| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | venetoclax perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the venetoclax_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.132431 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.130361 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.120135 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.105832 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0921184 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0910999 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.086079 |
| ANXA2 | annexin A2 | 0.0751284 |
| LDHA | lactate dehydrogenase A | 0.069976 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0697389 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0683699 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.065326 |
| INTS6 | integrator complex subunit 6 | 0.0633782 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0626059 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0604899 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0603274 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0600765 |
| SVIL | supervillin | 0.0598291 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0590161 |
| SQSTM1 | sequestosome 1 | 0.0552607 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0524078 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0511309 |
| ANXA1 | annexin A1 | 0.0509599 |
| SMAD3 | SMAD family member 3 | 0.0494494 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0484998 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0468669 |
| RORA | RAR-related orphan receptor A | 0.0467561 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0467172 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0466822 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0465351 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0465045 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0458409 |
| DST | dystonin | 0.0457025 |
| RIGI | RNA sensor RIG-I | 0.0440615 |
| ENO1 | enolase 1, (alpha) | 0.0438899 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0435344 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.0426907 |
| MYOF | myoferlin | 0.0420777 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0413735 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0397225 |
| B2M | beta-2-microglobulin | 0.0392079 |
| PRKCA | protein kinase C, alpha | 0.038908 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0387049 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.0386343 |
| TXNIP | thioredoxin interacting protein | 0.038578 |
| OASL | 2'-5'-oligoadenylate synthetase-like | 0.0383654 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0379095 |
| OXSR1 | oxidative stress responsive 1 | 0.037884 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0373615 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0365509 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0362785 |
| ELOF1 | elongation factor 1 homolog (S. cerevisiae) | 0.0362038 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.0350373 |
| EGFR | epidermal growth factor receptor | 0.0347957 |
| SPAG9 | sperm associated antigen 9 | 0.0343547 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0338974 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | 0.0338572 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0335446 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0334514 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0334423 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | 0.0332701 |
| SIK3 | SIK family kinase 3 | 0.0331687 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0319545 |
| DYNC2H1 | dynein, cytoplasmic 2, heavy chain 1 | 0.031807 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0317711 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.031592 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0314554 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.0314187 |
| HDAC9 | histone deacetylase 9 | 0.0313789 |
| SET | SET nuclear proto-oncogene | 0.0313335 |
| KIF5B | kinesin family member 5B | 0.0312176 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0312016 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.03099 |
| NSD1 | nuclear receptor binding SET domain protein 1 | 0.0303455 |
| ANO6 | anoctamin 6 | 0.0296357 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0295611 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0295474 |
| BPTF | bromodomain PHD finger transcription factor | 0.028901 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0288883 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.0287145 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | 0.0284761 |
| ASPH | aspartate beta-hydroxylase | 0.0283793 |
| CANX | calnexin | 0.0282792 |
| TXNRD1 | thioredoxin reductase 1 | 0.027927 |
| PRSS23 | protease, serine, 23 | 0.0278848 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0277225 |
| FMNL2 | formin-like 2 | 0.0275977 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.027297 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.0270129 |
| TPI1 | triosephosphate isomerase 1 | 0.0268527 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0267663 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.026709 |
| JMJD1C | jumonji domain containing 1C | 0.0265154 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0265067 |
| WWOX | WW domain containing oxidoreductase | 0.0262725 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | 0.0261148 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0260717 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0256605 |
| UBC | ubiquitin C | 0.0255783 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0255535 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PKM | pyruvate kinase, muscle | -0.0574547 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0505066 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0457149 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0408776 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | -0.039316 |
| IGF2 | insulin-like growth factor 2 | -0.0392394 |
| UBE2K | ubiquitin-conjugating enzyme E2K | -0.0371608 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0369725 |
| DNER | delta/notch-like EGF repeat containing | -0.0359802 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0359329 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0358936 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0357572 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | -0.0351849 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0344984 |
| RBM39 | RNA binding motif protein 39 | -0.0344207 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0343056 |
| NKTR | natural killer cell triggering receptor | -0.0337808 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0319478 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.031496 |
| HMGA1 | high mobility group AT-hook 1 | -0.0309949 |
| DIAPH3 | diaphanous-related formin 3 | -0.0304555 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0303524 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | -0.0292258 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0291393 |
| ZNF292 | zinc finger protein 292 | -0.0288857 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | -0.0288847 |
| PYGL | phosphorylase, glycogen, liver | -0.0283353 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0279194 |
| AHNAK | AHNAK nucleoprotein | -0.0278518 |
| FAM3C | family with sequence similarity 3, member C | -0.0276794 |
| NALCN | sodium leak channel, non selective | -0.0273677 |
| BRD4 | bromodomain containing 4 | -0.0272054 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0268369 |
| TPM4 | tropomyosin 4 | -0.0266963 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0265416 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0262374 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | -0.0260095 |
| DERA | deoxyribose-phosphate aldolase (putative) | -0.0259713 |
| NLRP1 | NLR family, pyrin domain containing 1 | -0.0255233 |
| LRCH3 | leucine-rich repeats and calponin homology (CH) domain containing 3 | -0.0254785 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.025326 |
| RIN2 | Ras and Rab interactor 2 | -0.0252143 |
| CDK5RAP1 | CDK5 regulatory subunit associated protein 1 | -0.0250687 |
| TPR | translocated promoter region, nuclear basket protein | -0.0250271 |
| RABGAP1 | RAB GTPase activating protein 1 | -0.0249061 |
| RTN4 | reticulon 4 | -0.0246717 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | -0.0246566 |
| PSMD5 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 5 | -0.0245856 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0244042 |
| CDC42SE2 | CDC42 small effector 2 | -0.0243281 |
| RAB6A | RAB6A, member RAS oncogene family | -0.024314 |
| PRKCE | protein kinase C, epsilon | -0.0243102 |
| NUP214 | nucleoporin 214kDa | -0.0241349 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0241213 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.0239669 |
| VIM | vimentin | -0.0239122 |
| LAMA5 | laminin, alpha 5 | -0.0238515 |
| SPRY4 | sprouty homolog 4 (Drosophila) | -0.0238499 |
| CUL5 | cullin 5 | -0.0238489 |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase | -0.0238486 |
| PRRC2B | proline-rich coiled-coil 2B | -0.0238025 |
| SAFB2 | scaffold attachment factor B2 | -0.0236174 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0235928 |
| AKAP10 | A kinase (PRKA) anchor protein 10 | -0.0234274 |
| USP3 | ubiquitin specific peptidase 3 | -0.0232447 |
| MED17 | mediator complex subunit 17 | -0.0231365 |
| MSN | moesin | -0.022339 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0223246 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0223074 |
| HM13 | histocompatibility (minor) 13 | -0.022286 |
| PIK3CB | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta | -0.0219079 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0217373 |
| AUH | AU RNA binding protein/enoyl-CoA hydratase | -0.0216828 |
| COG5 | component of oligomeric golgi complex 5 | -0.0215585 |
| PCBP2 | poly(rC) binding protein 2 | -0.0214876 |
| ARF4 | ADP-ribosylation factor 4 | -0.0214199 |
| ST3GAL3 | ST3 beta-galactoside alpha-2,3-sialyltransferase 3 | -0.0211427 |
| PTBP2 | polypyrimidine tract binding protein 2 | -0.0210692 |
| TPST1 | tyrosylprotein sulfotransferase 1 | -0.020608 |
| AFF4 | AF4/FMR2 family, member 4 | -0.020581 |
| BRD8 | bromodomain containing 8 | -0.0205664 |
| RREB1 | ras responsive element binding protein 1 | -0.0204421 |
| WASHC4 | WASH complex subunit 4 | -0.0201869 |
| AVL9 | AVL9 homolog (S. cerevisiase) | -0.0199821 |
| ATF7IP | activating transcription factor 7 interacting protein | -0.0199793 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | -0.019796 |
| HIPK3 | homeodomain interacting protein kinase 3 | -0.0197817 |
| PFN1 | profilin 1 | -0.019671 |
| SMAP1 | small ArfGAP 1 | -0.0196102 |
| BSG | basigin (Ok blood group) | -0.0195415 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | -0.0193895 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0193554 |
| APOLD1 | apolipoprotein L domain containing 1 | -0.0192538 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0191334 |
| FAM222B | family with sequence similarity 222, member B | -0.0189975 |
| ZBTB35 | zinc finger and BTB domain containing 35 | -0.0189506 |
| GAS2L3 | growth arrest-specific 2 like 3 | -0.0187369 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0184677 |
| NAA35 | N(alpha)-acetyltransferase 35, NatC auxiliary subunit | -0.0184579 |
| ITGB4 | integrin, beta 4 | -0.0184427 |
