| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | vincristine perturbation in NCI-H2030 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the vincristine_NCI-H2030 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.128816 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.108065 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.0754381 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0741519 |
| RPL3 | ribosomal protein L3 | 0.072343 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0654781 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0640087 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0619381 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0582006 |
| MT2A | metallothionein 2A | 0.0546553 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0459002 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0442713 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.043673 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.040631 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0398068 |
| TPM3 | tropomyosin 3 | 0.0394111 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0376023 |
| MCL1 | myeloid cell leukemia 1 | 0.0354035 |
| FLNA | filamin A, alpha | 0.0347758 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.0342635 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0330607 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0325041 |
| APP | amyloid beta (A4) precursor protein | 0.0313889 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0304189 |
| ACTN1 | actinin, alpha 1 | 0.0302139 |
| RPL18A | ribosomal protein L18a | 0.0290165 |
| PCBP2 | poly(rC) binding protein 2 | 0.0289249 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | 0.0279411 |
| LDHA | lactate dehydrogenase A | 0.0275431 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0271331 |
| INHBA | inhibin, beta A | 0.0264183 |
| CANX | calnexin | 0.0260137 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | 0.0256897 |
| FLNB | filamin B, beta | 0.0253818 |
| FGB | fibrinogen beta chain | 0.0253543 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0253476 |
| MSN | moesin | 0.0241261 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0240409 |
| WDR43 | WD repeat domain 43 | 0.0236198 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0231847 |
| BRD2 | bromodomain containing 2 | 0.0230173 |
| COTL1 | coactosin-like F-actin binding protein 1 | 0.0226084 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0222131 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.021466 |
| HDGF | hepatoma-derived growth factor | 0.0209755 |
| YBX3 | Y box binding protein 3 | 0.0209639 |
| RPL18 | ribosomal protein L18 | 0.020764 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | 0.0206873 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0206285 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0206201 |
| PTK2 | protein tyrosine kinase 2 | 0.0204838 |
| RPS4X | ribosomal protein S4, X-linked | 0.020252 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0196223 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0191961 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.019007 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0186501 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0184593 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0180922 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0180103 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0177942 |
| TPD52 | tumor protein D52 | 0.0177841 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.0174127 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0172366 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0171672 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0171584 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0171131 |
| KRT18 | keratin 18, type I | 0.0171092 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0170235 |
| YTHDC1 | YTH domain containing 1 | 0.0168671 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0168073 |
| KLF6 | Kruppel-like factor 6 | 0.0163481 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0163433 |
| HNRNPH3 | heterogeneous nuclear ribonucleoprotein H3 (2H9) | 0.016251 |
| USP3 | ubiquitin specific peptidase 3 | 0.0162182 |
| RTN4 | reticulon 4 | 0.0161335 |
| HDLBP | high density lipoprotein binding protein | 0.0159873 |
| EPG5 | ectopic P-granules autophagy protein 5 homolog (C. elegans) | 0.0159399 |
| RBM39 | RNA binding motif protein 39 | 0.0158993 |
| YBX1 | Y box binding protein 1 | 0.015749 |
| NPTN | neuroplastin | 0.015715 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0156046 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0151793 |
| ERBIN | erbb2 interacting protein | 0.0150426 |
| RBM25 | RNA binding motif protein 25 | 0.0150339 |
| MAP1B | microtubule-associated protein 1B | 0.0150313 |
| CHD4 | chromodomain helicase DNA binding protein 4 | 0.0148834 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0148499 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0147548 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0147175 |
| HYCC2 | hyccin PI4KA lipid kinase complex subunit 2 | 0.0146851 |
| CTBP2 | C-terminal binding protein 2 | 0.0144842 |
| SON | SON DNA binding protein | 0.0144698 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0143837 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.014223 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0140746 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0138645 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0138385 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0137399 |
| NEK7 | NIMA-related kinase 7 | 0.0137062 |
| FOXO3 | forkhead box O3 | 0.0136603 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.26563 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.157959 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.133757 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.114091 |
| VIM | vimentin | -0.11259 |
| IGF2 | insulin-like growth factor 2 | -0.0823483 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.078055 |
| PM20D1 | peptidase M20 domain containing 1 | -0.0737438 |
| PYGL | phosphorylase, glycogen, liver | -0.0695166 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0565343 |
| RAD51B | RAD51 paralog B | -0.0522927 |
| GRAMD1B | GRAM domain containing 1B | -0.0517832 |
| DOCK4 | dedicator of cytokinesis 4 | -0.048002 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0445732 |
| S100A6 | S100 calcium binding protein A6 | -0.0428215 |
| OSMR | oncostatin M receptor | -0.0413864 |
| IER3 | immediate early response 3 | -0.0408866 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0408232 |
| RPL35A | ribosomal protein L35a | -0.0396477 |
| RPL31 | ribosomal protein L31 | -0.0392184 |
| TMSB10 | thymosin beta 10 | -0.038424 |
| PTMA | prothymosin, alpha | -0.0374834 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0366046 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | -0.035456 |
| EFNA5 | ephrin-A5 | -0.0353215 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0350377 |
| EHBP1 | EH domain binding protein 1 | -0.0343266 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0343201 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0339357 |
| RPS25 | ribosomal protein S25 | -0.033489 |
| RPS29 | ribosomal protein S29 | -0.0329719 |
| BICC1 | BicC family RNA binding protein 1 | -0.0318143 |
| RPS27A | ribosomal protein S27a | -0.0316692 |
| SVIL | supervillin | -0.031601 |
| NHSL1 | NHS-like 1 | -0.0314226 |
| KYNU | kynureninase | -0.0310387 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0309594 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0305007 |
| FTL | ferritin, light polypeptide | -0.0302182 |
| NEBL | nebulette | -0.0300722 |
| TUBB | tubulin, beta class I | -0.0300004 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0299883 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0295859 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0295258 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0286148 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0282298 |
| GLIS3 | GLIS family zinc finger 3 | -0.0279282 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | -0.0277971 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0277482 |
| PKM | pyruvate kinase, muscle | -0.0274657 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0273813 |
| CMIP | c-Maf inducing protein | -0.0271654 |
| UTRN | utrophin | -0.0271474 |
| VCL | vinculin | -0.0271419 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0269212 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0268185 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0264421 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0262145 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0258284 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0247511 |
| TUBA1B | tubulin, alpha 1b | -0.0242226 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0235479 |
| ASPH | aspartate beta-hydroxylase | -0.0234399 |
| EGR1 | early growth response 1 | -0.0233216 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | -0.0229979 |
| ENO1 | enolase 1, (alpha) | -0.0229848 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0228034 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0227858 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | -0.0227454 |
| NNMT | nicotinamide N-methyltransferase | -0.0223547 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0222717 |
| SNX14 | sorting nexin 14 | -0.0219597 |
| CUX1 | cut-like homeobox 1 | -0.0211329 |
| TPM4 | tropomyosin 4 | -0.0210061 |
| VMP1 | vacuole membrane protein 1 | -0.0207148 |
| RPL37A | ribosomal protein L37a | -0.020356 |
| ANGPTL4 | angiopoietin-like 4 | -0.0198516 |
| AHR | aryl hydrocarbon receptor | -0.019835 |
| USP34 | ubiquitin specific peptidase 34 | -0.0198043 |
| RPS3 | ribosomal protein S3 | -0.0197178 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.019715 |
| RPS24 | ribosomal protein S24 | -0.0197107 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0193496 |
| COX4I1 | cytochrome c oxidase subunit IV isoform 1 | -0.0191971 |
| ATXN1 | ataxin 1 | -0.0191889 |
| HLA-B | major histocompatibility complex, class I, B | -0.0187619 |
| LAMB1 | laminin, beta 1 | -0.0187437 |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 | -0.0187248 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -0.0186712 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0180589 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0178374 |
| RPS12 | ribosomal protein S12 | -0.0175247 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0173586 |
| HMGA2 | high mobility group AT-hook 2 | -0.0172434 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0170617 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0169941 |
| NF1 | neurofibromin 1 | -0.0169406 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0168788 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0167933 |
| TNRC6B | trinucleotide repeat containing 6B | -0.0166451 |
