vincamine-3976 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the vincamine-3976 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AKR1C2 aldo-keto reductase family 1, member C2
AMT aminomethyltransferase
ANO1 anoctamin 1, calcium activated chloride channel
ARHGEF38 Rho guanine nucleotide exchange factor (GEF) 38
ART1 ADP-ribosyltransferase 1
ATG10 autophagy related 10
BHMT betaine--homocysteine S-methyltransferase
C11ORF16 chromosome 11 open reading frame 16
CACNA1G calcium channel, voltage-dependent, T type, alpha 1G subunit
CACNG1 calcium channel, voltage-dependent, gamma subunit 1
CAMK2B calcium/calmodulin-dependent protein kinase II beta
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CCRL2 chemokine (C-C motif) receptor-like 2
CD248 CD248 molecule, endosialin
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CLTA clathrin, light chain A
COL6A3 collagen, type VI, alpha 3
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1
CYP2B7P cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene
DCT dopachrome tautomerase
DNM2 dynamin 2
EGR4 early growth response 4
ERICH1 glutamate-rich 1
EXPH5 exophilin 5
F13B coagulation factor XIII, B polypeptide
F2RL2 coagulation factor II (thrombin) receptor-like 2
FLJ11292
FUT7 fucosyltransferase 7 (alpha (1,3) fucosyltransferase)
FZD9 frizzled class receptor 9
GAP43 growth associated protein 43
GK2 glycerol kinase 2
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
GPR183 G protein-coupled receptor 183
HECW1 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
HERC2P3 hect domain and RLD 2 pseudogene 3
HIF3A hypoxia inducible factor 3, alpha subunit
HRH4 histamine receptor H4
HSPB6 heat shock protein, alpha-crystallin-related, B6
IFNA10 interferon, alpha 10
IGFBP7 insulin-like growth factor binding protein 7
JAM2 junctional adhesion molecule 2
KCNJ8 potassium channel, inwardly rectifying subfamily J, member 8
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KLK8 kallikrein-related peptidase 8
KRT23 keratin 23, type I
LAMB4 laminin, beta 4
MBD2 methyl-CpG binding domain protein 2
MNDA myeloid cell nuclear differentiation antigen
MPZ myelin protein zero
MST1R macrophage stimulating 1 receptor
MTL5 metallothionein-like 5, testis-specific (tesmin)
MYBPC3 myosin binding protein C, cardiac
NAG18 NAG18 mRNA
NCR3 natural cytotoxicity triggering receptor 3
NTF3 neurotrophin 3
NUDT11 nudix (nucleoside diphosphate linked moiety X)-type motif 11
NUP88 nucleoporin 88kDa
OLIG2 oligodendrocyte lineage transcription factor 2
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PCDHB11 protocadherin beta 11
PCDHGA10 protocadherin gamma subfamily A, 10
PHLDB1 pleckstrin homology-like domain, family B, member 1
PKNOX2 PBX/knotted 1 homeobox 2
PLA2G5 phospholipase A2, group V
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
POLL polymerase (DNA directed), lambda
POU5F1B POU class 5 homeobox 1B
PPARD peroxisome proliferator-activated receptor delta
PPP1R1A protein phosphatase 1, regulatory (inhibitor) subunit 1A
PPP2R5B protein phosphatase 2, regulatory subunit B', beta
PRKY protein kinase, Y-linked, pseudogene
RHAG Rh-associated glycoprotein
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)
ROBO4 roundabout, axon guidance receptor, homolog 4 (Drosophila)
RPL35A ribosomal protein L35a
RPL7 ribosomal protein L7
RUNDC3A RUN domain containing 3A
SBNO2 strawberry notch homolog 2 (Drosophila)
SCN11A sodium channel, voltage gated, type XI alpha subunit
SFTPB surfactant protein B
SIRPB1 signal-regulatory protein beta 1
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
SORBS2 sorbin and SH3 domain containing 2
SRD5A2 steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)
ST8SIA3 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
TAS2R4 taste receptor, type 2, member 4
TBC1D2 TBC1 domain family, member 2
TESPA1 thymocyte expressed, positive selection associated 1
THSD4 thrombospondin, type I, domain containing 4
TJAP1 tight junction associated protein 1 (peripheral)
TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
TNNT3 troponin T type 3 (skeletal, fast)
TRAPPC9 trafficking protein particle complex 9
TRIM10 tripartite motif containing 10
UBA6 ubiquitin-like modifier activating enzyme 6
UBXN1 UBX domain protein 1
VCAN versican
ZNF235 zinc finger protein 235
ZNF280A zinc finger protein 280A
ZNF280B zinc finger protein 280B

decreased expression

Symbol Name
A1CF APOBEC1 complementation factor
ACSBG2 acyl-CoA synthetase bubblegum family member 2
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13
AHNAK2 AHNAK nucleoprotein 2
AIRE autoimmune regulator
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle)
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
ARC activity-regulated cytoskeleton-associated protein
ASIC1 acid sensing (proton gated) ion channel 1
BET1L Bet1 golgi vesicular membrane trafficking protein-like
BMP4 bone morphogenetic protein 4
BRINP2 bone morphogenetic protein/retinoic acid inducible neural-specific 2
C8ORF44 chromosome 8 open reading frame 44
CDK18 cyclin-dependent kinase 18
CDK3 cyclin-dependent kinase 3
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CNTFR ciliary neurotrophic factor receptor
CNTN1 contactin 1
CPEB3 cytoplasmic polyadenylation element binding protein 3
CRTC1 CREB regulated transcription coactivator 1
CST6 cystatin E/M
CTRL chymotrypsin-like
DBF4B DBF4 zinc finger B
DCBLD2 discoidin, CUB and LCCL domain containing 2
DPY19L1P1 DPY19L1 pseudogene 1
DYM dymeclin
EFNA3 ephrin-A3
EFNB3 ephrin-B3
ELAVL2 ELAV like neuron-specific RNA binding protein 2
EMP3 epithelial membrane protein 3
ENO3 enolase 3 (beta, muscle)
FBXW4P1 F-box and WD repeat domain containing 4 pseudogene 1
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FRAS1 Fraser extracellular matrix complex subunit 1
FRK fyn-related Src family tyrosine kinase
FRMD1 FERM domain containing 1
FSTL1 follistatin-like 1
GCGR glucagon receptor
GFPT2 glutamine-fructose-6-phosphate transaminase 2
GPR1 G protein-coupled receptor 1
GPR143 G protein-coupled receptor 143
GPR39 G protein-coupled receptor 39
HAAO 3-hydroxyanthranilate 3,4-dioxygenase
HDAC11 histone deacetylase 11
IL2RG interleukin 2 receptor, gamma
ITM2C integral membrane protein 2C
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3
LOC642236 FSHD region gene 1 pseudogene
LRP3 low density lipoprotein receptor-related protein 3
LZTS3 leucine zipper, putative tumor suppressor family member 3
MALL mal, T-cell differentiation protein-like
MAST3 microtubule associated serine/threonine kinase 3
MCTP1 multiple C2 domains, transmembrane 1
MYL12A myosin, light chain 12A, regulatory, non-sarcomeric
MYO1F myosin IF
NPY neuropeptide Y
NPY4R neuropeptide Y receptor Y4
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2
PCDH17 protocadherin 17
PDE12 phosphodiesterase 12
PMCH pro-melanin-concentrating hormone
PRPH peripherin
PVRL3 poliovirus receptor-related 3
RAB40AL RAB40A, member RAS oncogene family-like
ROBO3 roundabout, axon guidance receptor, homolog 3 (Drosophila)
SGCE sarcoglycan, epsilon
SLC10A1 solute carrier family 10 (sodium/bile acid cotransporter), member 1
SLC12A8 solute carrier family 12, member 8
SLC2A9 solute carrier family 2 (facilitated glucose transporter), member 9
SLC52A1 solute carrier family 52 (riboflavin transporter), member 1
SLC9A5 solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5
SLCO1C1 solute carrier organic anion transporter family, member 1C1
SOAT2 sterol O-acyltransferase 2
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
SPTBN2 spectrin, beta, non-erythrocytic 2
SYT17 synaptotagmin XVII
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TEX40 testis expressed 40
TLR5 toll-like receptor 5
TMEM158 transmembrane protein 158 (gene/pseudogene)
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
TOR4A torsin family 4, member A
TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
UPP1 uridine phosphorylase 1
VAV1 vav 1 guanine nucleotide exchange factor
WDR33 WD repeat domain 33
WDR78 WD repeat domain 78
WNT10B wingless-type MMTV integration site family, member 10B
ZNF532 zinc finger protein 532
ZNF551 zinc finger protein 551
ZNF682 zinc finger protein 682
ZNF747 zinc finger protein 747