| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | vincristine perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the vincristine_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.254689 |
| KRT18 | keratin 18, type I | 0.202729 |
| MT2A | metallothionein 2A | 0.147495 |
| TMSB10 | thymosin beta 10 | 0.143187 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.126663 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.119516 |
| DST | dystonin | 0.117397 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.102903 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0985226 |
| FLNB | filamin B, beta | 0.0923456 |
| LDHA | lactate dehydrogenase A | 0.0921157 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0910452 |
| MT1X | metallothionein 1X | 0.0787884 |
| TP63 | tumor protein p63 | 0.078678 |
| VIM | vimentin | 0.0784234 |
| TXNRD1 | thioredoxin reductase 1 | 0.0769956 |
| RGS4 | regulator of G-protein signaling 4 | 0.0751081 |
| PODXL | podocalyxin-like | 0.0734223 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0721095 |
| RAI1 | retinoic acid induced 1 | 0.0705432 |
| CMIP | c-Maf inducing protein | 0.0688991 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | 0.068604 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0680371 |
| PRDX1 | peroxiredoxin 1 | 0.065474 |
| PDE10A | phosphodiesterase 10A | 0.0643144 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0621342 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0614892 |
| TNFRSF6B | tumor necrosis factor receptor superfamily, member 6b, decoy | 0.0610924 |
| ANXA2 | annexin A2 | 0.0609972 |
| CFAP299 | cilia and flagella associated protein 299 | 0.0596286 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0590263 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0566331 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0556609 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.055549 |
| RAPH1 | Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 | 0.0549559 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0501176 |
| EZR | ezrin | 0.0500082 |
| APP | amyloid beta (A4) precursor protein | 0.0494861 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0489446 |
| AREG | amphiregulin | 0.047662 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0465861 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.0463792 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0456995 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.0449824 |
| RPL3 | ribosomal protein L3 | 0.044431 |
| RAP2B | RAP2B, member of RAS oncogene family | 0.0436023 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0434593 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0434177 |
| ACTG1 | actin gamma 1 | 0.0422477 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0422219 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0417558 |
| CADM2 | cell adhesion molecule 2 | 0.0408294 |
| RPL19 | ribosomal protein L19 | 0.0405008 |
| CSMD3 | CUB and Sushi multiple domains 3 | 0.0401879 |
| CAPRIN2 | caprin family member 2 | 0.0398513 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | 0.0397617 |
| NAV1 | neuron navigator 1 | 0.039725 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.0394424 |
| KRT8 | keratin 8, type II | 0.0394115 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0384536 |
| PYGL | phosphorylase, glycogen, liver | 0.0384233 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0381256 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0377521 |
| COL5A2 | collagen, type V, alpha 2 | 0.0377077 |
| RPL23 | ribosomal protein L23 | 0.0371262 |
| TPM4 | tropomyosin 4 | 0.0366247 |
| S100A6 | S100 calcium binding protein A6 | 0.0364085 |
| RAB27B | RAB27B, member RAS oncogene family | 0.0358929 |
| SET | SET nuclear proto-oncogene | 0.0357038 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0355517 |
| SLC39A10 | solute carrier family 39 (zinc transporter), member 10 | 0.0351148 |
| HDLBP | high density lipoprotein binding protein | 0.035028 |
| HLA-B | major histocompatibility complex, class I, B | 0.0346591 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0346198 |
| RPL18A | ribosomal protein L18a | 0.0344699 |
| RPS4X | ribosomal protein S4, X-linked | 0.0344459 |
| SP100 | SP100 nuclear antigen | 0.0333057 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.033167 |
| RPL36 | ribosomal protein L36 | 0.0326233 |
| NEK10 | NIMA-related kinase 10 | 0.0320157 |
| RUNX1 | runt-related transcription factor 1 | 0.031734 |
| TXNIP | thioredoxin interacting protein | 0.0316964 |
| S100A11 | S100 calcium binding protein A11 | 0.0311593 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 0.0310086 |
| RPL12 | ribosomal protein L12 | 0.0309835 |
| MT1E | metallothionein 1E | 0.0302705 |
| ACTN1 | actinin, alpha 1 | 0.0299916 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | 0.0299096 |
| EGR1 | early growth response 1 | 0.0298906 |
| RPS3 | ribosomal protein S3 | 0.029708 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0295693 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0295586 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | 0.0294054 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.029076 |
| CD44 | CD44 molecule (Indian blood group) | 0.0288522 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | 0.0287583 |
| FER | fer (fps/fes related) tyrosine kinase | 0.0287026 |
| TGM2 | transglutaminase 2 | 0.0279589 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0278686 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.0277964 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.124833 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.107168 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0785372 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0710473 |
| CENPF | centromere protein F, 350/400kDa | -0.0595893 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0553644 |
| SPAG9 | sperm associated antigen 9 | -0.0516491 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0488867 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.048116 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0428196 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0427833 |
| MKI67 | marker of proliferation Ki-67 | -0.0411173 |
| ZNF292 | zinc finger protein 292 | -0.0408536 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0395913 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0384874 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0382077 |
| RPL35A | ribosomal protein L35a | -0.0347409 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0327857 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0324586 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0322685 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0320945 |
| RBM39 | RNA binding motif protein 39 | -0.0315863 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0315631 |
| NUP58 | nucleoporin 58 | -0.029509 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | -0.029028 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | -0.0289545 |
| SRPK2 | SRSF protein kinase 2 | -0.028505 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.028237 |
| ECT2 | epithelial cell transforming 2 | -0.0280007 |
| TUBB | tubulin, beta class I | -0.028 |
| XPO1 | exportin 1 | -0.0278999 |
| ANLN | anillin, actin binding protein | -0.0278719 |
| ANXA1 | annexin A1 | -0.0277626 |
| SBF2 | SET binding factor 2 | -0.0277124 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0275827 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0275497 |
| TMEM123 | transmembrane protein 123 | -0.0274989 |
| PKM | pyruvate kinase, muscle | -0.0263411 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0260565 |
| TPX2 | TPX2, microtubule-associated | -0.0259875 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0257981 |
| HMGB2 | high mobility group box 2 | -0.0257921 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0257157 |
| CKAP5 | cytoskeleton associated protein 5 | -0.0253274 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0249861 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0249762 |
| FNIP1 | folliculin interacting protein 1 | -0.0246104 |
| STAG2 | stromal antigen 2 | -0.0245918 |
| UHRF2 | ubiquitin-like with PHD and ring finger domains 2, E3 ubiquitin protein ligase | -0.0245909 |
| OGA | O-GlcNAcase | -0.0244031 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -0.0234306 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | -0.0233626 |
| TFRC | transferrin receptor | -0.023146 |
| USP34 | ubiquitin specific peptidase 34 | -0.0230483 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0227947 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0227539 |
| VCL | vinculin | -0.0226032 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0224135 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0220943 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0220234 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0219621 |
| CKAP2 | cytoskeleton associated protein 2 | -0.0219183 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | -0.0217433 |
| WDR45B | WD repeat domain 45B | -0.0216584 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0216529 |
| USP9X | ubiquitin specific peptidase 9, X-linked | -0.0216409 |
| CDK19 | cyclin-dependent kinase 19 | -0.0215009 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0214818 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | -0.0213673 |
| ZFR | zinc finger RNA binding protein | -0.0213336 |
| XPO7 | exportin 7 | -0.0211639 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0211532 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0211334 |
| RBM33 | RNA binding motif protein 33 | -0.0209913 |
| TMEM41B | transmembrane protein 41B | -0.0209483 |
| R3HDM1 | R3H domain containing 1 | -0.0208994 |
| VMP1 | vacuole membrane protein 1 | -0.020763 |
| ARF1 | ADP-ribosylation factor 1 | -0.0206333 |
| PHIP | pleckstrin homology domain interacting protein | -0.0205511 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0205278 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | -0.0204892 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | -0.0204803 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0204752 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | -0.0204684 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0204544 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | -0.0203826 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0203774 |
| TUBA1B | tubulin, alpha 1b | -0.0203651 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | -0.0202036 |
| PCM1 | pericentriolar material 1 | -0.0200988 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | -0.0200926 |
| CLTC | clathrin, heavy chain (Hc) | -0.0200319 |
| PTBP2 | polypyrimidine tract binding protein 2 | -0.020022 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0198724 |
| SRGN | serglycin | -0.0198535 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | -0.0198514 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0197057 |
| TPR | translocated promoter region, nuclear basket protein | -0.0196449 |
| PTK2 | protein tyrosine kinase 2 | -0.019609 |
| MATR3 | matrin 3 | -0.0195911 |
