vincamine-3784 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the vincamine-3784 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2
ACSBG1 acyl-CoA synthetase bubblegum family member 1
ACTC1 actin, alpha, cardiac muscle 1
AFF1 AF4/FMR2 family, member 1
ALPK3 alpha-kinase 3
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide
BBC3 BCL2 binding component 3
BICD1 bicaudal D homolog 1 (Drosophila)
BIRC3 baculoviral IAP repeat containing 3
C1ORF68 chromosome 1 open reading frame 68
CACNG4 calcium channel, voltage-dependent, gamma subunit 4
CAPN9 calpain 9
CASP10 caspase 10, apoptosis-related cysteine peptidase
CDK18 cyclin-dependent kinase 18
CGA glycoprotein hormones, alpha polypeptide
CHAT choline O-acetyltransferase
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal)
CHRNE cholinergic receptor, nicotinic, epsilon (muscle)
CLDN1 claudin 1
CLTA clathrin, light chain A
COBL cordon-bleu WH2 repeat protein
CPB2 carboxypeptidase B2 (plasma)
CPN2 carboxypeptidase N, polypeptide 2
CRHR2 corticotropin releasing hormone receptor 2
CSHL1 chorionic somatomammotropin hormone-like 1
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
DIO2 deiodinase, iodothyronine, type II
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DOCK3 dedicator of cytokinesis 3
EGFL7 EGF-like-domain, multiple 7
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
ESR1 estrogen receptor 1
FGF4 fibroblast growth factor 4
FOSL2 FOS-like antigen 2
FZD1 frizzled class receptor 1
GAL3ST4 galactose-3-O-sulfotransferase 4
GFI1 growth factor independent 1 transcription repressor
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GRIP2 glutamate receptor interacting protein 2
HBE1 hemoglobin, epsilon 1
HCFC1 host cell factor C1
HEG1 heart development protein with EGF-like domains 1
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H)
IDS iduronate 2-sulfatase
IL32 interleukin 32
ING4 inhibitor of growth family, member 4
ITPK1 inositol-tetrakisphosphate 1-kinase
KCNMB1 potassium channel subfamily M regulatory beta subunit 1
KIAA1549L KIAA1549-like
KLHL25 kelch-like family member 25
KMT2A lysine (K)-specific methyltransferase 2A
LILRA1 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1
LOXL3 lysyl oxidase-like 3
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
LSP1 lymphocyte-specific protein 1
LUZP4 leucine zipper protein 4
MEFV Mediterranean fever
MSX2 msh homeobox 2
MUC3B mucin 3B, cell surface associated
MXD4 MAX dimerization protein 4
NMT2 N-myristoyltransferase 2
NUMA1 nuclear mitotic apparatus protein 1
OR2S2 olfactory receptor, family 2, subfamily S, member 2 (gene/pseudogene)
PARVA parvin, alpha
PDE10A phosphodiesterase 10A
PLIN2 perilipin 2
PRAF2 PRA1 domain family, member 2
PRB1 proline-rich protein BstNI subfamily 1
PROC protein C (inactivator of coagulation factors Va and VIIIa)
PRODH2 proline dehydrogenase (oxidase) 2
PTPN21 protein tyrosine phosphatase, non-receptor type 21
PVT1 Pvt1 oncogene (non-protein coding)
RAB6B RAB6B, member RAS oncogene family
RANBP1 RAN binding protein 1
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5
RASGRF1 Ras protein-specific guanine nucleotide-releasing factor 1
RGSL1 regulator of G-protein signaling like 1
SCN1B sodium channel, voltage gated, type I beta subunit
SLAMF7 SLAM family member 7
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
SLC28A1 solute carrier family 28 (concentrative nucleoside transporter), member 1
SLC48A1 solute carrier family 48 (heme transporter), member 1
SMO smoothened, frizzled class receptor
SOS2 son of sevenless homolog 2 (Drosophila)
SPTBN1 spectrin, beta, non-erythrocytic 1
ST8SIA4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
SWAP70 SWAP switching B-cell complex 70kDa subunit
TBCD tubulin folding cofactor D
TEX14 testis expressed 14
TLK1 tousled-like kinase 1
TRAFD1 TRAF-type zinc finger domain containing 1
TTC9 tetratricopeptide repeat domain 9
TUBA8 tubulin, alpha 8
UCP1 uncoupling protein 1 (mitochondrial, proton carrier)
UPK1B uroplakin 1B
ZC3H7B zinc finger CCCH-type containing 7B
ZNF3 zinc finger protein 3
ZNF506 zinc finger protein 506

decreased expression

Symbol Name
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ACSS3 acyl-CoA synthetase short-chain family member 3
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
ARMC4 armadillo repeat containing 4
BCHE butyrylcholinesterase
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BIRC7 baculoviral IAP repeat containing 7
C17ORF80 chromosome 17 open reading frame 80
CACNG1 calcium channel, voltage-dependent, gamma subunit 1
CBS cystathionine-beta-synthase
CCDC186 coiled-coil domain containing 186
CCDC71 coiled-coil domain containing 71
CCNJL cyclin J-like
CD70 CD70 molecule
CDH10 cadherin 10, type 2 (T2-cadherin)
CHM choroideremia (Rab escort protein 1)
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CSN3 casein kappa
CUZD1 CUB and zona pellucida-like domains 1
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
EGR2 early growth response 2
FAM120C family with sequence similarity 120C
FKBP10 FK506 binding protein 10, 65 kDa
FOXO4 forkhead box O4
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GDAP1 ganglioside induced differentiation associated protein 1
GEMIN8 gem (nuclear organelle) associated protein 8
GREB1L growth regulation by estrogen in breast cancer-like
HAAO 3-hydroxyanthranilate 3,4-dioxygenase
HHAT hedgehog acyltransferase
HLA-DMB major histocompatibility complex, class II, DM beta
IL2RG interleukin 2 receptor, gamma
KCNB1 potassium channel, voltage gated Shab related subfamily B, member 1
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KIAA0754 KIAA0754
KLF3 Kruppel-like factor 3 (basic)
KLHL28 kelch-like family member 28
LOC100127972 uncharacterized LOC100127972
LOC390998 ribosomal protein L10 pseudogene
LRRC2 leucine rich repeat containing 2
LRRC37A4P leucine rich repeat containing 37, member A4, pseudogene
LRRK1 leucine-rich repeat kinase 1
LTC4S leukotriene C4 synthase
MGC12488
MINOS1P1 mitochondrial inner membrane organizing system 1 pseudogene 1
MMP2 matrix metallopeptidase 2
MRPS18C mitochondrial ribosomal protein S18C
NACA2 nascent polypeptide-associated complex alpha subunit 2
NME5 NME/NM23 family member 5
NPM3 nucleophosmin/nucleoplasmin 3
NTF3 neurotrophin 3
NTNG1 netrin G1
OGDHL oxoglutarate dehydrogenase-like
OR1D2 olfactory receptor, family 1, subfamily D, member 2
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PAIP2B poly(A) binding protein interacting protein 2B
PCBP3 poly(rC) binding protein 3
PDE12 phosphodiesterase 12
PDPR pyruvate dehydrogenase phosphatase regulatory subunit
PLBD1 phospholipase B domain containing 1
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
POLL polymerase (DNA directed), lambda
PTGFR prostaglandin F receptor (FP)
R3HCC1L R3H domain and coiled-coil containing 1-like
REM1 RAS (RAD and GEM)-like GTP-binding 1
RGCC regulator of cell cycle
RUFY2 RUN and FYVE domain containing 2
SAYSD1 SAYSVFN motif domain containing 1
SCG2 secretogranin II
SCNN1G sodium channel, non voltage gated 1 gamma subunit
SENP7 SUMO1/sentrin specific peptidase 7
SERGEF secretion regulating guanine nucleotide exchange factor
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SP4 Sp4 transcription factor
STAG3L1 stromal antigen 3-like 1 (pseudogene)
STK16 serine/threonine kinase 16
SUSD4 sushi domain containing 4
SYTL2 synaptotagmin-like 2
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TAF5L TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
TBC1D8B TBC1 domain family, member 8B (with GRAM domain)
TPCN1 two pore segment channel 1
TRAC T cell receptor alpha constant
TRPV6 transient receptor potential cation channel, subfamily V, member 6
TSPAN32 tetraspanin 32
TUBA4B tubulin, alpha 4b
TUBG2 tubulin, gamma 2
ZNF137P zinc finger protein 137, pseudogene
ZNF358 zinc finger protein 358
ZNF528 zinc finger protein 528
ZNF639 zinc finger protein 639
ZNF76 zinc finger protein 76
ZNF767P zinc finger family member 767, pseudogene
ZSCAN2 zinc finger and SCAN domain containing 2