| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | vincristine perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the vincristine_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | 0.105811 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0914286 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0910443 |
| ATXN1 | ataxin 1 | 0.0836036 |
| TPM4 | tropomyosin 4 | 0.0778262 |
| LDHA | lactate dehydrogenase A | 0.0690363 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0685992 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0651628 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0648999 |
| RPL3 | ribosomal protein L3 | 0.0642087 |
| ASPH | aspartate beta-hydroxylase | 0.0610876 |
| MYO5B | myosin VB | 0.054033 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0530468 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0499261 |
| AHNAK | AHNAK nucleoprotein | 0.049871 |
| ANXA2 | annexin A2 | 0.0448403 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.044531 |
| SVIL | supervillin | 0.0440574 |
| FLNB | filamin B, beta | 0.0432007 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0422455 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.041702 |
| FTL | ferritin, light polypeptide | 0.0397273 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.039176 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0380024 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0379078 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.037696 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0373397 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0356388 |
| TES | testin LIM domain protein | 0.0354208 |
| VEGFA | vascular endothelial growth factor A | 0.0349908 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0349575 |
| DSPP | dentin sialophosphoprotein | 0.0344116 |
| FLNA | filamin A, alpha | 0.0343246 |
| ACTG1 | actin gamma 1 | 0.0335034 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0330653 |
| JMJD1C | jumonji domain containing 1C | 0.033035 |
| NDRG1 | N-myc downstream regulated 1 | 0.0326849 |
| RPL13A | ribosomal protein L13a | 0.0321058 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0318854 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.031674 |
| TMSB4X | thymosin beta 4, X-linked | 0.0302459 |
| ANXA1 | annexin A1 | 0.030011 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0299529 |
| HSPA8 | heat shock 70kDa protein 8 | 0.029852 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0292804 |
| RPL18A | ribosomal protein L18a | 0.0292241 |
| KLF6 | Kruppel-like factor 6 | 0.0290151 |
| S100A6 | S100 calcium binding protein A6 | 0.0289532 |
| SOX4 | SRY (sex determining region Y)-box 4 | 0.0285941 |
| CANX | calnexin | 0.0285237 |
| RPS4X | ribosomal protein S4, X-linked | 0.0284935 |
| PLEC | plectin | 0.0280823 |
| NEBL | nebulette | 0.0280269 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0277497 |
| PARD3 | par-3 family cell polarity regulator | 0.0273633 |
| SMYD3 | SET and MYND domain containing 3 | 0.0270231 |
| CALR | calreticulin | 0.0270067 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0262847 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0261131 |
| TXNIP | thioredoxin interacting protein | 0.0254941 |
| USP53 | ubiquitin specific peptidase 53 | 0.0250922 |
| TJP1 | tight junction protein 1 | 0.0249412 |
| S100A10 | S100 calcium binding protein A10 | 0.02482 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0246085 |
| TRPS1 | trichorhinophalangeal syndrome I | 0.0240893 |
| APP | amyloid beta (A4) precursor protein | 0.0237127 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0235024 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0234816 |
| RND3 | Rho family GTPase 3 | 0.0230318 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0227768 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0226492 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0225973 |
| PALLD | palladin, cytoskeletal associated protein | 0.0223342 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0222194 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.021942 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0217281 |
| LYST | lysosomal trafficking regulator | 0.0215036 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.0211327 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0211178 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0207196 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0206323 |
| MANF | mesencephalic astrocyte-derived neurotrophic factor | 0.020548 |
| DAAM1 | dishevelled associated activator of morphogenesis 1 | 0.0203119 |
| TMCO3 | transmembrane and coiled-coil domains 3 | 0.020266 |
| MYOF | myoferlin | 0.0202548 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0201471 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0200786 |
| SH3RF2 | SH3 domain containing ring finger 2 | 0.0198558 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0196677 |
| PTEN | phosphatase and tensin homolog | 0.0196082 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.0195375 |
| TPM3 | tropomyosin 3 | 0.0194563 |
| DST | dystonin | 0.0194022 |
| CLOCK | clock circadian regulator | 0.019388 |
| MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | 0.0191186 |
| ARFGEF3 | ARFGEF family member 3 | 0.0190443 |
| RTN4 | reticulon 4 | 0.0189497 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0189048 |
| DUSP4 | dual specificity phosphatase 4 | 0.0188862 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0187853 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.316031 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.178641 |
| NPSR1 | neuropeptide S receptor 1 | -0.108909 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.104419 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.103166 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0800806 |
| RPL35A | ribosomal protein L35a | -0.0681038 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.066193 |
| GPHN | gephyrin | -0.0657476 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0617881 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.054679 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0516758 |
| RPS24 | ribosomal protein S24 | -0.0515696 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.048917 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0460691 |
| TNS4 | tensin 4 | -0.0419787 |
| NFIA | nuclear factor I/A | -0.0388575 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0379627 |
| TUBA1B | tubulin, alpha 1b | -0.036714 |
| TRIM2 | tripartite motif containing 2 | -0.0363006 |
| H1-0 | H1.0 linker histone | -0.0354244 |
| FAT1 | FAT atypical cadherin 1 | -0.0348029 |
| IER3 | immediate early response 3 | -0.0346087 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | -0.0345537 |
| TUBB | tubulin, beta class I | -0.0341963 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | -0.0324845 |
| FERMT1 | fermitin family member 1 | -0.0318331 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0315502 |
| RPL37A | ribosomal protein L37a | -0.0308403 |
| PKP2 | plakophilin 2 | -0.0306895 |
| GREB1L | growth regulation by estrogen in breast cancer-like | -0.0294878 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0288387 |
| EPCAM | epithelial cell adhesion molecule | -0.0287503 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0275339 |
| MLEC | malectin | -0.0272253 |
| KLK10 | kallikrein-related peptidase 10 | -0.0259608 |
| RPL23 | ribosomal protein L23 | -0.025833 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | -0.0255855 |
| TFF1 | trefoil factor 1 | -0.0254374 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0253085 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0249694 |
| RPS27A | ribosomal protein S27a | -0.024664 |
| RPL9 | ribosomal protein L9 | -0.0241297 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0240648 |
| MYO1E | myosin IE | -0.0240194 |
| CCND1 | cyclin D1 | -0.0233938 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0233488 |
| HMGA1 | high mobility group AT-hook 1 | -0.0233395 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0232312 |
| FHIT | fragile histidine triad | -0.0231831 |
| PIGR | polymeric immunoglobulin receptor | -0.023137 |
| RAD51B | RAD51 paralog B | -0.0227749 |
| TFF3 | trefoil factor 3 (intestinal) | -0.0224156 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0223247 |
| SAMD5 | sterile alpha motif domain containing 5 | -0.021977 |
| PPP2R5C | protein phosphatase 2, regulatory subunit B', gamma | -0.0217165 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0216841 |
| PRSS3 | protease, serine, 3 | -0.021553 |
| KIF5B | kinesin family member 5B | -0.0213136 |
| HDAC2 | histone deacetylase 2 | -0.0211958 |
| TUBA1C | tubulin, alpha 1c | -0.0211134 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0210915 |
| RPLP0 | ribosomal protein, large, P0 | -0.0209587 |
| MSI2 | musashi RNA-binding protein 2 | -0.0208373 |
| TANC1 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 | -0.0208124 |
| KRT8 | keratin 8, type II | -0.0208013 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0207549 |
| RPS6 | ribosomal protein S6 | -0.0204509 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0204328 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.0203795 |
| CDK6 | cyclin-dependent kinase 6 | -0.0202558 |
| EGR1 | early growth response 1 | -0.019974 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0199132 |
| RAB10 | RAB10, member RAS oncogene family | -0.019382 |
| RPS8 | ribosomal protein S8 | -0.0193805 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.019341 |
| SERINC5 | serine incorporator 5 | -0.0189709 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | -0.0189064 |
| LAMA4 | laminin, alpha 4 | -0.0184928 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | -0.0184759 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0182957 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | -0.0182751 |
| RHPN2 | rhophilin, Rho GTPase binding protein 2 | -0.0181924 |
| VCL | vinculin | -0.0181853 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0181589 |
| RPS13 | ribosomal protein S13 | -0.0180251 |
| RPS23 | ribosomal protein S23 | -0.0178866 |
| CPT1A | carnitine palmitoyltransferase 1A (liver) | -0.0178847 |
| RPL11 | ribosomal protein L11 | -0.0177822 |
| S100A9 | S100 calcium binding protein A9 | -0.0177707 |
| RPL36A | ribosomal protein L36a | -0.0177638 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0176926 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0175368 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.017379 |
| GPA33 | glycoprotein A33 (transmembrane) | -0.0173144 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.0172874 |
| RPL31 | ribosomal protein L31 | -0.0172699 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0172483 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | -0.017126 |
| CACNB2 | calcium channel, voltage-dependent, beta 2 subunit | -0.0168684 |
