| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the vigabatrin-5415 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCA7 | ATP-binding cassette, sub-family A (ABC1), member 7 |
| ADAM8 | ADAM metallopeptidase domain 8 |
| AGFG1 | ArfGAP with FG repeats 1 |
| AP5Z1 | adaptor-related protein complex 5, zeta 1 subunit |
| APBA2 | amyloid beta (A4) precursor protein-binding, family A, member 2 |
| APOC1 | apolipoprotein C-I |
| AQP3 | aquaporin 3 (Gill blood group) |
| ARNT | aryl hydrocarbon receptor nuclear translocator |
| BAIAP3 | BAI1-associated protein 3 |
| BTN2A2 | butyrophilin, subfamily 2, member A2 |
| C1ORF105 | chromosome 1 open reading frame 105 |
| CACNA1D | calcium channel, voltage-dependent, L type, alpha 1D subunit |
| CAMK2G | calcium/calmodulin-dependent protein kinase II gamma |
| CCPG1 | cell cycle progression 1 |
| CD34 | CD34 molecule |
| CDC5L | cell division cycle 5-like |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) |
| CHST3 | carbohydrate (chondroitin 6) sulfotransferase 3 |
| CLCN4 | chloride channel, voltage-sensitive 4 |
| CLCN7 | chloride channel, voltage-sensitive 7 |
| COL11A2 | collagen, type XI, alpha 2 |
| CREBZF | CREB/ATF bZIP transcription factor |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 |
| DIAPH2-AS1 | DIAPH2 antisense RNA 1 |
| DLC1 | DLC1 Rho GTPase activating protein |
| DYM | dymeclin |
| EFNB3 | ephrin-B3 |
| FDX1 | ferredoxin 1 |
| FEZ1 | fasciculation and elongation protein zeta 1 (zygin I) |
| FGFR3 | fibroblast growth factor receptor 3 |
| FSTL3 | follistatin-like 3 (secreted glycoprotein) |
| GLIPR1 | GLI pathogenesis-related 1 |
| GRAMD1C | GRAM domain containing 1C |
| GRM8 | glutamate receptor, metabotropic 8 |
| HFE | hemochromatosis |
| HPX | hemopexin |
| HTN3 | histatin 3 |
| IFIT5 | interferon-induced protein with tetratricopeptide repeats 5 |
| IL1RAP | interleukin 1 receptor accessory protein |
| INHBE | inhibin, beta E |
| ITIH2 | inter-alpha-trypsin inhibitor heavy chain 2 |
| ITPKB | inositol-trisphosphate 3-kinase B |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 |
| KLHL29 | kelch-like family member 29 |
| KRT17 | keratin 17, type I |
| LMAN1 | lectin, mannose-binding, 1 |
| LRP12 | low density lipoprotein receptor-related protein 12 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 |
| LY6G6C | lymphocyte antigen 6 complex, locus G6C |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MBD2 | methyl-CpG binding domain protein 2 |
| MBD3 | methyl-CpG binding domain protein 3 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase |
| MIER2 | mesoderm induction early response 1, family member 2 |
| MMP3 | matrix metallopeptidase 3 |
| MPDZ | multiple PDZ domain protein |
| MSX2 | msh homeobox 2 |
| NBEAL2 | neurobeachin-like 2 |
| NOS1 | nitric oxide synthase 1 (neuronal) |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) |
| NRP1 | neuropilin 1 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 |
| PDE3B | phosphodiesterase 3B, cGMP-inhibited |
| PIDD1 | p53-induced death domain protein 1 |
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| PLK3 | polo-like kinase 3 |
| PLK4 | polo-like kinase 4 |
| POU4F1 | POU class 4 homeobox 1 |
| PPARA | peroxisome proliferator-activated receptor alpha |
| PRRC2B | proline-rich coiled-coil 2B |
| PTBP3 | polypyrimidine tract binding protein 3 |
| PTN | pleiotrophin |
| RBBP4 | retinoblastoma binding protein 4 |
| RPL10L | ribosomal protein L10-like |
| SERPINA7 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7 |
| SGK2 | serum/glucocorticoid regulated kinase 2 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 |
| SLC9A8 | solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8 |
| SOGA1 | suppressor of glucose, autophagy associated 1 |
| SOX30 | SRY (sex determining region Y)-box 30 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 |
| TAP2 | transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) |
| TAPBP | TAP binding protein (tapasin) |
| TBL2 | transducin (beta)-like 2 |
| TCF3 | transcription factor 3 |
| TCP10 | t-complex 10 |
| TGFB2 | transforming growth factor, beta 2 |
| TGFBR1 | transforming growth factor, beta receptor 1 |
| TP53I11 | tumor protein p53 inducible protein 11 |
| TPMT | thiopurine S-methyltransferase |
| TRAF3IP2 | TRAF3 interacting protein 2 |
| TTF2 | transcription termination factor, RNA polymerase II |
| UBE2D4 | ubiquitin-conjugating enzyme E2D 4 (putative) |
| UPP1 | uridine phosphorylase 1 |
| USB1 | U6 snRNA biogenesis 1 |
| WIZ | widely interspaced zinc finger motifs |
| ZNF79 | zinc finger protein 79 |
| Symbol | Name |
|---|---|
| ACTL8 | actin-like 8 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) |
| AKR1C2 | aldo-keto reductase family 1, member C2 |
| APOD | apolipoprotein D |
| C1ORF35 | chromosome 1 open reading frame 35 |
| CAMK1 | calcium/calmodulin-dependent protein kinase I |
| CAMK4 | calcium/calmodulin-dependent protein kinase IV |
| CCDC85C | coiled-coil domain containing 85C |
| CCZ1B | CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae) |
| CDK3 | cyclin-dependent kinase 3 |
| CLCN2 | chloride channel, voltage-sensitive 2 |
| CLIC2 | chloride intracellular channel 2 |
| CORT | cortistatin |
| CRIP1 | cysteine-rich protein 1 (intestinal) |
| CYP4F11 | cytochrome P450, family 4, subfamily F, polypeptide 11 |
| DAPP1 | dual adaptor of phosphotyrosine and 3-phosphoinositides |
| DGAT1 | diacylglycerol O-acyltransferase 1 |
| DNAH17 | dynein, axonemal, heavy chain 17 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| ETV6 | ets variant 6 |
| FAM46C | family with sequence similarity 46, member C |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| GADD45G | growth arrest and DNA-damage-inducible, gamma |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) |
| GNG7 | guanine nucleotide binding protein (G protein), gamma 7 |
| GSTTP1 | glutathione S-transferase theta pseudogene 1 |
| HIST1H2AK | histone cluster 1, H2ak |
| HIST1H4E | histone cluster 1, H4e |
| HOXC5 | homeobox C5 |
| HPN | hepsin |
| IFI27 | interferon, alpha-inducible protein 27 |
| IFI35 | interferon-induced protein 35 |
| INO80D | INO80 complex subunit D |
| ITGAL | integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) |
| KIF13B | kinesin family member 13B |
| KLF2 | Kruppel-like factor 2 |
| LAIR2 | leukocyte-associated immunoglobulin-like receptor 2 |
| LAMP3 | lysosomal-associated membrane protein 3 |
| LOC257152 | uncharacterized LOC257152 |
| MEFV | Mediterranean fever |
| MUL1 | mitochondrial E3 ubiquitin protein ligase 1 |
| MYO1F | myosin IF |
| MYOZ3 | myozenin 3 |
| NCALD | neurocalcin delta |
| NDOR1 | NADPH dependent diflavin oxidoreductase 1 |
| NEUROD4 | neuronal differentiation 4 |
| NKAIN1 | Na+/K+ transporting ATPase interacting 1 |
| NKX3-2 | NK3 homeobox 2 |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| P3H1 | prolyl 3-hydroxylase 1 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 |
| PCDHA6 | protocadherin alpha 6 |
| PDE12 | phosphodiesterase 12 |
| PDE6B | phosphodiesterase 6B, cGMP-specific, rod, beta |
| PGR | progesterone receptor |
| PIK3C2B | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta |
| PORCN | porcupine homolog (Drosophila) |
| PRF1 | perforin 1 (pore forming protein) |
| PSD4 | pleckstrin and Sec7 domain containing 4 |
| PTPRS | protein tyrosine phosphatase, receptor type, S |
| REM1 | RAS (RAD and GEM)-like GTP-binding 1 |
| RFNG | RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase |
| RHBDF2 | rhomboid 5 homolog 2 (Drosophila) |
| RIN1 | Ras and Rab interactor 1 |
| S100A9 | S100 calcium binding protein A9 |
| SAMD9 | sterile alpha motif domain containing 9 |
| SERGEF | secretion regulating guanine nucleotide exchange factor |
| SIGLEC15 | sialic acid binding Ig-like lectin 15 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 |
| SLC25A22 | solute carrier family 25 (mitochondrial carrier: glutamate), member 22 |
| SLC47A1 | solute carrier family 47 (multidrug and toxin extrusion), member 1 |
| SLIT2 | slit homolog 2 (Drosophila) |
| SPTBN5 | spectrin, beta, non-erythrocytic 5 |
| SRD5A3 | steroid 5 alpha-reductase 3 |
| ST5 | suppression of tumorigenicity 5 |
| STK16 | serine/threonine kinase 16 |
| TAB1 | TGF-beta activated kinase 1/MAP3K7 binding protein 1 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa |
| TBC1D17 | TBC1 domain family, member 17 |
| TCEB3B | transcription elongation factor B polypeptide 3B (elongin A2) |
| TNS2 | tensin 2 |
| TRIM25 | tripartite motif containing 25 |
| TRPC5 | transient receptor potential cation channel, subfamily C, member 5 |
| TRPV6 | transient receptor potential cation channel, subfamily V, member 6 |
| TTBK2 | tau tubulin kinase 2 |
| TTC4 | tetratricopeptide repeat domain 4 |
| UNC119 | unc-119 homolog (C. elegans) |
| UNC93B1 | unc-93 homolog B1 (C. elegans) |
| VEGFC | vascular endothelial growth factor C |
| VGF | VGF nerve growth factor inducible |
| VLDLR | very low density lipoprotein receptor |
| WDR62 | WD repeat domain 62 |
| XYLT2 | xylosyltransferase II |
| YIF1B | Yip1 interacting factor homolog B (S. cerevisiae) |
| ZNF10 | zinc finger protein 10 |
| ZNF428 | zinc finger protein 428 |
| ZNF639 | zinc finger protein 639 |
| ZNF862 | zinc finger protein 862 |
