| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | venetoclax perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the venetoclax_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TXNRD1 | thioredoxin reductase 1 | 0.102996 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0929395 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0892706 |
| KYNU | kynureninase | 0.0888691 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.0778036 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0740471 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0732928 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0659411 |
| LAMB3 | laminin, beta 3 | 0.0616471 |
| RIGI | RNA sensor RIG-I | 0.0606285 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.059845 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0566115 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0565794 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0559236 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0551651 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.0550215 |
| KRT17 | keratin 17, type I | 0.0546986 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0532172 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0531309 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0513562 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0512625 |
| CANX | calnexin | 0.0506308 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0499861 |
| LYN | LYN proto-oncogene, Src family tyrosine kinase | 0.0488654 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0485259 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0484429 |
| USP34 | ubiquitin specific peptidase 34 | 0.0484292 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0479937 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0474073 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0471829 |
| ZNF638 | zinc finger protein 638 | 0.0470221 |
| ASPH | aspartate beta-hydroxylase | 0.0467047 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0434256 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0430934 |
| SLK | STE20-like kinase | 0.042862 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0427079 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0408988 |
| RPS12 | ribosomal protein S12 | 0.040647 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0403742 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0403165 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.040093 |
| GPHN | gephyrin | 0.0400151 |
| EFNA5 | ephrin-A5 | 0.0397095 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0397088 |
| CTBP2 | C-terminal binding protein 2 | 0.0395887 |
| INHBA | inhibin, beta A | 0.0385108 |
| MAN2A1 | mannosidase, alpha, class 2A, member 1 | 0.0379316 |
| IGF2 | insulin-like growth factor 2 | 0.0378719 |
| MYOF | myoferlin | 0.0378438 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.0377101 |
| GLCCI1 | glucocorticoid induced 1 | 0.0374551 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | 0.0374457 |
| RPS25 | ribosomal protein S25 | 0.037444 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0372995 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0371914 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.037116 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0367562 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0363465 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0362974 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0362125 |
| OGA | O-GlcNAcase | 0.0361302 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.0360423 |
| FLNB | filamin B, beta | 0.0356492 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0355008 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0354325 |
| IWS1 | IWS1 homolog (S. cerevisiae) | 0.0351392 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0350009 |
| OASL | 2'-5'-oligoadenylate synthetase-like | 0.0347988 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0345875 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0345015 |
| ABLIM1 | actin binding LIM protein 1 | 0.0344284 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.0343144 |
| TMEM87A | transmembrane protein 87A | 0.0342565 |
| SP100 | SP100 nuclear antigen | 0.0341241 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0341114 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0338013 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0337944 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.033744 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0333338 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.033134 |
| EXOC6B | exocyst complex component 6B | 0.032832 |
| HLA-B | major histocompatibility complex, class I, B | 0.0326801 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0325333 |
| KIF5B | kinesin family member 5B | 0.0324942 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0316952 |
| CREBBP | CREB binding protein | 0.0314 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0312976 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0312732 |
| BAZ1B | bromodomain adjacent to zinc finger domain, 1B | 0.0312321 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.0308109 |
| MYO5B | myosin VB | 0.0305701 |
| PLEKHA1 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 | 0.0304908 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0302834 |
| HLA-A | major histocompatibility complex, class I, A | 0.0302587 |
| UBE2K | ubiquitin-conjugating enzyme E2K | 0.0300344 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0300107 |
| PCNX1 | pecanex 1 | 0.0296253 |
| SMARCA5 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 | 0.0295999 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | 0.0294414 |
| PCBP2 | poly(rC) binding protein 2 | 0.0293653 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.171248 |
| ANXA2 | annexin A2 | -0.0944067 |
| FN1 | fibronectin 1 | -0.0782004 |
| GPC6 | glypican 6 | -0.0767109 |
| VMP1 | vacuole membrane protein 1 | -0.0737021 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0698481 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | -0.0681881 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0607151 |
| PDE10A | phosphodiesterase 10A | -0.0601837 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0596836 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0595654 |
| MCL1 | myeloid cell leukemia 1 | -0.0545818 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0534424 |
| MT2A | metallothionein 2A | -0.052586 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0506178 |
| RORA | RAR-related orphan receptor A | -0.050522 |
| FTL | ferritin, light polypeptide | -0.0494974 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0459789 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0455341 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.0452181 |
| MSI2 | musashi RNA-binding protein 2 | -0.0448826 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0443647 |
| TAOK3 | TAO kinase 3 | -0.043558 |
| S100A10 | S100 calcium binding protein A10 | -0.0431941 |
| TC2N | tandem C2 domains, nuclear | -0.0427111 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0425067 |
| SETD5 | SET domain containing 5 | -0.0424258 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | -0.0424116 |
| PRKCA | protein kinase C, alpha | -0.0423848 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.0413851 |
| NDRG1 | N-myc downstream regulated 1 | -0.0408717 |
| FUS | FUS RNA binding protein | -0.0402313 |
| DGKD | diacylglycerol kinase, delta 130kDa | -0.0392614 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0391473 |
| SETX | senataxin | -0.039101 |
| OXSR1 | oxidative stress responsive 1 | -0.0386709 |
| ARF1 | ADP-ribosylation factor 1 | -0.0385486 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0385036 |
| NF1 | neurofibromin 1 | -0.0381033 |
| PTK2 | protein tyrosine kinase 2 | -0.0380638 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0364519 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | -0.0361052 |
| CERS6 | ceramide synthase 6 | -0.0360555 |
| ZNF217 | zinc finger protein 217 | -0.0357739 |
| AFF1 | AF4/FMR2 family, member 1 | -0.0355051 |
| MYO6 | myosin VI | -0.0350357 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | -0.034935 |
| TMSB10 | thymosin beta 10 | -0.0348964 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0347492 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0347373 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | -0.0346132 |
| OXR1 | oxidation resistance 1 | -0.0345259 |
| TJP2 | tight junction protein 2 | -0.0345143 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0344091 |
| NUMB | numb homolog (Drosophila) | -0.0340191 |
| C1GALT1 | core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 | -0.0335102 |
| KIRREL1 | kirre like nephrin family adhesion molecule 1 | -0.0334119 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0333987 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0332153 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0330525 |
| MBD4 | methyl-CpG binding domain protein 4 | -0.0329513 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | -0.0329465 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0328979 |
| SDCBP2 | syndecan binding protein (syntenin) 2 | -0.0327418 |
| LRCH3 | leucine-rich repeats and calponin homology (CH) domain containing 3 | -0.0326215 |
| KLF6 | Kruppel-like factor 6 | -0.0326166 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.032346 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0321135 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0314017 |
| KDM4B | lysine (K)-specific demethylase 4B | -0.031399 |
| ANXA1 | annexin A1 | -0.031312 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0311816 |
| GPR107 | G protein-coupled receptor 107 | -0.0311124 |
| USP53 | ubiquitin specific peptidase 53 | -0.0310096 |
| NPAS3 | neuronal PAS domain protein 3 | -0.0309593 |
| DENND2C | DENN/MADD domain containing 2C | -0.0308762 |
| NRG1 | neuregulin 1 | -0.0304581 |
| NCOA3 | nuclear receptor coactivator 3 | -0.0303601 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | -0.0302318 |
| SEPTIN7 | septin 7 | -0.0301748 |
| ACTG1 | actin gamma 1 | -0.0297388 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -0.0297144 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0296101 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0296075 |
| ATOSA | atos homolog A | -0.0295421 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | -0.0294755 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0292656 |
| LMO7 | LIM domain 7 | -0.0292516 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0290726 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | -0.029003 |
| SYNGAP1 | synaptic Ras GTPase activating protein 1 | -0.0288223 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | -0.0285806 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | -0.0285258 |
| ZNF609 | zinc finger protein 609 | -0.0281668 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 | -0.0278316 |
| WDR26 | WD repeat domain 26 | -0.0277129 |
| AFDN | afadin, adherens junction formation factor | -0.0275479 |
| COG6 | component of oligomeric golgi complex 6 | -0.0273271 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0272674 |
| RPS4X | ribosomal protein S4, X-linked | -0.0271007 |
