verapamil-2009 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the verapamil-2009 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACAN aggrecan
AKTIP AKT interacting protein
ALDH3B1 aldehyde dehydrogenase 3 family, member B1
ALPK1 alpha-kinase 1
AP1G2 adaptor-related protein complex 1, gamma 2 subunit
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C
APP amyloid beta (A4) precursor protein
ARFGAP3 ADP-ribosylation factor GTPase activating protein 3
ARRB1 arrestin, beta 1
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
ASB8 ankyrin repeat and SOCS box containing 8
ATPAF2 ATP synthase mitochondrial F1 complex assembly factor 2
C16ORF58 chromosome 16 open reading frame 58
C1ORF61 chromosome 1 open reading frame 61
C7ORF43 chromosome 7 open reading frame 43
CACFD1 calcium channel flower domain containing 1
CADM1 cell adhesion molecule 1
CCDC71 coiled-coil domain containing 71
CD46 CD46 molecule, complement regulatory protein
CHMP6 charged multivesicular body protein 6
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CREBZF CREB/ATF bZIP transcription factor
CRMP1 collapsin response mediator protein 1
CRTC1 CREB regulated transcription coactivator 1
CXCL8 chemokine (C-X-C motif) ligand 8
CYSLTR2 cysteinyl leukotriene receptor 2
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
DNAJC16 DnaJ (Hsp40) homolog, subfamily C, member 16
EID1 EP300 interacting inhibitor of differentiation 1
FAM188A family with sequence similarity 188, member A
FAM3A family with sequence similarity 3, member A
FASTK Fas-activated serine/threonine kinase
G0S2 G0/G1 switch 2
GAS8 growth arrest-specific 8
GMDS GDP-mannose 4,6-dehydratase
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GOSR2 golgi SNAP receptor complex member 2
GTF2F2 general transcription factor IIF, polypeptide 2, 30kDa
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HNMT histamine N-methyltransferase
HOXC4 homeobox C4
HTRA2 HtrA serine peptidase 2
IDH3G isocitrate dehydrogenase 3 (NAD+) gamma
KCNA3 potassium channel, voltage gated shaker related subfamily A, member 3
KIFC3 kinesin family member C3
KLF2 Kruppel-like factor 2
KLF5 Kruppel-like factor 5 (intestinal)
KLHL18 kelch-like family member 18
KLK1 kallikrein 1
KRT6B keratin 6B, type II
LILRA2 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2
LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
LILRB2 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MOB3B MOB kinase activator 3B
MTM1 myotubularin 1
N4BP1 NEDD4 binding protein 1
NMT1 N-myristoyltransferase 1
NPM3 nucleophosmin/nucleoplasmin 3
NUDT2 nudix (nucleoside diphosphate linked moiety X)-type motif 2
NUP160 nucleoporin 160kDa
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4
PDGFB platelet-derived growth factor beta polypeptide
PIAS4 protein inhibitor of activated STAT, 4
PKP3 plakophilin 3
PLSCR1 phospholipid scramblase 1
POLR3G polymerase (RNA) III (DNA directed) polypeptide G (32kD)
RAB11FIP5 RAB11 family interacting protein 5 (class I)
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
RHO rhodopsin
RNF216 ring finger protein 216
RRP1B ribosomal RNA processing 1B
SAT1 spermidine/spermine N1-acetyltransferase 1
SCAMP1 secretory carrier membrane protein 1
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SH2D3A SH2 domain containing 3A
SLC22A18 solute carrier family 22, member 18
SPTB spectrin, beta, erythrocytic
ST6GALNAC4 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4
STAT5A signal transducer and activator of transcription 5A
STK16 serine/threonine kinase 16
TBC1D4 TBC1 domain family, member 4
TBX6 T-box 6
TCP11L1 t-complex 11, testis-specific-like 1
THY1 Thy-1 cell surface antigen
TLE4 transducin-like enhancer of split 4
TMED1 transmembrane emp24 protein transport domain containing 1
TMEM70 transmembrane protein 70
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TPD52L1 tumor protein D52-like 1
TRABD TraB domain containing
TSC22D3 TSC22 domain family, member 3
TUBGCP2 tubulin, gamma complex associated protein 2
VGF VGF nerve growth factor inducible
WSB1 WD repeat and SOCS box containing 1
ZMYM6 zinc finger, MYM-type 6
ZNF747 zinc finger protein 747
ZNF79 zinc finger protein 79
ZSCAN26 zinc finger and SCAN domain containing 26

decreased expression

Symbol Name
AGO2 argonaute RISC catalytic component 2
ANKRD46 ankyrin repeat domain 46
ANKZF1 ankyrin repeat and zinc finger domain containing 1
ARID4A AT rich interactive domain 4A (RBP1-like)
ASAP1-IT1 ASAP1 intronic transcript 1
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
ATG9A autophagy related 9A
AXIN1 axin 1
BAHD1 bromo adjacent homology domain containing 1
CCNB1 cyclin B1
CDC20 cell division cycle 20
CDK5RAP2 CDK5 regulatory subunit associated protein 2
CDKN3 cyclin-dependent kinase inhibitor 3
CENPE centromere protein E, 312kDa
CMTR1 cap methyltransferase 1
CPNE1 copine I
CS citrate synthase
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
DEPDC1 DEP domain containing 1
DHRS7B dehydrogenase/reductase (SDR family) member 7B
DLGAP5 discs, large (Drosophila) homolog-associated protein 5
DPYD dihydropyrimidine dehydrogenase
EDAR ectodysplasin A receptor
FAM114A2 family with sequence similarity 114, member A2
FAM53C family with sequence similarity 53, member C
FANCF Fanconi anemia, complementation group F
FMNL1 formin-like 1
FOXK2 forkhead box K2
FOXM1 forkhead box M1
FPGS folylpolyglutamate synthase
FUBP3 far upstream element (FUSE) binding protein 3
GAB2 GRB2-associated binding protein 2
GINS4 GINS complex subunit 4 (Sld5 homolog)
GUSBP3 glucuronidase, beta pseudogene 3
H1FX H1 histone family, member X
HIRA histone cell cycle regulator
HIST1H1C histone cluster 1, H1c
HIST1H1E histone cluster 1, H1e
HIST1H2BF histone cluster 1, H2bf
HIST1H4C histone cluster 1, H4c
HMMR hyaluronan-mediated motility receptor (RHAMM)
IP6K1 inositol hexakisphosphate kinase 1
KIAA0922 KIAA0922
KIF11 kinesin family member 11
KIF14 kinesin family member 14
KIF18A kinesin family member 18A
KIF20A kinesin family member 20A
KIFC1 kinesin family member C1
KIZ kizuna centrosomal protein
KLHDC10 kelch domain containing 10
LOC642236 FSHD region gene 1 pseudogene
LRPAP1 low density lipoprotein receptor-related protein associated protein 1
MED22 mediator complex subunit 22
METTL21B methyltransferase like 21B
METTL4 methyltransferase like 4
MLPH melanophilin
MYL12B myosin, light chain 12B, regulatory
MYLIP myosin regulatory light chain interacting protein
NABP2 nucleic acid binding protein 2
NDC80 NDC80 kinetochore complex component
NDUFA1 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa
NME6 NME/NM23 nucleoside diphosphate kinase 6
NUBP2 nucleotide binding protein 2
PEMT phosphatidylethanolamine N-methyltransferase
PHACTR4 phosphatase and actin regulator 4
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1
PKN1 protein kinase N1
PLK1 polo-like kinase 1
PNRC1 proline-rich nuclear receptor coactivator 1
PPP1R10 protein phosphatase 1, regulatory subunit 10
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PRC1 protein regulator of cytokinesis 1
PRKRIP1 PRKR interacting protein 1 (IL11 inducible)
PSRC1 proline/serine-rich coiled-coil 1
RGP1 RGP1 retrograde golgi transport homolog (S. cerevisiae)
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
RNF103 ring finger protein 103
RRN3 RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae)
SEC61B Sec61 beta subunit
SLC10A1 solute carrier family 10 (sodium/bile acid cotransporter), member 1
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5
SLC35C2 solute carrier family 35 (GDP-fucose transporter), member C2
SNX6 sorting nexin 6
TCTN2 tectonic family member 2
TEX40 testis expressed 40
TGS1 trimethylguanosine synthase 1
TMEM184B transmembrane protein 184B
TOP2A topoisomerase (DNA) II alpha 170kDa
TOR4A torsin family 4, member A
TSR2 TSR2, 20S rRNA accumulation, homolog (S. cerevisiae)
UBE2C ubiquitin-conjugating enzyme E2C
UBQLN4 ubiquilin 4
UNKL unkempt family zinc finger-like
WDR26 WD repeat domain 26
ZC3H4 zinc finger CCCH-type containing 4
ZCCHC2 zinc finger, CCHC domain containing 2
ZKSCAN4 zinc finger with KRAB and SCAN domains 4
ZNF32 zinc finger protein 32
ZNF652 zinc finger protein 652