| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | venetoclax perturbation in NCI-H2347 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the venetoclax_NCI-H2347 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SAMD4A | sterile alpha motif domain containing 4A | 0.122046 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.120627 |
| EXT1 | exostosin glycosyltransferase 1 | 0.116457 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.116385 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.110108 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.103783 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0836238 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0815289 |
| EFNA5 | ephrin-A5 | 0.0735011 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0704715 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0702904 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.068466 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0681514 |
| GOLGB1 | golgin B1 | 0.0642903 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.063565 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0575075 |
| DSPP | dentin sialophosphoprotein | 0.056987 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0569295 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0567397 |
| ENO1 | enolase 1, (alpha) | 0.0550492 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0522949 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.0512142 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0505648 |
| MYO6 | myosin VI | 0.0491578 |
| NAV2 | neuron navigator 2 | 0.0491177 |
| CANX | calnexin | 0.0476869 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0475939 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0475118 |
| RNF213 | ring finger protein 213 | 0.047112 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.0469035 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0464685 |
| FBXO32 | F-box protein 32 | 0.0463105 |
| ERBIN | erbb2 interacting protein | 0.0456886 |
| VCL | vinculin | 0.045321 |
| MYO1E | myosin IE | 0.0437977 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0434557 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0431594 |
| MX1 | MX dynamin-like GTPase 1 | 0.0431085 |
| MYOF | myoferlin | 0.042948 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0417181 |
| FNIP1 | folliculin interacting protein 1 | 0.0415701 |
| PLSCR1 | phospholipid scramblase 1 | 0.0412347 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0405759 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0398079 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0394554 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0393249 |
| ARHGAP20 | Rho GTPase activating protein 20 | 0.038657 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0380559 |
| LDHA | lactate dehydrogenase A | 0.0377511 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0376693 |
| SP100 | SP100 nuclear antigen | 0.0371866 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | 0.0371808 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0371453 |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 | 0.0369759 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0363461 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0362731 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0361503 |
| RAD51B | RAD51 paralog B | 0.0360294 |
| CD109 | CD109 molecule | 0.0359938 |
| PGBD5 | piggyBac transposable element derived 5 | 0.0358296 |
| FAM13A | family with sequence similarity 13, member A | 0.0357229 |
| PALLD | palladin, cytoskeletal associated protein | 0.0352487 |
| DST | dystonin | 0.0350098 |
| SCFD1 | sec1 family domain containing 1 | 0.0347736 |
| CEP350 | centrosomal protein 350kDa | 0.0347681 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0347085 |
| RIGI | RNA sensor RIG-I | 0.0343367 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0341117 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0339741 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.033465 |
| ETV6 | ets variant 6 | 0.0333657 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0332151 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | 0.0331071 |
| MX2 | MX dynamin-like GTPase 2 | 0.0313633 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0312981 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0312376 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0305501 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | 0.0304469 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | 0.0303916 |
| TXNIP | thioredoxin interacting protein | 0.0302927 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0300416 |
| TMF1 | TATA element modulatory factor 1 | 0.0296924 |
| MAP3K13 | mitogen-activated protein kinase kinase kinase 13 | 0.0296325 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.029591 |
| INTS6 | integrator complex subunit 6 | 0.0294512 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.029313 |
| RAB10 | RAB10, member RAS oncogene family | 0.0289938 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0288797 |
| COPB1 | coatomer protein complex, subunit beta 1 | 0.028842 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0288177 |
| SQSTM1 | sequestosome 1 | 0.0285411 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.0284301 |
| PTK2 | protein tyrosine kinase 2 | 0.0283993 |
| ARRDC3 | arrestin domain containing 3 | 0.0283831 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0283407 |
| SAMD12 | sterile alpha motif domain containing 12 | 0.0281332 |
| RAI14 | retinoic acid induced 14 | 0.0279855 |
| ATXN1 | ataxin 1 | 0.02795 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0278742 |
| PHF3 | PHD finger protein 3 | 0.0278624 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.156093 |
| NDRG1 | N-myc downstream regulated 1 | -0.140424 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.132191 |
| HMGA1 | high mobility group AT-hook 1 | -0.0947267 |
| ACTG1 | actin gamma 1 | -0.0792304 |
| FTL | ferritin, light polypeptide | -0.0486372 |
| TMSB10 | thymosin beta 10 | -0.0474514 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0434708 |
| RPL35A | ribosomal protein L35a | -0.0429149 |
| POTEF | POTE ankyrin domain family, member F | -0.0419704 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.041487 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0392712 |
| FAM3C | family with sequence similarity 3, member C | -0.0368164 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0362873 |
| S100A6 | S100 calcium binding protein A6 | -0.0309683 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0297665 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0292616 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0272485 |
| USP3 | ubiquitin specific peptidase 3 | -0.0265043 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0264598 |
| FAM162A | family with sequence similarity 162, member A | -0.02598 |
| PTMA | prothymosin, alpha | -0.025775 |
| FOSL1 | FOS-like antigen 1 | -0.0257338 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0255496 |
| RPL34 | ribosomal protein L34 | -0.0251539 |
| MT2A | metallothionein 2A | -0.0250845 |
| TFG | TRK-fused gene | -0.0242139 |
| CCNL1 | cyclin L1 | -0.0239624 |
| RPS19 | ribosomal protein S19 | -0.0235884 |
| AREG | amphiregulin | -0.0217138 |
| RPL8 | ribosomal protein L8 | -0.0215428 |
| CCND1 | cyclin D1 | -0.0211028 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0210581 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0207187 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0202163 |
| RPL28 | ribosomal protein L28 | -0.0200422 |
| TOP1 | topoisomerase (DNA) I | -0.0197903 |
| MSMO1 | methylsterol monooxygenase 1 | -0.0194354 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | -0.0194281 |
| G0S2 | G0/G1 switch 2 | -0.0192234 |
| FLNA | filamin A, alpha | -0.0190007 |
| LAMB3 | laminin, beta 3 | -0.0188772 |
| RNF145 | ring finger protein 145 | -0.0188642 |
| PKM | pyruvate kinase, muscle | -0.0181978 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0177118 |
| GNAS | GNAS complex locus | -0.0175481 |
| RPS29 | ribosomal protein S29 | -0.0174955 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.017366 |
| NUP58 | nucleoporin 58 | -0.0170456 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0169296 |
| RTN4 | reticulon 4 | -0.0168125 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0166982 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | -0.0163597 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0163497 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0162014 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | -0.0161988 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0160672 |
| CRABP2 | cellular retinoic acid binding protein 2 | -0.0158037 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0156237 |
| PLEC | plectin | -0.0155221 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0154582 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0152714 |
| TRA2B | transformer 2 beta homolog (Drosophila) | -0.0151991 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0149566 |
| NDFIP1 | Nedd4 family interacting protein 1 | -0.0148506 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -0.0148425 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0147395 |
| RPL5 | ribosomal protein L5 | -0.0147142 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | -0.014426 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0143577 |
| CLDN4 | claudin 4 | -0.0142639 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0140714 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.0139646 |
| CCNI | cyclin I | -0.0139283 |
| RPL36 | ribosomal protein L36 | -0.0138344 |
| MXD1 | MAX dimerization protein 1 | -0.0137477 |
| PHLDA2 | pleckstrin homology-like domain, family A, member 2 | -0.0136243 |
| RPS23 | ribosomal protein S23 | -0.0136232 |
| PABPN1 | poly(A) binding protein, nuclear 1 | -0.0136127 |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 | -0.0135929 |
| RPS21 | ribosomal protein S21 | -0.0135164 |
| RPLP2 | ribosomal protein, large, P2 | -0.0135071 |
| PFN1 | profilin 1 | -0.0133531 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | -0.0131589 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0130296 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0129989 |
| RPS5 | ribosomal protein S5 | -0.0129432 |
| CTSD | cathepsin D | -0.0127256 |
| CHMP2B | charged multivesicular body protein 2B | -0.0126467 |
| SREK1IP1 | SREK1-interacting protein 1 | -0.012645 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0125957 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0125918 |
| RPS8 | ribosomal protein S8 | -0.0125094 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | -0.0124298 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0123959 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0123282 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | -0.012258 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | -0.0122143 |
| RPL9 | ribosomal protein L9 | -0.0121305 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.012073 |
