vincamine-3865 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the vincamine-3865 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
AHSG alpha-2-HS-glycoprotein
ALDOB aldolase B, fructose-bisphosphate
ALPPL2 alkaline phosphatase, placental-like 2
AMELX amelogenin, X-linked
APLP1 amyloid beta (A4) precursor-like protein 1
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
AVP arginine vasopressin
BAIAP3 BAI1-associated protein 3
BFSP2 beaded filament structural protein 2, phakinin
BTF3P11 basic transcription factor 3 pseudogene 11
C1ORF61 chromosome 1 open reading frame 61
C6ORF10 chromosome 6 open reading frame 10
CADM4 cell adhesion molecule 4
CASP1 caspase 1, apoptosis-related cysteine peptidase
CASP4 caspase 4, apoptosis-related cysteine peptidase
CCNK cyclin K
CD79A CD79a molecule, immunoglobulin-associated alpha
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
CNTN1 contactin 1
COL1A1 collagen, type I, alpha 1
CPA4 carboxypeptidase A4
CPNE7 copine VII
CRIP1 cysteine-rich protein 1 (intestinal)
CTIF CBP80/20-dependent translation initiation factor
CTNS cystinosin, lysosomal cystine transporter
CXCL6 chemokine (C-X-C motif) ligand 6
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
DUSP6 dual specificity phosphatase 6
EGR1 early growth response 1
EPS8L3 EPS8-like 3
ERC2-IT1 ERC2 intronic transcript 1
ERG v-ets avian erythroblastosis virus E26 oncogene homolog
EXOC6B exocyst complex component 6B
EXPH5 exophilin 5
F5 coagulation factor V (proaccelerin, labile factor)
FADS2 fatty acid desaturase 2
FAM49B family with sequence similarity 49, member B
FCN2 ficolin (collagen/fibrinogen domain containing lectin) 2
FN1 fibronectin 1
FRMD8 FERM domain containing 8
FSHB follicle stimulating hormone, beta polypeptide
GARNL3 GTPase activating Rap/RanGAP domain-like 3
GAST gastrin
GGTLC1 gamma-glutamyltransferase light chain 1
GLT8D2 glycosyltransferase 8 domain containing 2
GPR137 G protein-coupled receptor 137
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HLA-DOA major histocompatibility complex, class II, DO alpha
HPN hepsin
ICAM2 intercellular adhesion molecule 2
ICOSLG inducible T-cell co-stimulator ligand
IFT27 intraflagellar transport 27
IL21 interleukin 21
INHBA inhibin, beta A
IRAK3 interleukin-1 receptor-associated kinase 3
IRF4 interferon regulatory factor 4
IRS2 insulin receptor substrate 2
KLRD1 killer cell lectin-like receptor subfamily D, member 1
L3MBTL1 l(3)mbt-like 1 (Drosophila)
LEFTY1 left-right determination factor 1
LOC100131510 uncharacterized LOC100131510
MAPK10 mitogen-activated protein kinase 10
MAPRE3 microtubule-associated protein, RP/EB family, member 3
MST1 macrophage stimulating 1
MYCNOS MYCN opposite strand
NCDN neurochondrin
NEUROD4 neuronal differentiation 4
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NOL12 nucleolar protein 12
NOP16 NOP16 nucleolar protein
NR2E3 nuclear receptor subfamily 2, group E, member 3
ONECUT1 one cut homeobox 1
PMFBP1 polyamine modulated factor 1 binding protein 1
PQLC3 PQ loop repeat containing 3
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit
PROL1 proline rich, lacrimal 1
PRSS53 protease, serine, 53
PSG7 pregnancy specific beta-1-glycoprotein 7 (gene/pseudogene)
PTCRA pre T-cell antigen receptor alpha
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RBM48 RNA binding motif protein 48
RORC RAR-related orphan receptor C
RPS4Y1 ribosomal protein S4, Y-linked 1
SDS serine dehydratase
SERPINA7 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
SIRT4 sirtuin 4
SLC16A5 solute carrier family 16 (monocarboxylate transporter), member 5
SMG6 SMG6 nonsense mediated mRNA decay factor
SOX15 SRY (sex determining region Y)-box 15
SPTB spectrin, beta, erythrocytic
SYT13 synaptotagmin XIII
TMCC2 transmembrane and coiled-coil domain family 2
TMOD2 tropomodulin 2 (neuronal)
ZMIZ2 zinc finger, MIZ-type containing 2
ZNF117 zinc finger protein 117
ZNF136 zinc finger protein 136
ZNF37BP zinc finger protein 37B, pseudogene
ZNF702P zinc finger protein 702, pseudogene

decreased expression

Symbol Name
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ACTL8 actin-like 8
AFAP1 actin filament associated protein 1
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
ANKH ANKH inorganic pyrophosphate transport regulator
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle)
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ATP6V0A4 ATPase, H+ transporting, lysosomal V0 subunit a4
B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
BBC3 BCL2 binding component 3
C1ORF56 chromosome 1 open reading frame 56
CAMK1 calcium/calmodulin-dependent protein kinase I
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCDC25 coiled-coil domain containing 25
CCDC85C coiled-coil domain containing 85C
CD80 CD80 molecule
CD83 CD83 molecule
CDK6 cyclin-dependent kinase 6
CENPO centromere protein O
CEP85 centrosomal protein 85kDa
CGREF1 cell growth regulator with EF-hand domain 1
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DEPDC5 DEP domain containing 5
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
DNAH17 dynein, axonemal, heavy chain 17
DVL1 dishevelled segment polarity protein 1
ENO2 enolase 2 (gamma, neuronal)
ENO3 enolase 3 (beta, muscle)
ENOX1 ecto-NOX disulfide-thiol exchanger 1
FAM76A family with sequence similarity 76, member A
FBXO2 F-box protein 2
FBXW4P1 F-box and WD repeat domain containing 4 pseudogene 1
FFAR2 free fatty acid receptor 2
FKBP10 FK506 binding protein 10, 65 kDa
FXYD5 FXYD domain containing ion transport regulator 5
G6PD glucose-6-phosphate dehydrogenase
GALK1 galactokinase 1
GK3P glycerol kinase 3 pseudogene
GPT glutamic-pyruvate transaminase (alanine aminotransferase)
GTF2H4 general transcription factor IIH, polypeptide 4, 52kDa
GTF2I general transcription factor IIi
HDAC11 histone deacetylase 11
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HOOK1 hook microtubule-tethering protein 1
HOXA4 homeobox A4
HSD17B14 hydroxysteroid (17-beta) dehydrogenase 14
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
IPO8 importin 8
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
KCNK12 potassium channel, two pore domain subfamily K, member 12
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KREMEN2 kringle containing transmembrane protein 2
KRT15 keratin 15, type I
LOC729164 hCG1732469
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MAVS mitochondrial antiviral signaling protein
MVD mevalonate (diphospho) decarboxylase
NPM3 nucleophosmin/nucleoplasmin 3
PCDHGA8 protocadherin gamma subfamily A, 8
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RARRES3 retinoic acid receptor responder (tazarotene induced) 3
RCN1 reticulocalbin 1, EF-hand calcium binding domain
RNF146 ring finger protein 146
RNF25 ring finger protein 25
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
RPH3AL rabphilin 3A-like (without C2 domains)
RPL10L ribosomal protein L10-like
SCML2 sex comb on midleg-like 2 (Drosophila)
SDC3 syndecan 3
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SLC7A2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SPINK5 serine peptidase inhibitor, Kazal type 5
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STARD3 StAR-related lipid transfer (START) domain containing 3
SYT17 synaptotagmin XVII
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
TDRD1 tudor domain containing 1
TINF2 TERF1 (TRF1)-interacting nuclear factor 2
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TRDMT1 tRNA aspartic acid methyltransferase 1
TUBA3C tubulin, alpha 3c
TYRP1 tyrosinase-related protein 1
VIM vimentin
WDR4 WD repeat domain 4
WDR91 WD repeat domain 91
ZDHHC11 zinc finger, DHHC-type containing 11
ZMAT4 zinc finger, matrin-type 4
ZNF227 zinc finger protein 227
ZNF358 zinc finger protein 358
ZNF365 zinc finger protein 365
ZNF442 zinc finger protein 442