vigabatrin Gene Set

Dataset LINCS L1000 CMAP Chemical Perturbation Consensus Signatures
Category transcriptomics
Type small molecule perturbation
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Genes

12 genes differentially expressed following the vigabatrin small molecule perturbation from the LINCS L1000 CMAP Chemical Perturbation Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
RPS4Y1 ribosomal protein S4, Y-linked 1 5.08977
MALT1 MALT1 paracaspase 3.8369
HMG20B high mobility group 20B 3.36948
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7 3.16548

decreased expression

Symbol Name Standardized Value
XIC X chromosome inactivation center -4.26037
APPBP2 amyloid beta precursor protein (cytoplasmic tail) binding protein 2 -3.61912
VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae) -3.57892
TRAPPC3 trafficking protein particle complex 3 -3.38364
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -3.30509
GSTZ1 glutathione S-transferase zeta 1 -3.10876
GLO1 glyoxalase I -3.07407
CHRNA1 cholinergic receptor, nicotinic, alpha 1 (muscle) -3.03929