vinblastine-7551 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the vinblastine-7551 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
ANKRD12 ankyrin repeat domain 12
APOC1 apolipoprotein C-I
AREG amphiregulin
ARFRP1 ADP-ribosylation factor related protein 1
ARHGAP12 Rho GTPase activating protein 12
ARHGAP29 Rho GTPase activating protein 29
ATF3 activating transcription factor 3
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
ATXN1 ataxin 1
BAX BCL2-associated X protein
BIK BCL2-interacting killer (apoptosis-inducing)
BRD4 bromodomain containing 4
BRE brain and reproductive organ-expressed (TNFRSF1A modulator)
CABIN1 calcineurin binding protein 1
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CDC42EP2 CDC42 effector protein (Rho GTPase binding) 2
CHMP7 charged multivesicular body protein 7
CISH cytokine inducible SH2-containing protein
COL1A1 collagen, type I, alpha 1
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CTNND2 catenin (cadherin-associated protein), delta 2
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DEAF1 DEAF1 transcription factor
DLEU2 deleted in lymphocytic leukemia 2 (non-protein coding)
DOCK1 dedicator of cytokinesis 1
DOCK6 dedicator of cytokinesis 6
DOHH deoxyhypusine hydroxylase/monooxygenase
ECE1 endothelin converting enzyme 1
EMC1 ER membrane protein complex subunit 1
ENC1 ectodermal-neural cortex 1 (with BTB domain)
ENDOD1 endonuclease domain containing 1
ERN2 endoplasmic reticulum to nucleus signaling 2
FAM69A family with sequence similarity 69, member A
FBXL15 F-box and leucine-rich repeat protein 15
FBXO34 F-box protein 34
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
FOXJ2 forkhead box J2
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2
GUF1 GUF1 GTPase homolog (S. cerevisiae)
HSD17B6 hydroxysteroid (17-beta) dehydrogenase 6
IGFBP5 insulin-like growth factor binding protein 5
IRF6 interferon regulatory factor 6
ITSN1 intersectin 1 (SH3 domain protein)
KDSR 3-ketodihydrosphingosine reductase
KIAA0485 uncharacterized LOC57235
KLF4 Kruppel-like factor 4 (gut)
KLF6 Kruppel-like factor 6
LPIN1 lipin 1
LPP LIM domain containing preferred translocation partner in lipoma
LRRC1 leucine rich repeat containing 1
MED14 mediator complex subunit 14
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
NUAK1 NUAK family, SNF1-like kinase, 1
NUBPL nucleotide binding protein-like
PACS1 phosphofurin acidic cluster sorting protein 1
PCSK6 proprotein convertase subtilisin/kexin type 6
PDCL phosducin-like
PDGFA platelet-derived growth factor alpha polypeptide
PER2 period circadian clock 2
PEX12 peroxisomal biogenesis factor 12
PEX26 peroxisomal biogenesis factor 26
PEX7 peroxisomal biogenesis factor 7
PICALM phosphatidylinositol binding clathrin assembly protein
PIGL phosphatidylinositol glycan anchor biosynthesis, class L
PINK1 PTEN induced putative kinase 1
PKNOX1 PBX/knotted 1 homeobox 1
PLXND1 plexin D1
POLI polymerase (DNA directed) iota
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PTEN phosphatase and tensin homolog
PUM1 pumilio RNA-binding family member 1
RAB11FIP2 RAB11 family interacting protein 2 (class I)
RAI14 retinoic acid induced 14
RNF25 ring finger protein 25
SAMD4A sterile alpha motif domain containing 4A
SCARB2 scavenger receptor class B, member 2
SEC22A SEC22 vesicle trafficking protein homolog A (S. cerevisiae)
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SMA4 glucuronidase, beta pseudogene
SMTN smoothelin
SNORA21 small nucleolar RNA, H/ACA box 21
SOGA1 suppressor of glucose, autophagy associated 1
SYNGR3 synaptogyrin 3
TET3 tet methylcytosine dioxygenase 3
TGIF2 TGFB-induced factor homeobox 2
TMEM2 transmembrane protein 2
TNFAIP8 tumor necrosis factor, alpha-induced protein 8
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TRAPPC10 trafficking protein particle complex 10
UBE2L3 ubiquitin-conjugating enzyme E2L 3
URGCP upregulator of cell proliferation
WASF2 WAS protein family, member 2
WRN Werner syndrome, RecQ helicase-like
ZC3H12A zinc finger CCCH-type containing 12A
ZNF174 zinc finger protein 174

decreased expression

Symbol Name
A1CF APOBEC1 complementation factor
ADGRE5 adhesion G protein-coupled receptor E5
AEBP1 AE binding protein 1
AKR1C3 aldo-keto reductase family 1, member C3
ALOX12P2 arachidonate 12-lipoxygenase pseudogene 2
ALS2CL ALS2 C-terminal like
ARMC6 armadillo repeat containing 6
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
BBS10 Bardet-Biedl syndrome 10
BRAF B-Raf proto-oncogene, serine/threonine kinase
C6ORF47 chromosome 6 open reading frame 47
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CBX8 chromobox homolog 8
CCBL1 cysteine conjugate-beta lyase, cytoplasmic
CDT1 chromatin licensing and DNA replication factor 1
CHRNA9 cholinergic receptor, nicotinic, alpha 9 (neuronal)
CHST7 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7
CNPY3 canopy FGF signaling regulator 3
CRY2 cryptochrome circadian clock 2
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DBR1 debranching RNA lariats 1
DDX4 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4
DNAL4 dynein, axonemal, light chain 4
ERC2-IT1 ERC2 intronic transcript 1
FKSG49 FKSG49
FLCN folliculin
FOSL1 FOS-like antigen 1
GEM GTP binding protein overexpressed in skeletal muscle
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GPR182 G protein-coupled receptor 182
GRTP1 growth hormone regulated TBC protein 1
HIST1H2AI histone cluster 1, H2ai
HS1BP3 HCLS1 binding protein 3
HSPB6 heat shock protein, alpha-crystallin-related, B6
IFI6 interferon, alpha-inducible protein 6
IL12RB1 interleukin 12 receptor, beta 1
IRF2BP1 interferon regulatory factor 2 binding protein 1
JAM2 junctional adhesion molecule 2
KCNMB4 potassium channel subfamily M regulatory beta subunit 4
KLHL25 kelch-like family member 25
L2HGDH L-2-hydroxyglutarate dehydrogenase
LINC00339 long intergenic non-protein coding RNA 339
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
MATK megakaryocyte-associated tyrosine kinase
MEP1B meprin A, beta
MMP13 matrix metallopeptidase 13
MORC3 MORC family CW-type zinc finger 3
MPP6 membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)
MSI1 musashi RNA-binding protein 1
NUPL2 nucleoporin like 2
NXPH3 neurexophilin 3
OPHN1 oligophrenin 1
PAX1 paired box 1
PBLD phenazine biosynthesis-like protein domain containing
PCDHB3 protocadherin beta 3
PDZD8 PDZ domain containing 8
PIGN phosphatidylinositol glycan anchor biosynthesis, class N
PLEKHA6 pleckstrin homology domain containing, family A member 6
PODNL1 podocan-like 1
PRMT7 protein arginine methyltransferase 7
RAB40C RAB40C, member RAS oncogene family
RBM41 RNA binding motif protein 41
RCOR3 REST corepressor 3
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RIN1 Ras and Rab interactor 1
RORC RAR-related orphan receptor C
RPRM reprimo, TP53 dependent G2 arrest mediator candidate
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
SLC50A1 solute carrier family 50 (sugar efflux transporter), member 1
SNHG3 small nucleolar RNA host gene 3
SP4 Sp4 transcription factor
STRA6 stimulated by retinoic acid 6
TBCCD1 TBCC domain containing 1
TCTN2 tectonic family member 2
TNS2 tensin 2
TUBA3C tubulin, alpha 3c
TUBA3D tubulin, alpha 3d
TUBA4A tubulin, alpha 4a
TUBB tubulin, beta class I
TUBB3 tubulin, beta 3 class III
TUBB4B tubulin, beta 4B class IVb
UBIAD1 UbiA prenyltransferase domain containing 1
UBQLN4 ubiquilin 4
VASP vasodilator-stimulated phosphoprotein
VPS9D1 VPS9 domain containing 1
WNT16 wingless-type MMTV integration site family, member 16
XAF1 XIAP associated factor 1
ZNF180 zinc finger protein 180
ZNF219 zinc finger protein 219
ZNF254 zinc finger protein 254
ZNF428 zinc finger protein 428
ZNF571 zinc finger protein 571
ZNF586 zinc finger protein 586
ZNF778 zinc finger protein 778