verapamil-6287 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
Similar Terms
Downloads & Tools

Genes

197 genes differentially expressed following the verapamil-6287 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ACVR1B activin A receptor, type IB
ADRA1A adrenoceptor alpha 1A
AHNAK AHNAK nucleoprotein
ALDH3B1 aldehyde dehydrogenase 3 family, member B1
AMDHD2 amidohydrolase domain containing 2
ANXA10 annexin A10
APOBEC3A apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A
ARHGEF11 Rho guanine nucleotide exchange factor (GEF) 11
ARTN artemin
BAHCC1 BAH domain and coiled-coil containing 1
BHLHE40 basic helix-loop-helix family, member e40
CALD1 caldesmon 1
CCR4 chemokine (C-C motif) receptor 4
CGA glycoprotein hormones, alpha polypeptide
CLCN6 chloride channel, voltage-sensitive 6
CLDN1 claudin 1
CLDN11 claudin 11
COQ7 coenzyme Q7 homolog, ubiquinone (yeast)
CPS1 carbamoyl-phosphate synthase 1, mitochondrial
CTSF cathepsin F
CYSLTR1 cysteinyl leukotriene receptor 1
DDIT3 DNA-damage-inducible transcript 3
DENND2A DENN/MADD domain containing 2A
DEPTOR DEP domain containing MTOR-interacting protein
DMTN dematin actin binding protein
DZIP3 DAZ interacting zinc finger protein 3
EFNA3 ephrin-A3
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific )
ENOX1 ecto-NOX disulfide-thiol exchanger 1
ERN2 endoplasmic reticulum to nucleus signaling 2
ETNK2 ethanolamine kinase 2
FLT4 fms-related tyrosine kinase 4
FXR2 fragile X mental retardation, autosomal homolog 2
GAD1 glutamate decarboxylase 1 (brain, 67kDa)
GRAMD1C GRAM domain containing 1C
HAMP hepcidin antimicrobial peptide
HCFC1 host cell factor C1
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
HOXA1 homeobox A1
IGL immunoglobulin lambda locus
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IMPG2 interphotoreceptor matrix proteoglycan 2
ITFG2 integrin alpha FG-GAP repeat containing 2
KCNJ8 potassium channel, inwardly rectifying subfamily J, member 8
KLHL36 kelch-like family member 36
LAX1 lymphocyte transmembrane adaptor 1
LDLRAD4 low density lipoprotein receptor class A domain containing 4
LINC00597 long intergenic non-protein coding RNA 597
LMF1 lipase maturation factor 1
LOXL3 lysyl oxidase-like 3
LPAR6 lysophosphatidic acid receptor 6
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2
MOCS1 molybdenum cofactor synthesis 1
MTAP methylthioadenosine phosphorylase
NDUFB7 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein
NPEPL1 aminopeptidase-like 1
NT5M 5',3'-nucleotidase, mitochondrial
NTSR1 neurotensin receptor 1 (high affinity)
OGFR opioid growth factor receptor
PDE8B phosphodiesterase 8B
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PHF7 PHD finger protein 7
PHLDB1 pleckstrin homology-like domain, family B, member 1
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PIN1P1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 pseudogene 1
PRICKLE3 prickle homolog 3 (Drosophila)
PTPN18 protein tyrosine phosphatase, non-receptor type 18 (brain-derived)
PTPN21 protein tyrosine phosphatase, non-receptor type 21
RAB31 RAB31, member RAS oncogene family
RABGGTA Rab geranylgeranyltransferase, alpha subunit
RAD54L2 RAD54-like 2 (S. cerevisiae)
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
RPL10 ribosomal protein L10
RWDD2A RWD domain containing 2A
SCNN1G sodium channel, non voltage gated 1 gamma subunit
SEC24D SEC24 family member D
SHROOM2 shroom family member 2
SIRT5 sirtuin 5
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SLC36A1 solute carrier family 36 (proton/amino acid symporter), member 1
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
SPTBN2 spectrin, beta, non-erythrocytic 2
ST6GALNAC4 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4
SUGP1 SURP and G patch domain containing 1
SYK spleen tyrosine kinase
SYNJ2 synaptojanin 2
TBCD tubulin folding cofactor D
TMEM53 transmembrane protein 53
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TOR1AIP1 torsin A interacting protein 1
TRABD TraB domain containing
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
WAS Wiskott-Aldrich syndrome
WIPI2 WD repeat domain, phosphoinositide interacting 2

decreased expression

Symbol Name
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3
ABHD8 abhydrolase domain containing 8
AMBRA1 autophagy/beclin-1 regulator 1
ANAPC2 anaphase promoting complex subunit 2
ANKEF1 ankyrin repeat and EF-hand domain containing 1
ARHGAP10 Rho GTPase activating protein 10
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2
BGLAP bone gamma-carboxyglutamate (gla) protein
BTF3P12 basic transcription factor 3 pseudogene 12
C16ORF59 chromosome 16 open reading frame 59
C1QTNF1 C1q and tumor necrosis factor related protein 1
CCS copper chaperone for superoxide dismutase
CDADC1 cytidine and dCMP deaminase domain containing 1
CDH3 cadherin 3, type 1, P-cadherin (placental)
CDK3 cyclin-dependent kinase 3
CFAP44 cilia and flagella associated protein 44
CHML choroideremia-like (Rab escort protein 2)
CIDEC cell death-inducing DFFA-like effector c
CNTNAP1 contactin associated protein 1
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1
DTX4 deltex 4, E3 ubiquitin ligase
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
ELP3 elongator acetyltransferase complex subunit 3
EPPK1 epiplakin 1
FAM53B family with sequence similarity 53, member B
FKBPL FK506 binding protein like
FMO4 flavin containing monooxygenase 4
GAL3ST4 galactose-3-O-sulfotransferase 4
GJC1 gap junction protein, gamma 1, 45kDa
GLCE glucuronic acid epimerase
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GPRASP1 G protein-coupled receptor associated sorting protein 1
GRAMD4 GRAM domain containing 4
GUF1 GUF1 GTPase homolog (S. cerevisiae)
HIST1H1D histone cluster 1, H1d
HIST1H2AJ histone cluster 1, H2aj
HIST1H2BJ histone cluster 1, H2bj
HIST1H3B histone cluster 1, H3b
HIVEP1 human immunodeficiency virus type I enhancer binding protein 1
HJURP Holliday junction recognition protein
HOXC10 homeobox C10
HP1BP3 heterochromatin protein 1, binding protein 3
IDI2-AS1 IDI2 antisense RNA 1
IFNAR1 interferon (alpha, beta and omega) receptor 1
IGFLR1 IGF-like family receptor 1
KIF18A kinesin family member 18A
KLHL12 kelch-like family member 12
LNPEP leucyl/cystinyl aminopeptidase
LOC100286895 cell division cycle 27 homolog pseudogene
LOC730101 uncharacterized LOC730101
LRFN3 leucine rich repeat and fibronectin type III domain containing 3
MAMLD1 mastermind-like domain containing 1
MEIS1 Meis homeobox 1
METTL4 methyltransferase like 4
MTHFS 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase)
MUC7 mucin 7, secreted
NCS1 neuronal calcium sensor 1
NDP Norrie disease (pseudoglioma)
NPM3 nucleophosmin/nucleoplasmin 3
NR2C2 nuclear receptor subfamily 2, group C, member 2
OTUD3 OTU deubiquitinase 3
PCYT2 phosphate cytidylyltransferase 2, ethanolamine
PDE12 phosphodiesterase 12
PDGFRL platelet-derived growth factor receptor-like
PDLIM2 PDZ and LIM domain 2 (mystique)
PILRB paired immunoglobin-like type 2 receptor beta
PLEKHA6 pleckstrin homology domain containing, family A member 6
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit
PPWD1 peptidylprolyl isomerase domain and WD repeat containing 1
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)
PTPN9 protein tyrosine phosphatase, non-receptor type 9
RNF2 ring finger protein 2
RNF31 ring finger protein 31
SARS2 seryl-tRNA synthetase 2, mitochondrial
SCD5 stearoyl-CoA desaturase 5
SDC3 syndecan 3
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5
SLC25A28 solute carrier family 25 (mitochondrial iron transporter), member 28
SMAD7 SMAD family member 7
STAC SH3 and cysteine rich domain
STAG3 stromal antigen 3
SYNPO synaptopodin
TAOK1 TAO kinase 1
TCIRG1 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3
TENM4 teneurin transmembrane protein 4
TMEM2 transmembrane protein 2
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
TTI2 TELO2 interacting protein 2
TUBA3D tubulin, alpha 3d
USPL1 ubiquitin specific peptidase like 1
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial
ZFYVE16 zinc finger, FYVE domain containing 16
ZNF205 zinc finger protein 205
ZNF254 zinc finger protein 254
ZNF358 zinc finger protein 358
ZNF862 zinc finger protein 862