| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | venetoclax perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the venetoclax_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | 0.180703 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.140848 |
| HDAC9 | histone deacetylase 9 | 0.138425 |
| LDHA | lactate dehydrogenase A | 0.108993 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.102108 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0957461 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0906151 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | 0.0892104 |
| ENO1 | enolase 1, (alpha) | 0.0819415 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0814024 |
| DST | dystonin | 0.072745 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0725799 |
| SQSTM1 | sequestosome 1 | 0.0708755 |
| HMGA2 | high mobility group AT-hook 2 | 0.070692 |
| ASPH | aspartate beta-hydroxylase | 0.0703994 |
| VCAN | versican | 0.0668877 |
| B2M | beta-2-microglobulin | 0.0643124 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0598313 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.058251 |
| HLA-B | major histocompatibility complex, class I, B | 0.0571314 |
| GLIS3 | GLIS family zinc finger 3 | 0.0570773 |
| HLA-E | major histocompatibility complex, class I, E | 0.0558496 |
| RPS12 | ribosomal protein S12 | 0.0549444 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0546045 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0542124 |
| CANX | calnexin | 0.052688 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0526048 |
| PLIN2 | perilipin 2 | 0.0524019 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0517484 |
| RPL23 | ribosomal protein L23 | 0.0517067 |
| GOLGB1 | golgin B1 | 0.0512664 |
| RND3 | Rho family GTPase 3 | 0.0510874 |
| MT2A | metallothionein 2A | 0.0510541 |
| HLA-A | major histocompatibility complex, class I, A | 0.050545 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0484522 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0482959 |
| CDH13 | cadherin 13 | 0.0480989 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.046802 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0463858 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0440562 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.043859 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.042298 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0420314 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0415088 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0410494 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.041016 |
| FNIP1 | folliculin interacting protein 1 | 0.0405988 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0399612 |
| CD44 | CD44 molecule (Indian blood group) | 0.038814 |
| IFITM3 | interferon induced transmembrane protein 3 | 0.037657 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.037526 |
| INTS6 | integrator complex subunit 6 | 0.0371521 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.037147 |
| VCL | vinculin | 0.036813 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0358979 |
| SP100 | SP100 nuclear antigen | 0.0358182 |
| ATXN1 | ataxin 1 | 0.0352701 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0352064 |
| FTL | ferritin, light polypeptide | 0.0350961 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.034889 |
| GPC6 | glypican 6 | 0.0338712 |
| RPS8 | ribosomal protein S8 | 0.0333726 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | 0.033142 |
| CALR | calreticulin | 0.0324234 |
| RPS6 | ribosomal protein S6 | 0.0323308 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.0322991 |
| PHF3 | PHD finger protein 3 | 0.0322825 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.031457 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0310464 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0304794 |
| FRMPD4 | FERM and PDZ domain containing 4 | 0.0304511 |
| RPL37A | ribosomal protein L37a | 0.0304455 |
| VMP1 | vacuole membrane protein 1 | 0.0301921 |
| BICC1 | BicC family RNA binding protein 1 | 0.0298439 |
| EFNA5 | ephrin-A5 | 0.0296328 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.029538 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.0292368 |
| PGK1 | phosphoglycerate kinase 1 | 0.0291651 |
| KYNU | kynureninase | 0.0289525 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0286952 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0283186 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0281168 |
| STC1 | stanniocalcin 1 | 0.0280965 |
| C6ORF62 | chromosome 6 open reading frame 62 | 0.0279817 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.0279146 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0278908 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0275153 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0268582 |
| SVIL | supervillin | 0.0268339 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0268177 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0267652 |
| RIGI | RNA sensor RIG-I | 0.0267645 |
| WWOX | WW domain containing oxidoreductase | 0.0267369 |
| JMJD1C | jumonji domain containing 1C | 0.0265691 |
| RAD51B | RAD51 paralog B | 0.0264469 |
| SMYD3 | SET and MYND domain containing 3 | 0.0259279 |
| RFX3 | regulatory factor X, 3 (influences HLA class II expression) | 0.0255511 |
| BPTF | bromodomain PHD finger transcription factor | 0.0246007 |
| GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A | 0.0245196 |
| FRMD4A | FERM domain containing 4A | 0.0240894 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.159965 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.115785 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.101108 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0758177 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.060629 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0438757 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0402226 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0391793 |
| RTN4 | reticulon 4 | -0.0387044 |
| NDRG1 | N-myc downstream regulated 1 | -0.0365163 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0340576 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0327944 |
| FLNA | filamin A, alpha | -0.030987 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.030615 |
| TAPBP | TAP binding protein (tapasin) | -0.0275666 |
| ACTG1 | actin gamma 1 | -0.0268376 |
| ARF4 | ADP-ribosylation factor 4 | -0.0267285 |
| CCNL1 | cyclin L1 | -0.0261549 |
| EGR1 | early growth response 1 | -0.025229 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0242022 |
| POTEF | POTE ankyrin domain family, member F | -0.0241004 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0230103 |
| HMGA1 | high mobility group AT-hook 1 | -0.0230001 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0224404 |
| RBM39 | RNA binding motif protein 39 | -0.0218995 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0217662 |
| VEGFA | vascular endothelial growth factor A | -0.0201173 |
| ATP13A3 | ATPase type 13A3 | -0.0199737 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0199036 |
| SBF2 | SET binding factor 2 | -0.0197973 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | -0.0196688 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0195417 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.019431 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0193669 |
| GNAS | GNAS complex locus | -0.0192789 |
| TMEM41B | transmembrane protein 41B | -0.0186689 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0183932 |
| TUBB | tubulin, beta class I | -0.0182453 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0178739 |
| TMEM123 | transmembrane protein 123 | -0.0176924 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0176559 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0174956 |
| THBS1 | thrombospondin 1 | -0.0170795 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0170037 |
| USP3 | ubiquitin specific peptidase 3 | -0.0166569 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0165566 |
| WTAP | Wilms tumor 1 associated protein | -0.0165159 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0164616 |
| C3 | complement component 3 | -0.0162752 |
| ZNF292 | zinc finger protein 292 | -0.0162111 |
| OGA | O-GlcNAcase | -0.0161764 |
| MED14 | mediator complex subunit 14 | -0.0160477 |
| FOSL1 | FOS-like antigen 1 | -0.0159129 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0157472 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0156029 |
| COL1A1 | collagen, type I, alpha 1 | -0.015387 |
| FLNB | filamin B, beta | -0.0150933 |
| DENND5A | DENN/MADD domain containing 5A | -0.0149232 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | -0.0148431 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.014774 |
| SCARB1 | scavenger receptor class B, member 1 | -0.0146971 |
| RUNX2 | runt-related transcription factor 2 | -0.0146541 |
| HELZ | helicase with zinc finger | -0.0145143 |
| WASF2 | WAS protein family, member 2 | -0.0145075 |
| ANLN | anillin, actin binding protein | -0.0144954 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0141786 |
| SLC22A4 | solute carrier family 22 (organic cation/zwitterion transporter), member 4 | -0.0140714 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0140708 |
| DUSP5 | dual specificity phosphatase 5 | -0.0138093 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0137442 |
| SNX9 | sorting nexin 9 | -0.0136239 |
| FAM3C | family with sequence similarity 3, member C | -0.013259 |
| SETD5 | SET domain containing 5 | -0.0130866 |
| TENT4A | terminal nucleotidyltransferase 4A | -0.0128351 |
| TFG | TRK-fused gene | -0.0127501 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | -0.0127047 |
| FUS | FUS RNA binding protein | -0.0124999 |
| TXNRD1 | thioredoxin reductase 1 | -0.0123912 |
| CDC27 | cell division cycle 27 | -0.0123009 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0122369 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0122073 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -0.0121418 |
| TBC1D12 | TBC1 domain family, member 12 | -0.0121001 |
| ADAM17 | ADAM metallopeptidase domain 17 | -0.0118731 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0116042 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0115769 |
| WDR45B | WD repeat domain 45B | -0.0115762 |
| RPRD1B | regulation of nuclear pre-mRNA domain containing 1B | -0.0115033 |
| RNF145 | ring finger protein 145 | -0.0114384 |
| ZFAND6 | zinc finger, AN1-type domain 6 | -0.0114381 |
| MED23 | mediator complex subunit 23 | -0.0114225 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0111437 |
| RASA2 | RAS p21 protein activator 2 | -0.0111266 |
| AGRN | agrin | -0.0111241 |
| HBP1 | HMG-box transcription factor 1 | -0.0111164 |
| MAP4 | microtubule-associated protein 4 | -0.0111158 |
| SAR1A | secretion associated, Ras related GTPase 1A | -0.0110854 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | -0.0109417 |
| GORASP2 | golgi reassembly stacking protein 2, 55kDa | -0.0109237 |
| MEF2D | myocyte enhancer factor 2D | -0.0108585 |
