verapamil Gene Set

Dataset Guide to Pharmacology Chemical Ligands of Receptors
Category physical interactions
Type ligand (chemical)
Description A racemate comprising equimolar amounts of dexverapamil and (S)-verapamil. An L-type calcium channel blocker of the phenylalkylamine class, it is used (particularly as the hydrochloride salt) in the treatment of hypertension, angina pectoris and cardiac arrhythmia, and as a preventive medication for migraine. (Chemical Entities of Biological Interest Ontology, CHEBI_9948)
External Link http://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=2406
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Genes

10 receptors of the verapamil ligand (chemical) from the curated Guide to Pharmacology Chemical Ligands of Receptors dataset.

Symbol Name
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit
CACNA1F calcium channel, voltage-dependent, L type, alpha 1F subunit
CACNA1S calcium channel, voltage-dependent, L type, alpha 1S subunit
KCNA10 potassium channel, voltage gated shaker related subfamily A, member 10
KCNA7 potassium channel, voltage gated shaker related subfamily A, member 7
KCNC2 potassium channel, voltage gated Shaw related subfamily C, member 2
KCNJ6 potassium channel, inwardly rectifying subfamily J, member 6
NALCN sodium leak channel, non selective
SLC29A4 solute carrier family 29 (equilibrative nucleoside transporter), member 4