| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | vincristine perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the vincristine_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | 0.278995 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.263802 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.248341 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.185592 |
| PCDH7 | protocadherin 7 | 0.141249 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.133559 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.132606 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.128401 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.118534 |
| DST | dystonin | 0.117148 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.113339 |
| AREG | amphiregulin | 0.10677 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.100917 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.100262 |
| LDHA | lactate dehydrogenase A | 0.0999204 |
| DPYD | dihydropyrimidine dehydrogenase | 0.096406 |
| RASAL2 | RAS protein activator like 2 | 0.0955187 |
| ANXA1 | annexin A1 | 0.0954259 |
| CLDN1 | claudin 1 | 0.095342 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0873628 |
| MMP12 | matrix metallopeptidase 12 | 0.0873492 |
| RPL3 | ribosomal protein L3 | 0.0828704 |
| RTN4 | reticulon 4 | 0.0792421 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0724872 |
| TPM3 | tropomyosin 3 | 0.0690202 |
| YBX3 | Y box binding protein 3 | 0.0675507 |
| MYL12B | myosin, light chain 12B, regulatory | 0.0672558 |
| MARCHF4 | membrane associated ring-CH-type finger 4 | 0.0658838 |
| GJA1 | gap junction protein, alpha 1, 43kDa | 0.0650149 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.062953 |
| TXNRD1 | thioredoxin reductase 1 | 0.062943 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0596218 |
| JMJD1C | jumonji domain containing 1C | 0.058683 |
| MKI67 | marker of proliferation Ki-67 | 0.058475 |
| CCN2 | cellular communication network factor 2 | 0.0582804 |
| PDGFC | platelet derived growth factor C | 0.0546454 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | 0.0545766 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0538112 |
| HMGA2 | high mobility group AT-hook 2 | 0.0525855 |
| DTNA | dystrobrevin, alpha | 0.0512013 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0510813 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0501437 |
| EZR | ezrin | 0.0495702 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | 0.0486261 |
| OLR1 | oxidized low density lipoprotein (lectin-like) receptor 1 | 0.0485461 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0475392 |
| IPO7 | importin 7 | 0.0474299 |
| PLK2 | polo-like kinase 2 | 0.0473869 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0454495 |
| ASPH | aspartate beta-hydroxylase | 0.0450564 |
| CUBN | cubilin (intrinsic factor-cobalamin receptor) | 0.0444887 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.043891 |
| ACTG1 | actin gamma 1 | 0.0428651 |
| TPM4 | tropomyosin 4 | 0.0428354 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0425433 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0424943 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0422424 |
| POTEF | POTE ankyrin domain family, member F | 0.0412508 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.0403148 |
| RPS4X | ribosomal protein S4, X-linked | 0.0393934 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0388393 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0383567 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0378815 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0376534 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.037547 |
| EGFR | epidermal growth factor receptor | 0.0362912 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.036147 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | 0.0347951 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0345892 |
| DLC1 | DLC1 Rho GTPase activating protein | 0.0340672 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0332098 |
| CANX | calnexin | 0.0328008 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | 0.0326594 |
| ENO1 | enolase 1, (alpha) | 0.0324007 |
| KRR1 | KRR1, small subunit (SSU) processome component, homolog (yeast) | 0.0321337 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0321068 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0319247 |
| NABP1 | nucleic acid binding protein 1 | 0.0315537 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0314149 |
| TCP1 | t-complex 1 | 0.0309589 |
| PRDX1 | peroxiredoxin 1 | 0.0308013 |
| CPNE1 | copine I | 0.0305492 |
| PRR16 | proline rich 16 | 0.03052 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0301261 |
| UBC | ubiquitin C | 0.0299201 |
| CLTC | clathrin, heavy chain (Hc) | 0.0296608 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0294053 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.029212 |
| GCG | glucagon | 0.0284609 |
| TGM2 | transglutaminase 2 | 0.0282648 |
| NAV3 | neuron navigator 3 | 0.0280861 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.028057 |
| RAB10 | RAB10, member RAS oncogene family | 0.0280184 |
| VMP1 | vacuole membrane protein 1 | 0.0275965 |
| TENM3 | teneurin transmembrane protein 3 | 0.0274486 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0273938 |
| UHMK1 | U2AF homology motif (UHM) kinase 1 | 0.0273756 |
| PRKCE | protein kinase C, epsilon | 0.0271257 |
| NEGR1 | neuronal growth regulator 1 | 0.0270239 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0269718 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0543493 |
| RPS29 | ribosomal protein S29 | -0.0465854 |
| PTMA | prothymosin, alpha | -0.0394417 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0389728 |
| TUBA1B | tubulin, alpha 1b | -0.0361781 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0337689 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0328674 |
| RPL37A | ribosomal protein L37a | -0.0319391 |
| FTL | ferritin, light polypeptide | -0.0316652 |
| RPL38 | ribosomal protein L38 | -0.0302287 |
| TMSB10 | thymosin beta 10 | -0.0301645 |
| RPL31 | ribosomal protein L31 | -0.0295723 |
| TUBB | tubulin, beta class I | -0.0295006 |
| H1-0 | H1.0 linker histone | -0.0289928 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0288067 |
| RPS19 | ribosomal protein S19 | -0.0261692 |
| RPL35A | ribosomal protein L35a | -0.0261478 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0252068 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | -0.0240442 |
| RPS23 | ribosomal protein S23 | -0.0237514 |
| NLGN1 | neuroligin 1 | -0.0227069 |
| CDH12 | cadherin 12, type 2 (N-cadherin 2) | -0.0226353 |
| RPLP1 | ribosomal protein, large, P1 | -0.0222471 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0218428 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0215474 |
| EHBP1 | EH domain binding protein 1 | -0.021481 |
| RPS27A | ribosomal protein S27a | -0.0213045 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0208139 |
| NEMF | nuclear export mediator factor | -0.0207443 |
| ARHGAP12 | Rho GTPase activating protein 12 | -0.0205455 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0205275 |
| ZNF804A | zinc finger protein 804A | -0.0203437 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0200398 |
| DDB2 | damage-specific DNA binding protein 2, 48kDa | -0.0199132 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | -0.0198636 |
| RPL11 | ribosomal protein L11 | -0.0195384 |
| ETV6 | ets variant 6 | -0.0193843 |
| USP34 | ubiquitin specific peptidase 34 | -0.0193824 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0191725 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0190609 |
| SMYD3 | SET and MYND domain containing 3 | -0.0189841 |
| PEG10 | paternally expressed 10 | -0.0189364 |
| RPS21 | ribosomal protein S21 | -0.0187365 |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 | -0.0186143 |
| RPS13 | ribosomal protein S13 | -0.0184479 |
| RAD51B | RAD51 paralog B | -0.017947 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0176969 |
| RPL36 | ribosomal protein L36 | -0.0174877 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0173369 |
| KLHL24 | kelch-like family member 24 | -0.0172708 |
| HMGA1 | high mobility group AT-hook 1 | -0.0171788 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | -0.0170136 |
| CCDC88A | coiled-coil domain containing 88A | -0.0169452 |
| ZNF292 | zinc finger protein 292 | -0.0168761 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0164899 |
| CDK6 | cyclin-dependent kinase 6 | -0.0163096 |
| SYT1 | synaptotagmin I | -0.0162459 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0161915 |
| ABI2 | abl-interactor 2 | -0.0161672 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | -0.0161364 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0160269 |
| RPS6 | ribosomal protein S6 | -0.0158433 |
| RPS24 | ribosomal protein S24 | -0.0158228 |
| HMGB1 | high mobility group box 1 | -0.0157237 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0157019 |
| CXADR | coxsackie virus and adenovirus receptor | -0.0155045 |
| RBM39 | RNA binding motif protein 39 | -0.0154888 |
| PDE8A | phosphodiesterase 8A | -0.0153246 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.0151085 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | -0.0150794 |
| TMEM131 | transmembrane protein 131 | -0.0150319 |
| NFIA | nuclear factor I/A | -0.014952 |
| PHF21A | PHD finger protein 21A | -0.014948 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0147154 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0146353 |
| TUBA1A | tubulin, alpha 1a | -0.0145728 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0143957 |
| RPL26 | ribosomal protein L26 | -0.0143364 |
| TUSC3 | tumor suppressor candidate 3 | -0.0142323 |
| HLA-B | major histocompatibility complex, class I, B | -0.0140307 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0140289 |
| MECOM | MDS1 and EVI1 complex locus | -0.0138915 |
| TM7SF3 | transmembrane 7 superfamily member 3 | -0.0138912 |
| B2M | beta-2-microglobulin | -0.0138235 |
| RFX7 | regulatory factor X, 7 | -0.0137722 |
| CHD9 | chromodomain helicase DNA binding protein 9 | -0.0136899 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0136024 |
| RPS16 | ribosomal protein S16 | -0.0135518 |
| XPO7 | exportin 7 | -0.013519 |
| TMEM108 | transmembrane protein 108 | -0.0134065 |
| RPL12 | ribosomal protein L12 | -0.0133854 |
| NBDY | negative regulator of P-body association | -0.0133225 |
| TNRC6B | trinucleotide repeat containing 6B | -0.0131376 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0131049 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0129866 |
| RPL9 | ribosomal protein L9 | -0.0129661 |
| FAM133B | family with sequence similarity 133, member B | -0.0128429 |
| RPL36A | ribosomal protein L36a | -0.0127861 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0127124 |
| PCF11 | PCF11 cleavage and polyadenylation factor subunit | -0.01268 |
