-microglobulin | -0.0459868 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0457227 |
| IER3 | immediate early response 3 | -0.0455367 |
| RPL34 | ribosomal protein L34 | -0.0455338 |
| OSMR | oncostatin M receptor | -0.0439973 |
| RPS6 | ribosomal protein S6 | -0.0424368 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0419431 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0418081 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0417051 |
| RPL23 | ribosomal protein L23 | -0.0405975 |
| NDRG1 | N-myc downstream regulated 1 | -0.0404272 |
| RPS12 | ribosomal protein S12 | -0.0401952 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0401383 |
| UBC | ubiquitin C | -0.039883 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0395322 |
| NPC1 | Niemann-Pick disease, type C1 | -0.039488 |
| RPS29 | ribosomal protein S29 | -0.0387839 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0384393 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0382312 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0381716 |
| RPL31 | ribosomal protein L31 | -0.0379262 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0377181 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0376518 |
| SNX9 | sorting nexin 9 | -0.0376432 |
| TMSB4X | thymosin beta 4, X-linked | -0.0362679 |
| MTSS1 | metastasis suppressor 1 | -0.0362415 |
| RPS24 | ribosomal protein S24 | -0.0361698 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0358007 |
| RPL36 | ribosomal protein L36 | -0.0357537 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0354544 |
| RAB27B | RAB27B, member RAS oncogene family | -0.0354434 |
| RPS13 | ribosomal protein S13 | -0.0351236 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0345606 |
| EGR1 | early growth response 1 | -0.0344567 |
| AHNAK | AHNAK nucleoprotein | -0.0342414 |
| HLA-B | major histocompatibility complex, class I, B | -0.0342187 |
| RPS3 | ribosomal protein S3 | -0.0340953 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.033985 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0333743 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0333006 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.033222 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0331092 |
| HMGA1 | high mobility group AT-hook 1 | -0.032922 |
| GNAS | GNAS complex locus | -0.0327751 |
| CDH13 | cadherin 13 | -0.03261 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.0325498 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0324109 |
| NUMB | numb homolog (Drosophila) | -0.031578 |
| HMGA2 | high mobility group AT-hook 2 | -0.0314463 |
| RPL12 | ribosomal protein L12 | -0.0309176 |
| RPS25 | ribosomal protein S25 | -0.0308872 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0306468 |
| RPL32 | ribosomal protein L32 | -0.0304736 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0302603 |
| CALR | calreticulin | -0.0300358 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0298631 |
| RPS11 | ribosomal protein S11 | -0.0297071 |
| RPL9 | ribosomal protein L9 | -0.0295502 |
| ACTG1 | actin gamma 1 | -0.029378 |
