| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | venetoclax perturbation in NCI-H596 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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197 genes differentially expressed following the venetoclax_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.154133 |
| ASPH | aspartate beta-hydroxylase | 0.127361 |
| INTS6 | integrator complex subunit 6 | 0.0867663 |
| RPL37A | ribosomal protein L37a | 0.0797862 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0791667 |
| PTMA | prothymosin, alpha | 0.0754831 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0716689 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0716117 |
| PRELID2 | PRELI domain containing 2 | 0.0655183 |
| TXNRD1 | thioredoxin reductase 1 | 0.0627266 |
| RPS12 | ribosomal protein S12 | 0.0596277 |
| EFNA5 | ephrin-A5 | 0.0574602 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0558908 |
| RPLP1 | ribosomal protein, large, P1 | 0.0541163 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0536002 |
| GOLGB1 | golgin B1 | 0.0529182 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0513166 |
| GPHN | gephyrin | 0.0505596 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0476809 |
| FRMD5 | FERM domain containing 5 | 0.0473089 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0471179 |
| FTL | ferritin, light polypeptide | 0.0461113 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0460727 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0456538 |
| RAD51B | RAD51 paralog B | 0.0445894 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | 0.0436542 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0435293 |
| RPLP2 | ribosomal protein, large, P2 | 0.0433396 |
| MT2A | metallothionein 2A | 0.0430902 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0424254 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0422053 |
| RPL26 | ribosomal protein L26 | 0.0419664 |
| PCBP2 | poly(rC) binding protein 2 | 0.0419015 |
| RPS14 | ribosomal protein S14 | 0.0413465 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0394348 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0392966 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0386914 |
| RPS5 | ribosomal protein S5 | 0.0376806 |
| CANX | calnexin | 0.0374384 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0373479 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0362172 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0357831 |
| RPS13 | ribosomal protein S13 | 0.0356707 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0348305 |
| ATXN1 | ataxin 1 | 0.0347435 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0340482 |
| SMYD3 | SET and MYND domain containing 3 | 0.0331019 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0330231 |
| AK1 | adenylate kinase 1 | 0.0328422 |
| CARD16 | caspase recruitment domain family, member 16 | 0.0323462 |
| FHIT | fragile histidine triad | 0.0321887 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.031806 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0316855 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0316298 |
| MYOF | myoferlin | 0.0315807 |
| RPS29 | ribosomal protein S29 | 0.0310168 |
| FN1 | fibronectin 1 | 0.0308446 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0306649 |
| PCNX4 | pecanex 4 | 0.030616 |
| EXOC4 | exocyst complex component 4 | 0.0305997 |
| RPL37 | ribosomal protein L37 | 0.0302162 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0297304 |
| KYNU | kynureninase | 0.0296779 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0294552 |
| LMO7 | LIM domain 7 | 0.0292719 |
| RPL27A | ribosomal protein L27a | 0.0286157 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0284154 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0280762 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0278645 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0278268 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0277529 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0276351 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0269131 |
| RPL30 | ribosomal protein L30 | 0.0268899 |
| UBE2D2 | ubiquitin-conjugating enzyme E2D 2 | 0.0267034 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0266832 |
| RPS6 | ribosomal protein S6 | 0.0263971 |
| RPL9 | ribosomal protein L9 | 0.0260987 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.0254605 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | 0.0254549 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.025426 |
| RPS27 | ribosomal protein S27 | 0.0232558 |
| POTEF | POTE ankyrin domain family, member F | 0.0232466 |
| RPS25 | ribosomal protein S25 | 0.0228568 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0222285 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0221693 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0221583 |
| RPS24 | ribosomal protein S24 | 0.0221457 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0210413 |
| HELZ | helicase with zinc finger | 0.0207887 |
| MYO1E | myosin IE | 0.0200077 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0196551 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0195416 |
| RPL31 | ribosomal protein L31 | 0.0192411 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0188301 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0181146 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | 0.0180612 |
| BBX | bobby sox homolog (Drosophila) | 0.0175641 |
| SLTM | SAFB-like, transcription modulator | 0.0172675 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0171687 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GPC6 | glypican 6 | -0.154202 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.109609 |
| ACTG1 | actin gamma 1 | -0.100124 |
| NDRG1 | N-myc downstream regulated 1 | -0.0975708 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.090495 |
| VIM | vimentin | -0.0892424 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0875161 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.087343 |
| CD2AP | CD2-associated protein | -0.0860541 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0782169 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0767202 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0756688 |
| VMP1 | vacuole membrane protein 1 | -0.0756568 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0756163 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0742323 |
| RTN4 | reticulon 4 | -0.073986 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0724272 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0691759 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.065854 |
| RPL23 | ribosomal protein L23 | -0.0655158 |
| ZNF292 | zinc finger protein 292 | -0.0579966 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0576081 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0545652 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.054212 |
| RBM25 | RNA binding motif protein 25 | -0.0517288 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0508401 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.049917 |
| EGR1 | early growth response 1 | -0.0493892 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0484309 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0455372 |
| PTK2 | protein tyrosine kinase 2 | -0.0453354 |
| CD44 | CD44 molecule (Indian blood group) | -0.0446615 |
| CALR | calreticulin | -0.0446227 |
| RBM39 | RNA binding motif protein 39 | -0.0426574 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0403814 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0373515 |
| VCL | vinculin | -0.0368429 |
| RPS8 | ribosomal protein S8 | -0.0358065 |
| EXT1 | exostosin glycosyltransferase 1 | -0.034823 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0343682 |
| ANXA2 | annexin A2 | -0.0336936 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.03298 |
| GOLGA4 | golgin A4 | -0.0315699 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | -0.0289136 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0283991 |
| PKM | pyruvate kinase, muscle | -0.027163 |
| PGK1 | phosphoglycerate kinase 1 | -0.0266901 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0257073 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0255899 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0248353 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.024773 |
| CDH13 | cadherin 13 | -0.0246225 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0245913 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0236945 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0221265 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0218478 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0213356 |
| BPTF | bromodomain PHD finger transcription factor | -0.0210634 |
| JMJD1C | jumonji domain containing 1C | -0.0201844 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.02015 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0201031 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | -0.0190235 |
| FOXJ3 | forkhead box J3 | -0.0177647 |
| SQSTM1 | sequestosome 1 | -0.0171834 |
| RPL15 | ribosomal protein L15 | -0.0167652 |
| YAP1 | Yes-associated protein 1 | -0.0152439 |
| FLNB | filamin B, beta | -0.0151597 |
| ERBIN | erbb2 interacting protein | -0.0151357 |
| GPBP1 | GC-rich promoter binding protein 1 | -0.0143741 |
| TMSB10 | thymosin beta 10 | -0.0136253 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0132121 |
| PRKCA | protein kinase C, alpha | -0.0124769 |
| MATR3 | matrin 3 | -0.0115891 |
| RPLP0 | ribosomal protein, large, P0 | -0.0112476 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | -0.0110896 |
| RPS16 | ribosomal protein S16 | -0.0102402 |
| ANKRD17 | ankyrin repeat domain 17 | -0.00981761 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.00940843 |
| RPS17 | ribosomal protein S17 | -0.00912239 |
| NF1 | neurofibromin 1 | -0.00911888 |
| ANKRD11 | ankyrin repeat domain 11 | -0.00906229 |
| EZR | ezrin | -0.00892961 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.00879401 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.00836199 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.00765036 |
| ZC3H11A | zinc finger CCCH-type containing 11A | -0.00749889 |
| HMGA2 | high mobility group AT-hook 2 | -0.00459843 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.00419013 |
| RPS3 | ribosomal protein S3 | -0.00280634 |
| RPL38 | ribosomal protein L38 | -0.0027566 |
| EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) | -0.00219773 |
| RPS21 | ribosomal protein S21 | -0.0018181 |
| RPL12 | ribosomal protein L12 | -0.00139702 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -9.54703E-4 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -9.35908E-4 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -9.29057E-4 |
| DST | dystonin | -8.57652E-4 |
