verapamil-161 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the verapamil-161 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAK1 AP2 associated kinase 1
ADAM12 ADAM metallopeptidase domain 12
ALPPL2 alkaline phosphatase, placental-like 2
AP4M1 adaptor-related protein complex 4, mu 1 subunit
APBA1 amyloid beta (A4) precursor protein-binding, family A, member 1
ATXN2L ataxin 2-like
AXIN1 axin 1
C14ORF79 chromosome 14 open reading frame 79
C1ORF61 chromosome 1 open reading frame 61
CD248 CD248 molecule, endosialin
CIR1 corepressor interacting with RBPJ, 1
CLIC4 chloride intracellular channel 4
CNTFR ciliary neurotrophic factor receptor
COX5B cytochrome c oxidase subunit Vb
CRCP CGRP receptor component
CTTN cortactin
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
DGCR2 DiGeorge syndrome critical region gene 2
DHX34 DEAH (Asp-Glu-Ala-His) box polypeptide 34
DLG3 discs, large homolog 3 (Drosophila)
DLK2 delta-like 2 homolog (Drosophila)
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12
DPY19L1 dpy-19-like 1 (C. elegans)
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
EIF5A eukaryotic translation initiation factor 5A
ERN2 endoplasmic reticulum to nucleus signaling 2
ETV1 ets variant 1
FAM153A family with sequence similarity 153, member A
FCN2 ficolin (collagen/fibrinogen domain containing lectin) 2
FRAS1 Fraser extracellular matrix complex subunit 1
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2
GOLGA2 golgin A2
GPR27 G protein-coupled receptor 27
HABP4 hyaluronan binding protein 4
HLA-G major histocompatibility complex, class I, G
HNRNPA3 heterogeneous nuclear ribonucleoprotein A3
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
IKZF1 IKAROS family zinc finger 1 (Ikaros)
KCNAB2 potassium channel, voltage gated subfamily A regulatory beta subunit 2
KIR2DS1 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1
L3MBTL1 l(3)mbt-like 1 (Drosophila)
LECT1 leukocyte cell derived chemotaxin 1
LMNA lamin A/C
MAGED2 melanoma antigen family D2
MEFV Mediterranean fever
METTL22 methyltransferase like 22
MIIP migration and invasion inhibitory protein
MOB3B MOB kinase activator 3B
MPPED1 metallophosphoesterase domain containing 1
MYL10 myosin, light chain 10, regulatory
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NOP14-AS1 NOP14 antisense RNA 1
NPPA natriuretic peptide A
NUDT2 nudix (nucleoside diphosphate linked moiety X)-type motif 2
PDCD1 programmed cell death 1
PHLDB1 pleckstrin homology-like domain, family B, member 1
PLIN2 perilipin 2
POGZ pogo transposable element with ZNF domain
POU2F2 POU class 2 homeobox 2
PRAMEF11 PRAME family member 11
PRRG2 proline rich Gla (G-carboxyglutamic acid) 2
PRX periaxin
PTN pleiotrophin
RAB29 RAB29, member RAS oncogene family
RAB2A RAB2A, member RAS oncogene family
RMND5B required for meiotic nuclear division 5 homolog B (S. cerevisiae)
RPL14 ribosomal protein L14
RPL27A ribosomal protein L27a
RPLP2 ribosomal protein, large, P2
RPS11 ribosomal protein S11
RRP1B ribosomal RNA processing 1B
SCAPER S-phase cyclin A-associated protein in the ER
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
SIGLEC6 sialic acid binding Ig-like lectin 6
SOX4 SRY (sex determining region Y)-box 4
SPDEF SAM pointed domain containing ETS transcription factor
SPINK4 serine peptidase inhibitor, Kazal type 4
SPRR1A small proline-rich protein 1A
ST20 suppressor of tumorigenicity 20
ST7 suppression of tumorigenicity 7
TAC3 tachykinin 3
TAF6L TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
TCF3 transcription factor 3
TCP10L t-complex 10-like
TMEM63A transmembrane protein 63A
TRAF3 TNF receptor-associated factor 3
TSPAN9 tetraspanin 9
UBQLN4 ubiquilin 4
VIPR2 vasoactive intestinal peptide receptor 2
WAS Wiskott-Aldrich syndrome
ZBTB40 zinc finger and BTB domain containing 40
ZC3H7B zinc finger CCCH-type containing 7B
ZIM2 zinc finger, imprinted 2
ZNF747 zinc finger protein 747

decreased expression

Symbol Name
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ACBD3 acyl-CoA binding domain containing 3
ADCK3 aarF domain containing kinase 3
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1
AGO2 argonaute RISC catalytic component 2
AMMECR1 Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1
AMOTL2 angiomotin like 2
APIP APAF1 interacting protein
ARHGAP12 Rho GTPase activating protein 12
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5
C11ORF68 chromosome 11 open reading frame 68
CA2 carbonic anhydrase II
CCDC109B coiled-coil domain containing 109B
CCDC59 coiled-coil domain containing 59
CD320 CD320 molecule
CDC23 cell division cycle 23
CDC73 cell division cycle 73
CDK5RAP3 CDK5 regulatory subunit associated protein 3
CDT1 chromatin licensing and DNA replication factor 1
CEP85 centrosomal protein 85kDa
CISH cytokine inducible SH2-containing protein
COPS5 COP9 signalosome subunit 5
CPSF7 cleavage and polyadenylation specific factor 7, 59kDa
CRBN cereblon
CRNKL1 crooked neck pre-mRNA splicing factor 1
CTAGE9 CTAGE family, member 9
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
DCPS decapping enzyme, scavenger
DDA1 DET1 and DDB1 associated 1
DEK DEK proto-oncogene
DENR density-regulated protein
DHX38 DEAH (Asp-Glu-Ala-His) box polypeptide 38
EDC3 enhancer of mRNA decapping 3
FAH fumarylacetoacetate hydrolase (fumarylacetoacetase)
FASTKD1 FAST kinase domains 1
FCHO1 FCH domain only 1
FKBPL FK506 binding protein like
GATAD2A GATA zinc finger domain containing 2A
GBAP1 glucosidase, beta, acid pseudogene 1
GOLPH3 golgi phosphoprotein 3 (coat-protein)
GOLT1B golgi transport 1B
GRAMD4 GRAM domain containing 4
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa
HIST1H3G histone cluster 1, H3g
HIST1H4J histone cluster 1, H4j
IRX5 iroquois homeobox 5
JOSD1 Josephin domain containing 1
KIF4A kinesin family member 4A
LANCL2 LanC lantibiotic synthetase component C-like 2 (bacterial)
LBR lamin B receptor
LRFN4 leucine rich repeat and fibronectin type III domain containing 4
LRIF1 ligand dependent nuclear receptor interacting factor 1
LTBP3 latent transforming growth factor beta binding protein 3
MANBA mannosidase, beta A, lysosomal
MTERF3 mitochondrial transcription termination factor 3
MYO9A myosin IXA
NARFL nuclear prelamin A recognition factor-like
NIP7 NIP7, nucleolar pre-rRNA processing protein
NRSN2 neurensin 2
OXCT1 3-oxoacid CoA transferase 1
PCSK7 proprotein convertase subtilisin/kexin type 7
PEX13 peroxisomal biogenesis factor 13
PGS1 phosphatidylglycerophosphate synthase 1
PHLDA2 pleckstrin homology-like domain, family A, member 2
PLEKHO2 pleckstrin homology domain containing, family O member 2
PPP1R8 protein phosphatase 1, regulatory subunit 8
PRR15L proline rich 15-like
RAB32 RAB32, member RAS oncogene family
RAP1A RAP1A, member of RAS oncogene family
RBM14 RNA binding motif protein 14
REEP4 receptor accessory protein 4
RIOK2 RIO kinase 2
RNF220 ring finger protein 220
RPAP1 RNA polymerase II associated protein 1
RPAP3 RNA polymerase II associated protein 3
RRP1 ribosomal RNA processing 1
SEH1L SEH1-like (S. cerevisiae)
SELENBP1 selenium binding protein 1
SF3A2 splicing factor 3a, subunit 2, 66kDa
SLC22A18 solute carrier family 22, member 18
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SLMO2 slowmo homolog 2 (Drosophila)
SMYD5 SMYD family member 5
SNX17 sorting nexin 17
SPG7 spastic paraplegia 7 (pure and complicated autosomal recessive)
ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1
TGFBRAP1 transforming growth factor, beta receptor associated protein 1
TINF2 TERF1 (TRF1)-interacting nuclear factor 2
TM7SF2 transmembrane 7 superfamily member 2
TMEM160 transmembrane protein 160
TOE1 target of EGR1, member 1 (nuclear)
TPCN1 two pore segment channel 1
UBP1 upstream binding protein 1 (LBP-1a)
UBQLN2 ubiquilin 2
UFM1 ubiquitin-fold modifier 1
WDR13 WD repeat domain 13
WDR46 WD repeat domain 46
YBX2 Y box binding protein 2
ZBTB24 zinc finger and BTB domain containing 24