| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | venetoclax perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the venetoclax_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EXT1 | exostosin glycosyltransferase 1 | 0.101333 |
| ASPH | aspartate beta-hydroxylase | 0.0780627 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0688373 |
| CENPF | centromere protein F, 350/400kDa | 0.0633483 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0623415 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0621755 |
| B2M | beta-2-microglobulin | 0.0616979 |
| ENO1 | enolase 1, (alpha) | 0.0616598 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0609725 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.059018 |
| VIM | vimentin | 0.0570276 |
| DST | dystonin | 0.0560569 |
| MT2A | metallothionein 2A | 0.0551619 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0536919 |
| SVIL | supervillin | 0.0521288 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0518019 |
| OSMR | oncostatin M receptor | 0.0506501 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | 0.0503211 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0483092 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0481354 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0469552 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0454273 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.044342 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0436939 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0432626 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.0412768 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0399269 |
| TXNRD1 | thioredoxin reductase 1 | 0.0397799 |
| TPR | translocated promoter region, nuclear basket protein | 0.0396631 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0393795 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0380709 |
| IFI44L | interferon-induced protein 44-like | 0.0380532 |
| AHR | aryl hydrocarbon receptor | 0.0360031 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.035399 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.035367 |
| PLIN2 | perilipin 2 | 0.0341637 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0339557 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0335704 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0335679 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0333121 |
| RNF213 | ring finger protein 213 | 0.0329567 |
| TXNIP | thioredoxin interacting protein | 0.0326132 |
| MKI67 | marker of proliferation Ki-67 | 0.0322123 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0315096 |
| MYOF | myoferlin | 0.0314394 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0308218 |
| SFTPA2 | surfactant protein A2 | 0.0307921 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0307158 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0295847 |
| FHIT | fragile histidine triad | 0.0295008 |
| PRELID2 | PRELI domain containing 2 | 0.0277416 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0275003 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0274451 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0266151 |
| RAB10 | RAB10, member RAS oncogene family | 0.0265768 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0265517 |
| CANX | calnexin | 0.0265399 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.026474 |
| YBX3 | Y box binding protein 3 | 0.0263734 |
| IL6ST | interleukin 6 signal transducer | 0.026133 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0260165 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0258752 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0258746 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.02579 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0251655 |
| SERINC1 | serine incorporator 1 | 0.0251259 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0249495 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0246804 |
| NTN4 | netrin 4 | 0.0245035 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0244554 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.024394 |
| SQSTM1 | sequestosome 1 | 0.0243242 |
| SP100 | SP100 nuclear antigen | 0.0242029 |
| DSTN | destrin (actin depolymerizing factor) | 0.0239698 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0239267 |
| RAD51B | RAD51 paralog B | 0.0235283 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0233401 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0231181 |
| MX2 | MX dynamin-like GTPase 2 | 0.0230997 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | 0.0229532 |
| IFITM1 | interferon induced transmembrane protein 1 | 0.0229115 |
| CAB39 | calcium binding protein 39 | 0.0228925 |
| FAM13A | family with sequence similarity 13, member A | 0.0228695 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.02281 |
| BOD1L1 | biorientation of chromosomes in cell division 1-like 1 | 0.0227935 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.022793 |
| MX1 | MX dynamin-like GTPase 1 | 0.0226466 |
| IL6 | interleukin 6 | 0.0226242 |
| S100A10 | S100 calcium binding protein A10 | 0.0223142 |
| SMYD3 | SET and MYND domain containing 3 | 0.0219922 |
| NCOA7 | nuclear receptor coactivator 7 | 0.0215728 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.0213643 |
| AGPAT4 | 1-acylglycerol-3-phosphate O-acyltransferase 4 | 0.0212057 |
| SIRT1 | sirtuin 1 | 0.0211481 |
| MYO1E | myosin IE | 0.0210106 |
| RFX2 | regulatory factor X, 2 (influences HLA class II expression) | 0.0210079 |
| FTL | ferritin, light polypeptide | 0.0209439 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0209033 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0208801 |
| BPTF | bromodomain PHD finger transcription factor | 0.0206359 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NRG1 | neuregulin 1 | -0.203521 |
| FN1 | fibronectin 1 | -0.174202 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.142638 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.1199 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.119235 |
| NDRG1 | N-myc downstream regulated 1 | -0.0996167 |
| HMGA2 | high mobility group AT-hook 2 | -0.0992723 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0708804 |
| GRB10 | growth factor receptor-bound protein 10 | -0.062765 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0591255 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0482312 |
| EGR1 | early growth response 1 | -0.0445547 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0419582 |
| VEGFA | vascular endothelial growth factor A | -0.0386382 |
| HMGA1 | high mobility group AT-hook 1 | -0.0377413 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0347047 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0344462 |
| RAI14 | retinoic acid induced 14 | -0.0332868 |
| PTMA | prothymosin, alpha | -0.030189 |
| ACTG1 | actin gamma 1 | -0.02802 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0261209 |
| TMSB10 | thymosin beta 10 | -0.0259947 |
| FLNA | filamin A, alpha | -0.0259741 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.025369 |
| HPCAL1 | hippocalcin-like 1 | -0.0251099 |
| HIPK2 | homeodomain interacting protein kinase 2 | -0.0249889 |
| COPA | coatomer protein complex, subunit alpha | -0.0249659 |
| PKM | pyruvate kinase, muscle | -0.0249267 |
| ATN1 | atrophin 1 | -0.0244514 |
| FOSL1 | FOS-like antigen 1 | -0.0238895 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0237184 |
| FAM20C | family with sequence similarity 20, member C | -0.02345 |
| ITGA1 | integrin, alpha 1 | -0.0233322 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0232246 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0225952 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0219417 |
| SUCO | SUN domain containing ossification factor | -0.0212761 |
| CADM1 | cell adhesion molecule 1 | -0.0208025 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0206546 |
| LOX | lysyl oxidase | -0.0203892 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0203681 |
| RPL28 | ribosomal protein L28 | -0.0197365 |
| ARF4 | ADP-ribosylation factor 4 | -0.0195118 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0190687 |
| PIM3 | Pim-3 proto-oncogene, serine/threonine kinase | -0.0190149 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.018747 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0185968 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0185686 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.018386 |
| MCL1 | myeloid cell leukemia 1 | -0.0181007 |
| BRD2 | bromodomain containing 2 | -0.0178335 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0177048 |
| ADAM8 | ADAM metallopeptidase domain 8 | -0.0176505 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0175653 |
| MORF4L2 | mortality factor 4 like 2 | -0.0171698 |
| RPS5 | ribosomal protein S5 | -0.0169308 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0168802 |
| RPS3 | ribosomal protein S3 | -0.0168632 |
| NUP58 | nucleoporin 58 | -0.0167316 |
| ERO1B | endoplasmic reticulum oxidoreductase 1 beta | -0.0166389 |
| CCNL1 | cyclin L1 | -0.0164834 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0164457 |
| GNAS | GNAS complex locus | -0.0164254 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0164066 |
| TENM4 | teneurin transmembrane protein 4 | -0.0163808 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | -0.0163144 |
| SLC35F3 | solute carrier family 35, member F3 | -0.01629 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | -0.0162352 |
| MAP4K3 | mitogen-activated protein kinase kinase kinase kinase 3 | -0.0161343 |
| TMEM165 | transmembrane protein 165 | -0.0161221 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -0.0159324 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0158722 |
| NOP58 | NOP58 ribonucleoprotein | -0.0158505 |
| PPP1R15B | protein phosphatase 1, regulatory subunit 15B | -0.015706 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.015369 |
| MIDEAS | mitotic deacetylase associated SANT domain protein | -0.0152617 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0152375 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.015225 |
| GLIS3 | GLIS family zinc finger 3 | -0.0151935 |
| RPL35A | ribosomal protein L35a | -0.0151733 |
| FBXO11 | F-box protein 11 | -0.0151663 |
| USP3 | ubiquitin specific peptidase 3 | -0.0149693 |
| SEC24D | SEC24 family member D | -0.0149416 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0146932 |
| QSOX1 | quiescin Q6 sulfhydryl oxidase 1 | -0.0144706 |
| PLEC | plectin | -0.0144584 |
| POTEF | POTE ankyrin domain family, member F | -0.0144427 |
| NAV1 | neuron navigator 1 | -0.0144389 |
| SLAIN2 | SLAIN motif family, member 2 | -0.0143109 |
| COG6 | component of oligomeric golgi complex 6 | -0.0142956 |
| PRKCA | protein kinase C, alpha | -0.0142465 |
| SHB | Src homology 2 domain containing adaptor protein B | -0.014113 |
| PTGES2 | prostaglandin E synthase 2 | -0.0141082 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0140791 |
| LMAN2 | lectin, mannose-binding 2 | -0.0139997 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0139382 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | -0.0139341 |
| ALKBH5 | AlkB family member 5, RNA demethylase | -0.013865 |
| AGO2 | argonaute RISC catalytic component 2 | -0.0138119 |
| EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) | -0.0138047 |
