vinburnine-7154 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the vinburnine-7154 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
ADM adrenomedullin
AFAP1 actin filament associated protein 1
ALDH1B1 aldehyde dehydrogenase 1 family, member B1
AMIGO2 adhesion molecule with Ig-like domain 2
APLP2 amyloid beta (A4) precursor-like protein 2
ARAP2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
BAG4 BCL2-associated athanogene 4
BIRC3 baculoviral IAP repeat containing 3
BRF1 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit
BRIP1 BRCA1 interacting protein C-terminal helicase 1
C7ORF43 chromosome 7 open reading frame 43
C9ORF156 chromosome 9 open reading frame 156
CD83 CD83 molecule
CDK17 cyclin-dependent kinase 17
CLEC2B C-type lectin domain family 2, member B
CLN8 ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)
COL5A1 collagen, type V, alpha 1
CTGF connective tissue growth factor
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL2 chemokine (C-X-C motif) ligand 2
CXCL3 chemokine (C-X-C motif) ligand 3
CXCL6 chemokine (C-X-C motif) ligand 6
CXCL8 chemokine (C-X-C motif) ligand 8
CYR61 cysteine-rich, angiogenic inducer, 61
DENND3 DENN/MADD domain containing 3
DTNA dystrobrevin, alpha
DUSP1 dual specificity phosphatase 1
EIF4A1 eukaryotic translation initiation factor 4A1
EVI5 ecotropic viral integration site 5
FGF5 fibroblast growth factor 5
FKBP10 FK506 binding protein 10, 65 kDa
FST follistatin
GAD1 glutamate decarboxylase 1 (brain, 67kDa)
GADD45B growth arrest and DNA-damage-inducible, beta
GLIPR1 GLI pathogenesis-related 1
GOLGA8A golgin A8 family, member A
GPR176 G protein-coupled receptor 176
GPRC5B G protein-coupled receptor, class C, group 5, member B
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4
HHEX hematopoietically expressed homeobox
HIC2 hypermethylated in cancer 2
HIST1H1D histone cluster 1, H1d
HOMER3 homer scaffolding protein 3
ICAM1 intercellular adhesion molecule 1
IFT74 intraflagellar transport 74
IL18 interleukin 18
IL6ST interleukin 6 signal transducer
INHBA inhibin, beta A
JUNB jun B proto-oncogene
KIAA0754 KIAA0754
KLF6 Kruppel-like factor 6
KLF7 Kruppel-like factor 7 (ubiquitous)
KRIT1 KRIT1, ankyrin repeat containing
LGR5 leucine-rich repeat containing G protein-coupled receptor 5
LIN37 lin-37 DREAM MuvB core complex component
MAPK14 mitogen-activated protein kinase 14
MCL1 myeloid cell leukemia 1
MDFIC MyoD family inhibitor domain containing
MMP13 matrix metallopeptidase 13
NAB1 NGFI-A binding protein 1 (EGR1 binding protein 1)
NAV3 neuron navigator 3
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
NOLC1 nucleolar and coiled-body phosphoprotein 1
NPM3 nucleophosmin/nucleoplasmin 3
PDE1C phosphodiesterase 1C, calmodulin-dependent 70kDa
PDLIM2 PDZ and LIM domain 2 (mystique)
POLR2D polymerase (RNA) II (DNA directed) polypeptide D
PTX3 pentraxin 3, long
RAB40B RAB40B, member RAS oncogene family
SAP30 Sin3A-associated protein, 30kDa
SCARB1 scavenger receptor class B, member 1
SEC14L1 SEC14-like 1 (S. cerevisiae)
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SIK3 SIK family kinase 3
SLC16A7 solute carrier family 16 (monocarboxylate transporter), member 7
SNAPC1 small nuclear RNA activating complex, polypeptide 1, 43kDa
SOAT1 sterol O-acyltransferase 1
SOCS2 suppressor of cytokine signaling 2
SOS2 son of sevenless homolog 2 (Drosophila)
SPATA2L spermatogenesis associated 2-like
SRD5A3 steroid 5 alpha-reductase 3
STAM2 signal transducing adaptor molecule (SH3 domain and ITAM motif) 2
SYT1 synaptotagmin I
TGFB2 transforming growth factor, beta 2
THBS1 thrombospondin 1
TK2 thymidine kinase 2, mitochondrial
TMC7 transmembrane channel-like 7
TMCC1 transmembrane and coiled-coil domain family 1
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TRAPPC10 trafficking protein particle complex 10
TRIO trio Rho guanine nucleotide exchange factor
UGCG UDP-glucose ceramide glucosyltransferase
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2)
VWA8 von Willebrand factor A domain containing 8
WDR1 WD repeat domain 1
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZNF701 zinc finger protein 701

decreased expression

Symbol Name
ABHD8 abhydrolase domain containing 8
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
AKR1C3 aldo-keto reductase family 1, member C3
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
ANXA10 annexin A10
APOLD1 apolipoprotein L domain containing 1
ARAP3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
ARMC6 armadillo repeat containing 6
ASB13 ankyrin repeat and SOCS box containing 13
BAK1 BCL2-antagonist/killer 1
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCNJL cyclin J-like
CPEB1 cytoplasmic polyadenylation element binding protein 1
CSRNP3 cysteine-serine-rich nuclear protein 3
DHRS11 dehydrogenase/reductase (SDR family) member 11
DYSF dysferlin
ECM1 extracellular matrix protein 1
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5
ERMAP erythroblast membrane-associated protein (Scianna blood group)
ERMP1 endoplasmic reticulum metallopeptidase 1
ETNK2 ethanolamine kinase 2
F3 coagulation factor III (thromboplastin, tissue factor)
F8 coagulation factor VIII, procoagulant component
FHOD1 formin homology 2 domain containing 1
FIG4 FIG4 phosphoinositide 5-phosphatase
FZD3 frizzled class receptor 3
GRHL2 grainyhead-like 2 (Drosophila)
GTPBP2 GTP binding protein 2
HIRA histone cell cycle regulator
IFT46 intraflagellar transport 46
IFT54 intraflagellar transport 54
KDM5C lysine (K)-specific demethylase 5C
KIAA0513 KIAA0513
KIF13B kinesin family member 13B
KLC2 kinesin light chain 2
KLK5 kallikrein-related peptidase 5
LMNB1 lamin B1
LOC100272216 uncharacterized LOC100272216
LPAR3 lysophosphatidic acid receptor 3
MAN2B2 mannosidase, alpha, class 2B, member 2
MANBA mannosidase, beta A, lysosomal
MEIS1 Meis homeobox 1
MICALL2 MICAL-like 2
MNX1 motor neuron and pancreas homeobox 1
MXD3 MAX dimerization protein 3
NARFL nuclear prelamin A recognition factor-like
NDRG4 NDRG family member 4
NID2 nidogen 2 (osteonidogen)
NPDC1 neural proliferation, differentiation and control, 1
ORC1 origin recognition complex, subunit 1
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5
PAK6 p21 protein (Cdc42/Rac)-activated kinase 6
PALMD palmdelphin
PAQR4 progestin and adipoQ receptor family member IV
PARD6A par-6 family cell polarity regulator alpha
PLD2 phospholipase D2
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
PPP1R26 protein phosphatase 1, regulatory subunit 26
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PRR3 proline rich 3
PTGFR prostaglandin F receptor (FP)
PTTG3P pituitary tumor-transforming 3, pseudogene
RAB17 RAB17, member RAS oncogene family
RGS17 regulator of G-protein signaling 17
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
S100A9 S100 calcium binding protein A9
SALL2 spalt-like transcription factor 2
SCAMP5 secretory carrier membrane protein 5
SCPEP1 serine carboxypeptidase 1
SECTM1 secreted and transmembrane 1
SENP7 SUMO1/sentrin specific peptidase 7
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SMYD5 SMYD family member 5
SOX9 SRY (sex determining region Y)-box 9
SP140L SP140 nuclear body protein-like
SPAG4 sperm associated antigen 4
SPIDR scaffolding protein involved in DNA repair
STX1A syntaxin 1A (brain)
TAGLN3 transgelin 3
TBX19 T-box 19
TENM4 teneurin transmembrane protein 4
TGFB3 transforming growth factor, beta 3
TM7SF2 transmembrane 7 superfamily member 2
TMEM121 transmembrane protein 121
TMEM242 transmembrane protein 242
TNS2 tensin 2
TRIM9 tripartite motif containing 9
TXNL4B thioredoxin-like 4B
XK X-linked Kx blood group
XYLT2 xylosyltransferase II
ZC4H2 zinc finger, C4H2 domain containing
ZNF365 zinc finger protein 365
ZNF552 zinc finger protein 552
ZNF671 zinc finger protein 671
ZNF770 zinc finger protein 770
ZNHIT2 zinc finger, HIT-type containing 2