vincamine-4341 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the vincamine-4341 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACTN2 actinin, alpha 2
ARTN artemin
ASPN asporin
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2
BAIAP3 BAI1-associated protein 3
BATF basic leucine zipper transcription factor, ATF-like
BIRC3 baculoviral IAP repeat containing 3
BRE brain and reproductive organ-expressed (TNFRSF1A modulator)
BRINP2 bone morphogenetic protein/retinoic acid inducible neural-specific 2
CASP2 caspase 2, apoptosis-related cysteine peptidase
CCNK cyclin K
CD6 CD6 molecule
CLTB clathrin, light chain B
CR1 complement component (3b/4b) receptor 1 (Knops blood group)
CRISP2 cysteine-rich secretory protein 2
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
CTSZ cathepsin Z
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL8 chemokine (C-X-C motif) ligand 8
DENND3 DENN/MADD domain containing 3
DMXL2 Dmx-like 2
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12
DSCAM Down syndrome cell adhesion molecule
EDN1 endothelin 1
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
ELAC2 elaC ribonuclease Z 2
ENC1 ectodermal-neural cortex 1 (with BTB domain)
ERN2 endoplasmic reticulum to nucleus signaling 2
EXOSC2 exosome component 2
EZR ezrin
FARP2 FERM, RhoGEF and pleckstrin domain protein 2
FOXN2 forkhead box N2
GADD45B growth arrest and DNA-damage-inducible, beta
GGA1 golgi-associated, gamma adaptin ear containing, ARF binding protein 1
GPR135 G protein-coupled receptor 135
H2AFX H2A histone family, member X
HBS1L HBS1-like translational GTPase
HIST1H1E histone cluster 1, H1e
HPX hemopexin
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
HTR1F 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled
IDS iduronate 2-sulfatase
IL7R interleukin 7 receptor
INHBA inhibin, beta A
KIR2DS1 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1
KIRREL kin of IRRE like (Drosophila)
KRT34 keratin 34, type I
LIF leukemia inhibitory factor
MAPK8 mitogen-activated protein kinase 8
MCF2L MCF.2 cell line derived transforming sequence-like
MCM3AP minichromosome maintenance complex component 3 associated protein
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MOBP myelin-associated oligodendrocyte basic protein
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NFX1 nuclear transcription factor, X-box binding 1
NOP14-AS1 NOP14 antisense RNA 1
OPRL1 opiate receptor-like 1
PASK PAS domain containing serine/threonine kinase
PAWR PRKC, apoptosis, WT1, regulator
PEX16 peroxisomal biogenesis factor 16
PKNOX1 PBX/knotted 1 homeobox 1
PMS2P3 postmeiotic segregation increased 2 pseudogene 3
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta
PSG11 pregnancy specific beta-1-glycoprotein 11
PTGER1 prostaglandin E receptor 1 (subtype EP1), 42kDa
PVT1 Pvt1 oncogene (non-protein coding)
PYHIN1 pyrin and HIN domain family, member 1
RAB2A RAB2A, member RAS oncogene family
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2
RARB retinoic acid receptor, beta
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RND1 Rho family GTPase 1
RPL10L ribosomal protein L10-like
RPLP2 ribosomal protein, large, P2
SAMD4A sterile alpha motif domain containing 4A
SARM1 sterile alpha and TIR motif containing 1
SFTPB surfactant protein B
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
SLC25A30 solute carrier family 25, member 30
SNAPC4 small nuclear RNA activating complex, polypeptide 4, 190kDa
SP4 Sp4 transcription factor
TBC1D30 TBC1 domain family, member 30
TGFB2 transforming growth factor, beta 2
TGM4 transglutaminase 4
TIMM8A translocase of inner mitochondrial membrane 8 homolog A (yeast)
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNK2 tyrosine kinase, non-receptor, 2
TP63 tumor protein p63
TPP1 tripeptidyl peptidase I
TUB tubby bipartite transcription factor
TXN thioredoxin
UBE2I ubiquitin-conjugating enzyme E2I
UGCG UDP-glucose ceramide glucosyltransferase
VSNL1 visinin-like 1
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6
ZBTB17 zinc finger and BTB domain containing 17
ZNF234 zinc finger protein 234
ZNF639 zinc finger protein 639

decreased expression

Symbol Name
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ABHD17B abhydrolase domain containing 17B
ABHD8 abhydrolase domain containing 8
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
AFF4 AF4/FMR2 family, member 4
ALOX12P2 arachidonate 12-lipoxygenase pseudogene 2
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
ARHGEF10L Rho guanine nucleotide exchange factor (GEF) 10-like
ARHGEF38 Rho guanine nucleotide exchange factor (GEF) 38
ARID3A AT rich interactive domain 3A (BRIGHT-like)
ASIC3 acid sensing (proton gated) ion channel 3
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
BEX4 brain expressed, X-linked 4
BPHL biphenyl hydrolase-like (serine hydrolase)
BRIP1 BRCA1 interacting protein C-terminal helicase 1
C1ORF54 chromosome 1 open reading frame 54
C5 complement component 5
CCNG2 cyclin G2
CD101 CD101 molecule
CD68 CD68 molecule
CDK6 cyclin-dependent kinase 6
CEMIP cell migration inducing protein, hyaluronan binding
CPNE7 copine VII
CXCL3 chemokine (C-X-C motif) ligand 3
DBR1 debranching RNA lariats 1
DEAF1 DEAF1 transcription factor
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DOK5 docking protein 5
DTX2 deltex 2, E3 ubiquitin ligase
EFNB1 ephrin-B1
EGF epidermal growth factor
EXOC5 exocyst complex component 5
FAM105A family with sequence similarity 105, member A
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12
GK3P glycerol kinase 3 pseudogene
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GNA14 guanine nucleotide binding protein (G protein), alpha 14
GTF2I general transcription factor IIi
H1F0 H1 histone family, member 0
IFI44L interferon-induced protein 44-like
IFT81 intraflagellar transport 81
IPO8 importin 8
KDM5C lysine (K)-specific demethylase 5C
KIAA0319L KIAA0319-like
KRT15 keratin 15, type I
LIG4 ligase IV, DNA, ATP-dependent
LINC00115 long intergenic non-protein coding RNA 115
LMAN1 lectin, mannose-binding, 1
LPAR3 lysophosphatidic acid receptor 3
LPAR6 lysophosphatidic acid receptor 6
LRRC61 leucine rich repeat containing 61
LRRK1 leucine-rich repeat kinase 1
LYPD3 LY6/PLAUR domain containing 3
MANSC1 MANSC domain containing 1
MBTPS2 membrane-bound transcription factor peptidase, site 2
MMP9 matrix metallopeptidase 9
MUC3B mucin 3B, cell surface associated
NDP Norrie disease (pseudoglioma)
NID2 nidogen 2 (osteonidogen)
NUS1P3 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) pseudogene 3
OARD1 O-acyl-ADP-ribose deacylase 1
OSMR oncostatin M receptor
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PALMD palmdelphin
PECR peroxisomal trans-2-enoyl-CoA reductase
PIN1P1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 pseudogene 1
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
POLL polymerase (DNA directed), lambda
POM121L2 POM121 transmembrane nucleoporin-like 2
PSAT1 phosphoserine aminotransferase 1
PTGFR prostaglandin F receptor (FP)
PTPRU protein tyrosine phosphatase, receptor type, U
RAB23 RAB23, member RAS oncogene family
RHBDD3 rhomboid domain containing 3
RNF146 ring finger protein 146
S1PR1 sphingosine-1-phosphate receptor 1
SEPP1 selenoprotein P, plasma, 1
SGPP1 sphingosine-1-phosphate phosphatase 1
SH3BGRL SH3 domain binding glutamate-rich protein like
SLC6A20 solute carrier family 6 (proline IMINO transporter), member 20
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SLITRK5 SLIT and NTRK-like family, member 5
SNRPN small nuclear ribonucleoprotein polypeptide N
SPRY2 sprouty homolog 2 (Drosophila)
SPTLC3 serine palmitoyltransferase, long chain base subunit 3
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
TAGLN3 transgelin 3
TGIF1 TGFB-induced factor homeobox 1
TINAGL1 tubulointerstitial nephritis antigen-like 1
TLN1 talin 1
TMEM230 transmembrane protein 230
TXK TXK tyrosine kinase
UGT8 UDP glycosyltransferase 8
WDR76 WD repeat domain 76
WNT10B wingless-type MMTV integration site family, member 10B
ZBTB22 zinc finger and BTB domain containing 22
ZBTB6 zinc finger and BTB domain containing 6
ZFHX3 zinc finger homeobox 3