vinburnine-2781 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

200 genes differentially expressed following the vinburnine-2781 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAK1 AP2 associated kinase 1
AFF2 AF4/FMR2 family, member 2
ALPPL2 alkaline phosphatase, placental-like 2
ANKRD12 ankyrin repeat domain 12
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
ATF7IP activating transcription factor 7 interacting protein
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2
BAX BCL2-associated X protein
BET1L Bet1 golgi vesicular membrane trafficking protein-like
C10ORF12 chromosome 10 open reading frame 12
C10ORF95 chromosome 10 open reading frame 95
CAMK2G calcium/calmodulin-dependent protein kinase II gamma
CD6 CD6 molecule
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CERS4 ceramide synthase 4
CLTA clathrin, light chain A
COL1A1 collagen, type I, alpha 1
COL6A1 collagen, type VI, alpha 1
COPA coatomer protein complex, subunit alpha
CPB1 carboxypeptidase B1 (tissue)
DDR1-AS1 DDR1 antisense RNA 1 (head to head)
DHRS7 dehydrogenase/reductase (SDR family) member 7
EGFR epidermal growth factor receptor
ERAP1 endoplasmic reticulum aminopeptidase 1
ETV5 ets variant 5
FAM184A family with sequence similarity 184, member A
FBXL7 F-box and leucine-rich repeat protein 7
FFAR2 free fatty acid receptor 2
FGA fibrinogen alpha chain
FH fumarate hydratase
FOSL2 FOS-like antigen 2
GGT1 gamma-glutamyltransferase 1
GLIPR1 GLI pathogenesis-related 1
GPER1 G protein-coupled estrogen receptor 1
GRB7 growth factor receptor-bound protein 7
GRPR gastrin-releasing peptide receptor
HIRA histone cell cycle regulator
HIST1H1D histone cluster 1, H1d
HLA-J major histocompatibility complex, class I, J (pseudogene)
HOMER3 homer scaffolding protein 3
HOXB2 homeobox B2
HOXB7 homeobox B7
HPX hemopexin
IFT140 intraflagellar transport 140
IGKV1D-13 immunoglobulin kappa variable 1D-13
IRF2BP1 interferon regulatory factor 2 binding protein 1
KCNIP1 Kv channel interacting protein 1
KDM4B lysine (K)-specific demethylase 4B
KIFC1 kinesin family member C1
LAT2 linker for activation of T cells family, member 2
LOC157562 uncharacterized LOC157562
LTC4S leukotriene C4 synthase
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
MAGOH2P mago-nashi homolog 2, pseudogene
MAP1A microtubule-associated protein 1A
MAP1S microtubule-associated protein 1S
MBNL2 muscleblind-like splicing regulator 2
MMP11 matrix metallopeptidase 11
MMP25 matrix metallopeptidase 25
MX2 MX dynamin-like GTPase 2
NEK2 NIMA-related kinase 2
NF2 neurofibromin 2 (merlin)
NRF1 nuclear respiratory factor 1
OVOL1 ovo-like zinc finger 1
PAX9 paired box 9
PITX1 paired-like homeodomain 1
PLLP plasmolipin
PPP1R9A protein phosphatase 1, regulatory subunit 9A
QTRT1 queuine tRNA-ribosyltransferase 1
RAB27B RAB27B, member RAS oncogene family
RAB33A RAB33A, member RAS oncogene family
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RETN resistin
RNF122 ring finger protein 122
SCHIP1 schwannomin interacting protein 1
SDC2 syndecan 2
SFTPB surfactant protein B
SH2B1 SH2B adaptor protein 1
SLC16A4 solute carrier family 16, member 4
SLC16A5 solute carrier family 16 (monocarboxylate transporter), member 5
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SNAI2 snail family zinc finger 2
STARD5 StAR-related lipid transfer (START) domain containing 5
STC1 stanniocalcin 1
STRA6 stimulated by retinoic acid 6
SYNJ2 synaptojanin 2
TBC1D2 TBC1 domain family, member 2
TFF2 trefoil factor 2
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TLE4 transducin-like enhancer of split 4
TNFRSF10C tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain
TREX1 three prime repair exonuclease 1
TRIM62 tripartite motif containing 62
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
WIZ widely interspaced zinc finger motifs
ZFP36L1 ZFP36 ring finger protein-like 1
ZFP36L2 ZFP36 ring finger protein-like 2
ZNF506 zinc finger protein 506

decreased expression

Symbol Name
AFAP1 actin filament associated protein 1
AMPD1 adenosine monophosphate deaminase 1
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ASAP1-IT1 ASAP1 intronic transcript 1
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
B9D2 B9 protein domain 2
C1QTNF3 C1q and tumor necrosis factor related protein 3
C2ORF44 chromosome 2 open reading frame 44
C7ORF43 chromosome 7 open reading frame 43
CASZ1 castor zinc finger 1
CBX8 chromobox homolog 8
CCDC9 coiled-coil domain containing 9
CEACAM4 carcinoembryonic antigen-related cell adhesion molecule 4
CHM choroideremia (Rab escort protein 1)
CHRM3 cholinergic receptor, muscarinic 3
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
CNR2 cannabinoid receptor 2 (macrophage)
CORT cortistatin
CPPED1 calcineurin-like phosphoesterase domain containing 1
CPSF7 cleavage and polyadenylation specific factor 7, 59kDa
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
DNALI1 dynein, axonemal, light intermediate chain 1
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DOC2A double C2-like domains, alpha
DSCAM Down syndrome cell adhesion molecule
ETNK2 ethanolamine kinase 2
F3 coagulation factor III (thromboplastin, tissue factor)
FAM212B family with sequence similarity 212, member B
FBXL6 F-box and leucine-rich repeat protein 6
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GK3P glycerol kinase 3 pseudogene
GLS2 glutaminase 2 (liver, mitochondrial)
GLTSCR1 glioma tumor suppressor candidate region gene 1
GPR19 G protein-coupled receptor 19
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HIST1H4D histone cluster 1, H4d
IPO13 importin 13
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KDM5C lysine (K)-specific demethylase 5C
KIAA0125 KIAA0125
KLF3 Kruppel-like factor 3 (basic)
KRI1 KRI1 homolog (S. cerevisiae)
LHX6 LIM homeobox 6
LIN7B lin-7 homolog B (C. elegans)
LINC00115 long intergenic non-protein coding RNA 115
LRRC61 leucine rich repeat containing 61
LYPD3 LY6/PLAUR domain containing 3
MAMLD1 mastermind-like domain containing 1
MEIS1 Meis homeobox 1
MTCP1 mature T-cell proliferation 1
NACA2 nascent polypeptide-associated complex alpha subunit 2
NCALD neurocalcin delta
NIPAL2 NIPA-like domain containing 2
NOL12 nucleolar protein 12
NPFFR1 neuropeptide FF receptor 1
NT5DC3 5'-nucleotidase domain containing 3
OSMR oncostatin M receptor
PIGZ phosphatidylinositol glycan anchor biosynthesis, class Z
PLA2G15 phospholipase A2, group XV
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLCD1 phospholipase C, delta 1
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1
RAB30 RAB30, member RAS oncogene family
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
RPL13P5 ribosomal protein L13 pseudogene 5
RRAGB Ras-related GTP binding B
RUNDC3B RUN domain containing 3B
SAYSD1 SAYSVFN motif domain containing 1
SCRN3 secernin 3
SENP7 SUMO1/sentrin specific peptidase 7
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1
SLMO1 slowmo homolog 1 (Drosophila)
SP1 Sp1 transcription factor
SUPT5H suppressor of Ty 5 homolog (S. cerevisiae)
SYBU syntabulin (syntaxin-interacting)
TBC1D17 TBC1 domain family, member 17
TBC1D19 TBC1 domain family, member 19
THBS3 thrombospondin 3
TICAM1 toll-like receptor adaptor molecule 1
TMEM209 transmembrane protein 209
TOE1 target of EGR1, member 1 (nuclear)
TSPYL2 TSPY-like 2
TTLL1 tubulin tyrosine ligase-like family member 1
VAX2 ventral anterior homeobox 2
VEGFC vascular endothelial growth factor C
WASF1 WAS protein family, member 1
WDR25 WD repeat domain 25
ZBTB39 zinc finger and BTB domain containing 39
ZBTB48 zinc finger and BTB domain containing 48
ZNF205 zinc finger protein 205
ZNF408 zinc finger protein 408
ZNF428 zinc finger protein 428
ZNF571 zinc finger protein 571
ZNF574 zinc finger protein 574
ZNF862 zinc finger protein 862
ZSCAN2 zinc finger and SCAN domain containing 2