vesicoureteral reflux Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores
Category disease or phenotype associations
Type disease
Description A ureteral disease characterized by backward flow of urine from the urinary bladder into the ureter. (Human Disease Ontology, DOID_9620)
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Genes

130 genes co-occuring with the disease vesicoureteral reflux in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
TMEM173 transmembrane protein 173 2.37886
UPK3A uroplakin 3A 1.88482
ROBO2 roundabout, axon guidance receptor, homolog 2 (Drosophila) 1.7496
UPK1B uroplakin 1B 1.71499
SCIN scinderin 1.64756
MEOX2 mesenchyme homeobox 2 1.55336
UPK1A uroplakin 1A 1.46451
PAX2 paired box 2 1.46276
PMS2P1 postmeiotic segregation increased 2 pseudogene 1 1.33065
AGTR2 angiotensin II receptor, type 2 1.26778
UBTD2 ubiquitin domain containing 2 1.22605
UPK2 uroplakin 2 1.21912
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1 1.17121
FGFRL1 fibroblast growth factor receptor-like 1 1.13755
PALM paralemmin 1.11982
REN renin 1.06144
ZCCHC14 zinc finger, CCHC domain containing 14 1.05807
FBXW11 F-box and WD repeat domain containing 11 0.990644
IP6K1 inositol hexakisphosphate kinase 1 0.941611
EMX2 empty spiracles homeobox 2 0.916787
CRP C-reactive protein, pentraxin-related 0.88434
B2M beta-2-microglobulin 0.876557
RANBP17 RAN binding protein 17 0.865912
ACE angiotensin I converting enzyme 0.862637
IP6K2 inositol hexakisphosphate kinase 2 0.825358
HPSE2 heparanase 2 (inactive) 0.790492
TNXB tenascin XB 0.777386
TNXA tenascin XA (pseudogene) 0.76921
NSD1 nuclear receptor binding SET domain protein 1 0.763902
EYA1 EYA transcriptional coactivator and phosphatase 1 0.760639
GLMN glomulin, FKBP associated protein 0.756971
CXCL8 chemokine (C-X-C motif) ligand 8 0.72612
HIAT1 hippocampus abundant transcript 1 0.718039
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila) 0.718039
LAX1 lymphocyte transmembrane adaptor 1 0.708767
CDC5L cell division cycle 5-like 0.687491
SALL2 spalt-like transcription factor 2 0.668742
CTDSP2 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2 0.653276
F3 coagulation factor III (thromboplastin, tissue factor) 0.652089
LRIG2 leucine-rich repeats and immunoglobulin-like domains 2 0.640251
CXCR1 chemokine (C-X-C motif) receptor 1 0.638676
NDUFA9 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39kDa 0.623751
FOXL1 forkhead box L1 0.619442
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) 0.615138
FGF10 fibroblast growth factor 10 0.59991
CDK2AP1 cyclin-dependent kinase 2 associated protein 1 0.595233
TGFB1 transforming growth factor, beta 1 0.557509
SH2B1 SH2B adaptor protein 1 0.549359
FGFR2 fibroblast growth factor receptor 2 0.539667
ALB albumin 0.538506
GDNF glial cell derived neurotrophic factor 0.521502
MN1 meningioma (disrupted in balanced translocation) 1 0.516879
PIDD1 p53-induced death domain protein 1 0.512648
GLI3 GLI family zinc finger 3 0.510728
UCN urocortin 0.50689
CRNN cornulin 0.490072
GFRA1 GDNF family receptor alpha 1 0.484364
CELSR3 cadherin, EGF LAG seven-pass G-type receptor 3 0.482844
KAT8 K(lysine) acetyltransferase 8 0.472604
RET ret proto-oncogene 0.461639
CST3 cystatin C 0.45447
TST thiosulfate sulfurtransferase (rhodanese) 0.451078
UMOD uromodulin 0.440914
FBXL20 F-box and leucine-rich repeat protein 20 0.434524
TIAF1 TGFB1-induced anti-apoptotic factor 1 0.429642
ARX aristaless related homeobox 0.42739
MEA1 male-enhanced antigen 1 0.421016
TLX3 T-cell leukemia homeobox 3 0.414276
GREM1 gremlin 1, DAN family BMP antagonist 0.409787
HMBS hydroxymethylbilane synthase 0.409414
SGCE sarcoglycan, epsilon 0.405305
SALL1 spalt-like transcription factor 1 0.402318
CABIN1 calcineurin binding protein 1 0.393746
WNT11 wingless-type MMTV integration site family, member 11 0.389281
POLK polymerase (DNA directed) kappa 0.386308
IL6 interleukin 6 0.379997
HES2 hes family bHLH transcription factor 2 0.374438
SIX2 SIX homeobox 2 0.371107
FGF7 fibroblast growth factor 7 0.369628
TFCP2 transcription factor CP2 0.367779
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1 0.351187
CFL1 cofilin 1 (non-muscle) 0.350452
EN1 engrailed homeobox 1 0.349349
CHD1L chromodomain helicase DNA binding protein 1-like 0.343106
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 0.339073
CLEC3B C-type lectin domain family 3, member B 0.321181
SIX5 SIX homeobox 5 0.320454
RAPGEF1 Rap guanine nucleotide exchange factor (GEF) 1 0.316456
FLNB filamin B, beta 0.307757
TREX1 three prime repair exonuclease 1 0.296211
ASPN asporin 0.291898
BMP4 bone morphogenetic protein 4 0.287952
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein 0.287235
APOL1 apolipoprotein L, 1 0.284728
SCNN1G sodium channel, non voltage gated 1 gamma subunit 0.284371
AGTR1 angiotensin II receptor, type 1 0.280082
FOXC2 forkhead box C2 0.272241
LCN2 lipocalin 2 0.271886
MYO18A myosin XVIIIA 0.26514
FN1 fibronectin 1 0.256652
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 0.247852
ACAN aggrecan 0.244696
NFIA nuclear factor I/A 0.240847
ELAVL3 ELAV like neuron-specific RNA binding protein 3 0.238054
TLR6 toll-like receptor 6 0.233183
CD79A CD79a molecule, immunoglobulin-associated alpha 0.227988
F13A1 coagulation factor XIII, A1 polypeptide 0.227988
CPN1 carboxypeptidase N, polypeptide 1 0.226952
GNB3 guanine nucleotide binding protein (G protein), beta polypeptide 3 0.222136
IFNGR1 interferon gamma receptor 1 0.215992
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1 0.215653
EDN1 endothelin 1 0.208579
WEE1 WEE1 G2 checkpoint kinase 0.206913
CASP6 caspase 6, apoptosis-related cysteine peptidase 0.205916
GPR182 G protein-coupled receptor 182 0.205254
FRZB frizzled-related protein 0.20229
MAP1LC3B microtubule-associated protein 1 light chain 3 beta 0.201308
TIMP1 TIMP metallopeptidase inhibitor 1 0.200982
EP300 E1A binding protein p300 0.188632
NCOA2 nuclear receptor coactivator 2 0.18591
FGFR1 fibroblast growth factor receptor 1 0.180367
ICK intestinal cell (MAK-like) kinase 0.177851
GLO1 glyoxalase I 0.176215
FGF8 fibroblast growth factor 8 (androgen-induced) 0.175411
HAVCR1 hepatitis A virus cellular receptor 1 0.173057
ANOS1 anosmin 1 0.172799
SGCA sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein) 0.166544
TNF tumor necrosis factor 0.162707
IL4R interleukin 4 receptor 0.162306
AQP1 aquaporin 1 (Colton blood group) 0.160387