| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | venetoclax perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the venetoclax_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.32735 |
| HDAC9 | histone deacetylase 9 | 0.127425 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.112443 |
| EGFR | epidermal growth factor receptor | 0.0971568 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0904032 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.0820944 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0673151 |
| PDGFC | platelet derived growth factor C | 0.0654265 |
| TMSB4X | thymosin beta 4, X-linked | 0.0640176 |
| PRELID2 | PRELI domain containing 2 | 0.0617933 |
| AHNAK | AHNAK nucleoprotein | 0.0617748 |
| MACROD2 | MACRO domain containing 2 | 0.0608186 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0591641 |
| ZNF608 | zinc finger protein 608 | 0.0572943 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0556312 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0533789 |
| VCL | vinculin | 0.0504582 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0484167 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0483355 |
| ANXA1 | annexin A1 | 0.047856 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 | 0.0461239 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0454315 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0452447 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0421335 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0399996 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0396953 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0394529 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | 0.0387175 |
| ENO1 | enolase 1, (alpha) | 0.0382513 |
| ZNF217 | zinc finger protein 217 | 0.0377454 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0375254 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0371788 |
| TXNRD1 | thioredoxin reductase 1 | 0.036789 |
| EZR | ezrin | 0.0363157 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0356459 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0352495 |
| LDHA | lactate dehydrogenase A | 0.0341932 |
| CREB5 | cAMP responsive element binding protein 5 | 0.0341462 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0326217 |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | 0.0325294 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0323975 |
| PGK1 | phosphoglycerate kinase 1 | 0.0321182 |
| GALNT5 | polypeptide N-acetylgalactosaminyltransferase 5 | 0.031923 |
| AHCYL2 | adenosylhomocysteinase-like 2 | 0.0313484 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0311352 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | 0.0300113 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0292032 |
| SMYD3 | SET and MYND domain containing 3 | 0.0289538 |
| S100A10 | S100 calcium binding protein A10 | 0.0281094 |
| RAB27B | RAB27B, member RAS oncogene family | 0.0277393 |
| S100A6 | S100 calcium binding protein A6 | 0.0276551 |
| EFNA5 | ephrin-A5 | 0.0265752 |
| RPL4 | ribosomal protein L4 | 0.0264387 |
| PHF3 | PHD finger protein 3 | 0.0261036 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0256628 |
| BBS9 | Bardet-Biedl syndrome 9 | 0.0253701 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0253572 |
| ARB2A | ARB2 cotranscriptional regulator A | 0.0252101 |
| RPL12 | ribosomal protein L12 | 0.0250723 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0249263 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | 0.0243695 |
| TMEM65 | transmembrane protein 65 | 0.0242694 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | 0.0241975 |
| ARL4C | ADP-ribosylation factor-like 4C | 0.0240973 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.0239453 |
| JUN | jun proto-oncogene | 0.0237954 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.023728 |
| RPLP0 | ribosomal protein, large, P0 | 0.0237171 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0236314 |
| MYO5C | myosin VC | 0.0235342 |
| MPP2 | membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) | 0.023487 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0233405 |
| BPTF | bromodomain PHD finger transcription factor | 0.0230589 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.0228224 |
| RPL19 | ribosomal protein L19 | 0.0226207 |
| NT5C2 | 5'-nucleotidase, cytosolic II | 0.0223986 |
| B2M | beta-2-microglobulin | 0.0222456 |
| RPL23 | ribosomal protein L23 | 0.0217677 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | 0.0216231 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0215731 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0211232 |
| KLF6 | Kruppel-like factor 6 | 0.0210353 |
| FHAD1 | forkhead-associated (FHA) phosphopeptide binding domain 1 | 0.0209235 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0203467 |
| SEPTIN11 | septin 11 | 0.0203114 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0203104 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0199506 |
| RPL34 | ribosomal protein L34 | 0.0199073 |
| CDC73 | cell division cycle 73 | 0.0196211 |
| CLU | clusterin | 0.0195585 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.019445 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.019443 |
| SERINC1 | serine incorporator 1 | 0.0193531 |
| ATP9B | ATPase, class II, type 9B | 0.0192743 |
| RACK1 | receptor for activated C kinase 1 | 0.0191164 |
| NCKAP1 | NCK-associated protein 1 | 0.0190379 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0189121 |
| RPS6 | ribosomal protein S6 | 0.0187563 |
| MYO9A | myosin IXA | 0.0186731 |
| CREBBP | CREB binding protein | 0.0186586 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.0879759 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0695982 |
| BMP10 | bone morphogenetic protein 10 | -0.0682755 |
| PKM | pyruvate kinase, muscle | -0.0570141 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0545965 |
| NAV2 | neuron navigator 2 | -0.053919 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0501484 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0488421 |
| CACNB4 | calcium channel, voltage-dependent, beta 4 subunit | -0.0486655 |
| CENPF | centromere protein F, 350/400kDa | -0.0483808 |
| GOLGA4 | golgin A4 | -0.0483472 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0469938 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0445223 |
| MKI67 | marker of proliferation Ki-67 | -0.0421137 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0404866 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | -0.0377842 |
| SBF2 | SET binding factor 2 | -0.0375935 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0357591 |
| PFN1 | profilin 1 | -0.0357307 |
| NEBL | nebulette | -0.0355146 |
| POTEF | POTE ankyrin domain family, member F | -0.035269 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0351092 |
| LOXL3 | lysyl oxidase-like 3 | -0.0350821 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0342905 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0324642 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0324356 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0317793 |
| ATN1 | atrophin 1 | -0.030792 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.0306907 |
| UNC13A | unc-13 homolog A (C. elegans) | -0.0304444 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0293689 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0283242 |
| NPAS2 | neuronal PAS domain protein 2 | -0.028274 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0279242 |
| FLNB | filamin B, beta | -0.0278669 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0270007 |
| FOXP1 | forkhead box P1 | -0.0269788 |
| EML4 | echinoderm microtubule associated protein like 4 | -0.0269057 |
| SMC3 | structural maintenance of chromosomes 3 | -0.0267198 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.026666 |
| EVI5 | ecotropic viral integration site 5 | -0.0265618 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0264316 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0259835 |
| ANKRD11 | ankyrin repeat domain 11 | -0.025863 |
| GSE1 | Gse1 coiled-coil protein | -0.0255078 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0253116 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0252754 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0246336 |
| SETD5 | SET domain containing 5 | -0.0245216 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.0242583 |
| PCBP2 | poly(rC) binding protein 2 | -0.0241163 |
| ITGA10 | integrin, alpha 10 | -0.0239836 |
| HJURP | Holliday junction recognition protein | -0.0237976 |
| ZNF609 | zinc finger protein 609 | -0.0236367 |
| NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) | -0.0235118 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0229473 |
| RPL35A | ribosomal protein L35a | -0.0229472 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0229129 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0225514 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.021906 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0217857 |
| DENND1A | DENN/MADD domain containing 1A | -0.0216646 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | -0.0216143 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | -0.0210456 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -0.02094 |
| ACTN4 | actinin, alpha 4 | -0.0205052 |
| GPHN | gephyrin | -0.0203581 |
| RBM25 | RNA binding motif protein 25 | -0.0201667 |
| BRD4 | bromodomain containing 4 | -0.0200705 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0200687 |
| HM13 | histocompatibility (minor) 13 | -0.020055 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0197121 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0195747 |
| ARF4 | ADP-ribosylation factor 4 | -0.0195336 |
| AHI1 | Abelson helper integration site 1 | -0.0191806 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0191786 |
| TENT4A | terminal nucleotidyltransferase 4A | -0.0188887 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0186217 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.018503 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | -0.0184192 |
| TOB1 | transducer of ERBB2, 1 | -0.0182287 |
| TBC1D15 | TBC1 domain family, member 15 | -0.0181222 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0180953 |
| SYDE1 | synapse defective 1, Rho GTPase, homolog 1 (C. elegans) | -0.0179868 |
| SASH1 | SAM and SH3 domain containing 1 | -0.0176288 |
| RPL37A | ribosomal protein L37a | -0.0175594 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0174739 |
| SMNDC1 | survival motor neuron domain containing 1 | -0.0174268 |
| HMGA1 | high mobility group AT-hook 1 | -0.0171292 |
| USP3 | ubiquitin specific peptidase 3 | -0.0171136 |
| PRRC2B | proline-rich coiled-coil 2B | -0.0169415 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0168521 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0168316 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.016815 |
| BMP2K | BMP2 inducible kinase | -0.0167859 |
| FUS | FUS RNA binding protein | -0.0164089 |
| KIF18B | kinesin family member 18B | -0.0162539 |
| PIWIL1 | piwi-like RNA-mediated gene silencing 1 | -0.0162404 |
| ZRANB2 | zinc finger, RAN-binding domain containing 2 | -0.0161962 |
| AFAP1 | actin filament associated protein 1 | -0.0161886 |
