vinburnine-1788 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the vinburnine-1788 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAM8 ADAM metallopeptidase domain 8
AFF2 AF4/FMR2 family, member 2
AGRN agrin
AIM2 absent in melanoma 2
ALDOB aldolase B, fructose-bisphosphate
ANKMY1 ankyrin repeat and MYND domain containing 1
ASB13 ankyrin repeat and SOCS box containing 13
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
C19ORF66 chromosome 19 open reading frame 66
C22ORF29 chromosome 22 open reading frame 29
CACNG4 calcium channel, voltage-dependent, gamma subunit 4
CD59 CD59 molecule, complement regulatory protein
CDHR2 cadherin-related family member 2
CETN1 centrin, EF-hand protein, 1
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like
CTPS2 CTP synthase 2
CTRB2 chymotrypsinogen B2
DGCR8 DGCR8 microprocessor complex subunit
DUS2 dihydrouridine synthase 2
DUSP13 dual specificity phosphatase 13
DXO decapping exoribonuclease
DYRK2 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
EFNB3 ephrin-B3
ELMO2 engulfment and cell motility 2
EP400 E1A binding protein p400
ERO1L ERO1-like (S. cerevisiae)
FAM102A family with sequence similarity 102, member A
FSCN3 fascin actin-bundling protein 3, testicular
GAP43 growth associated protein 43
GCDH glutaryl-CoA dehydrogenase
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GLTSCR1L GLTSCR1-like
GNB3 guanine nucleotide binding protein (G protein), beta polypeptide 3
GPATCH3 G patch domain containing 3
GPR107 G protein-coupled receptor 107
GYPB glycophorin B (MNS blood group)
HBB hemoglobin, beta
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HIPK3 homeodomain interacting protein kinase 3
HLA-DOA major histocompatibility complex, class II, DO alpha
HMGB3P1 high mobility group box 3 pseudogene 1
HOOK2 hook microtubule-tethering protein 2
HP1BP3 heterochromatin protein 1, binding protein 3
IL1RAP interleukin 1 receptor accessory protein
INTS5 integrator complex subunit 5
IRF2BP1 interferon regulatory factor 2 binding protein 1
ITGA7 integrin, alpha 7
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
KIFC1 kinesin family member C1
KIZ kizuna centrosomal protein
KLK5 kallikrein-related peptidase 5
KRT38 keratin 38, type I
LEFTY2 left-right determination factor 2
LENEP lens epithelial protein
LRRK1 leucine-rich repeat kinase 1
MAGED2 melanoma antigen family D2
MAP4 microtubule-associated protein 4
MAPK10 mitogen-activated protein kinase 10
MTM1 myotubularin 1
MYL10 myosin, light chain 10, regulatory
MYL6 myosin, light chain 6, alkali, smooth muscle and non-muscle
MYOF myoferlin
N4BP2L2 NEDD4 binding protein 2-like 2
NR4A2 nuclear receptor subfamily 4, group A, member 2
NUP62 nucleoporin 62kDa
NXF2 nuclear RNA export factor 2
PCSK6 proprotein convertase subtilisin/kexin type 6
PLTP phospholipid transfer protein
POLR3D polymerase (RNA) III (DNA directed) polypeptide D, 44kDa
PPIEL peptidylprolyl isomerase E-like pseudogene
PSIP1 PC4 and SFRS1 interacting protein 1
PTPRA protein tyrosine phosphatase, receptor type, A
RAB6B RAB6B, member RAS oncogene family
RBFOX2 RNA binding protein, fox-1 homolog (C. elegans) 2
RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis)
RNASE3 ribonuclease, RNase A family, 3
RNF216 ring finger protein 216
RPL18 ribosomal protein L18
SAG S-antigen; retina and pineal gland (arrestin)
SCAMP1 secretory carrier membrane protein 1
SEC23IP SEC23 interacting protein
SF3A2 splicing factor 3a, subunit 2, 66kDa
SH2D3A SH2 domain containing 3A
SKA1 spindle and kinetochore associated complex subunit 1
SLC17A4 solute carrier family 17, member 4
SLPI secretory leukocyte peptidase inhibitor
SPDEF SAM pointed domain containing ETS transcription factor
SUGP1 SURP and G patch domain containing 1
TAOK2 TAO kinase 2
TEX40 testis expressed 40
TPR translocated promoter region, nuclear basket protein
TRIM9 tripartite motif containing 9
TRMT61A tRNA methyltransferase 61A
TRPM3 transient receptor potential cation channel, subfamily M, member 3
ZC3H7B zinc finger CCCH-type containing 7B
ZCCHC14 zinc finger, CCHC domain containing 14
ZMYM6 zinc finger, MYM-type 6
ZNF419 zinc finger protein 419

decreased expression

Symbol Name
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ABCF3 ATP-binding cassette, sub-family F (GCN20), member 3
ABHD17A abhydrolase domain containing 17A
ABT1 activator of basal transcription 1
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
ASTE1 asteroid homolog 1 (Drosophila)
BCL10 B-cell CLL/lymphoma 10
BDH1 3-hydroxybutyrate dehydrogenase, type 1
C11ORF21 chromosome 11 open reading frame 21
C14ORF159 chromosome 14 open reading frame 159
C19ORF24 chromosome 19 open reading frame 24
CCDC25 coiled-coil domain containing 25
CCDC64 coiled-coil domain containing 64
CCNL2 cyclin L2
CD151 CD151 molecule (Raph blood group)
CEP83 centrosomal protein 83kDa
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHCHD7 coiled-coil-helix-coiled-coil-helix domain containing 7
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CISD1 CDGSH iron sulfur domain 1
CKB creatine kinase, brain
CPOX coproporphyrinogen oxidase
CYC1 cytochrome c-1
DEAF1 DEAF1 transcription factor
DEXI Dexi homolog (mouse)
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DONSON downstream neighbor of SON
DPP3 dipeptidyl-peptidase 3
DRD5 dopamine receptor D5
ERCC3 excision repair cross-complementation group 3
ETV6 ets variant 6
F8 coagulation factor VIII, procoagulant component
FAM188A family with sequence similarity 188, member A
FAM222B family with sequence similarity 222, member B
FES FES proto-oncogene, tyrosine kinase
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2
GMPR2 guanosine monophosphate reductase 2
GPATCH1 G patch domain containing 1
GPATCH2 G patch domain containing 2
GPR27 G protein-coupled receptor 27
GTF2F2 general transcription factor IIF, polypeptide 2, 30kDa
H2BFS H2B histone family, member S (pseudogene)
HARS histidyl-tRNA synthetase
HIST1H4C histone cluster 1, H4c
IFRD2 interferon-related developmental regulator 2
INPP5E inositol polyphosphate-5-phosphatase, 72 kDa
IRF2 interferon regulatory factor 2
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit)
KCNK5 potassium channel, two pore domain subfamily K, member 5
KIAA1598
KIFAP3 kinesin-associated protein 3
LACTB2 lactamase, beta 2
LIMD2 LIM domain containing 2
LMBR1L limb development membrane protein 1-like
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LRCH3 leucine-rich repeats and calponin homology (CH) domain containing 3
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MBIP MAP3K12 binding inhibitory protein 1
MCM2 minichromosome maintenance complex component 2
MRPS34 mitochondrial ribosomal protein S34
NADSYN1 NAD synthetase 1
NDUFB6 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa
NME6 NME/NM23 nucleoside diphosphate kinase 6
NRBF2 nuclear receptor binding factor 2
NT5C 5', 3'-nucleotidase, cytosolic
PNRC1 proline-rich nuclear receptor coactivator 1
PPP1R8 protein phosphatase 1, regulatory subunit 8
PRDM13 PR domain containing 13
PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein
RAB11FIP1 RAB11 family interacting protein 1 (class I)
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RPS14P3 ribosomal protein S14 pseudogene 3
RWDD2B RWD domain containing 2B
SARS2 seryl-tRNA synthetase 2, mitochondrial
SDC4 syndecan 4
SDHAF3 succinate dehydrogenase complex assembly factor 3
SELP selectin P (granule membrane protein 140kDa, antigen CD62)
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SIRT6 sirtuin 6
TIMM10 translocase of inner mitochondrial membrane 10 homolog (yeast)
TJP2 tight junction protein 2
TLN1 talin 1
TM7SF2 transmembrane 7 superfamily member 2
TMEM160 transmembrane protein 160
TOE1 target of EGR1, member 1 (nuclear)
TOPORS topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TWF2 twinfilin actin binding protein 2
UBL4A ubiquitin-like 4A
URB2 URB2 ribosome biogenesis 2 homolog (S. cerevisiae)
URGCP upregulator of cell proliferation
USP32 ubiquitin specific peptidase 32
VPS33B vacuolar protein sorting 33 homolog B (yeast)
ZNF175 zinc finger protein 175
ZNF350 zinc finger protein 350
ZNF426 zinc finger protein 426
ZNF536 zinc finger protein 536