| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | vincristine perturbation in NCI-H2347 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the vincristine_NCI-H2347 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.209922 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.186211 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.174557 |
| LDHA | lactate dehydrogenase A | 0.154811 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.130322 |
| POTEF | POTE ankyrin domain family, member F | 0.0816678 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0787985 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0749156 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0728033 |
| ENO1 | enolase 1, (alpha) | 0.0696307 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0695065 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0591268 |
| KRT7 | keratin 7, type II | 0.056157 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0533807 |
| RPL3 | ribosomal protein L3 | 0.0529191 |
| MKI67 | marker of proliferation Ki-67 | 0.0519647 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0517207 |
| RPS4X | ribosomal protein S4, X-linked | 0.0510937 |
| NAV2 | neuron navigator 2 | 0.0506431 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.050441 |
| NDRG1 | N-myc downstream regulated 1 | 0.0498322 |
| CENPF | centromere protein F, 350/400kDa | 0.0474012 |
| RPL32 | ribosomal protein L32 | 0.0461624 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0454829 |
| KRT18 | keratin 18, type I | 0.0448451 |
| VEGFA | vascular endothelial growth factor A | 0.0446418 |
| EGR1 | early growth response 1 | 0.0444346 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | 0.0439086 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0438486 |
| PCBP2 | poly(rC) binding protein 2 | 0.0438428 |
| PLEC | plectin | 0.0423577 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0421105 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0419713 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.040322 |
| UBC | ubiquitin C | 0.0400669 |
| RPL8 | ribosomal protein L8 | 0.0398506 |
| HMGA1 | high mobility group AT-hook 1 | 0.0395307 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0392774 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0392546 |
| AREG | amphiregulin | 0.0384339 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0383809 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0373673 |
| BRD2 | bromodomain containing 2 | 0.0372265 |
| RYBP | RING1 and YY1 binding protein | 0.0367421 |
| SGMS2 | sphingomyelin synthase 2 | 0.0358187 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0357508 |
| YBX1 | Y box binding protein 1 | 0.035685 |
| ARRDC3 | arrestin domain containing 3 | 0.0355661 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0352223 |
| IFITM3 | interferon induced transmembrane protein 3 | 0.0346641 |
| PLAU | plasminogen activator, urokinase | 0.0342657 |
| G0S2 | G0/G1 switch 2 | 0.0338446 |
| DTNA | dystrobrevin, alpha | 0.0335657 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0335471 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0335469 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0334977 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0333947 |
| MSN | moesin | 0.0329044 |
| FAM13A | family with sequence similarity 13, member A | 0.0317534 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0316316 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0312225 |
| RPLP0 | ribosomal protein, large, P0 | 0.0311029 |
| SP100 | SP100 nuclear antigen | 0.0308895 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0305833 |
| SQSTM1 | sequestosome 1 | 0.0303604 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0302258 |
| KRT19 | keratin 19, type I | 0.0300806 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.0295411 |
| MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | 0.0295292 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | 0.0294915 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0291151 |
| EZR | ezrin | 0.0287434 |
| HDAC9 | histone deacetylase 9 | 0.0287426 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0287064 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.028545 |
| NPTN | neuroplastin | 0.0283994 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0282535 |
| MANF | mesencephalic astrocyte-derived neurotrophic factor | 0.0282251 |
| HDGF | hepatoma-derived growth factor | 0.0281281 |
| MX1 | MX dynamin-like GTPase 1 | 0.0276352 |
| RPL18 | ribosomal protein L18 | 0.0272687 |
| ASTN2 | astrotactin 2 | 0.0271098 |
| CALR | calreticulin | 0.0270269 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0268917 |
| SDC4 | syndecan 4 | 0.0268281 |
| FTL | ferritin, light polypeptide | 0.0263105 |
| DEK | DEK proto-oncogene | 0.0257636 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0254791 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0251066 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0249955 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0248833 |
| VGLL3 | vestigial-like family member 3 | 0.0243573 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.024107 |
| GPX4 | glutathione peroxidase 4 | 0.0241053 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | 0.0240591 |
| IFITM1 | interferon induced transmembrane protein 1 | 0.0239896 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0234891 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.022985 |
| IRF1 | interferon regulatory factor 1 | 0.0229149 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0225872 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.108934 |
| RPL35A | ribosomal protein L35a | -0.086994 |
| RPS29 | ribosomal protein S29 | -0.0816722 |
| FN1 | fibronectin 1 | -0.0814125 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0789994 |
| LAMB3 | laminin, beta 3 | -0.0740516 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0715479 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0607254 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0598565 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0583394 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0561008 |
| RPL37A | ribosomal protein L37a | -0.0543665 |
| LAMC2 | laminin, gamma 2 | -0.0531324 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0518275 |
| RPL31 | ribosomal protein L31 | -0.0508174 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0467775 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0464391 |
| HLA-B | major histocompatibility complex, class I, B | -0.0458811 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0445821 |
| RPS27A | ribosomal protein S27a | -0.043834 |
| RPS13 | ribosomal protein S13 | -0.0415933 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0408062 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0407959 |
| CAVIN1 | caveolae associated protein 1 | -0.0399539 |
| RPL9 | ribosomal protein L9 | -0.0388197 |
| RAI14 | retinoic acid induced 14 | -0.0387992 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0384966 |
| RPL38 | ribosomal protein L38 | -0.0382774 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0380613 |
| NF1 | neurofibromin 1 | -0.0374655 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0368847 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0359447 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0349362 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0344903 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | -0.0344537 |
| TMEM165 | transmembrane protein 165 | -0.0344499 |
| CEP350 | centrosomal protein 350kDa | -0.0340855 |
| RPS8 | ribosomal protein S8 | -0.0340167 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0338422 |
| MYO1E | myosin IE | -0.0333133 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0330657 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0325392 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | -0.0324732 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0322782 |
| TUBB | tubulin, beta class I | -0.0317257 |
| ACTG1 | actin gamma 1 | -0.0316914 |
| MAP4 | microtubule-associated protein 4 | -0.0316908 |
| FBXO32 | F-box protein 32 | -0.0315519 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0315298 |
| CD2AP | CD2-associated protein | -0.0313707 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0310315 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0308769 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0307329 |
| NCOA2 | nuclear receptor coactivator 2 | -0.0300091 |
| JMJD1C | jumonji domain containing 1C | -0.0298071 |
| AOPEP | aminopeptidase O (putative) | -0.0296775 |
| CUX1 | cut-like homeobox 1 | -0.0294774 |
| FBXO34 | F-box protein 34 | -0.029141 |
| LMO7 | LIM domain 7 | -0.0285394 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.0285263 |
| F11R | F11 receptor | -0.0284529 |
| VIM | vimentin | -0.0280227 |
| RPS24 | ribosomal protein S24 | -0.0277641 |
| OGA | O-GlcNAcase | -0.027724 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0276326 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0276131 |
| TPR | translocated promoter region, nuclear basket protein | -0.0271652 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0268288 |
| NUMB | numb homolog (Drosophila) | -0.0266299 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0264042 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -0.0263204 |
| CLTC | clathrin, heavy chain (Hc) | -0.0261324 |
| KPNB1 | karyopherin (importin) beta 1 | -0.026059 |
| RBM25 | RNA binding motif protein 25 | -0.025868 |
| RPL34 | ribosomal protein L34 | -0.0257127 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0254623 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0254192 |
| CAB39 | calcium binding protein 39 | -0.0247737 |
| ZHX2 | zinc fingers and homeoboxes 2 | -0.0246461 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0245375 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0243905 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.024233 |
| H3-3B | H3.3 histone B | -0.024194 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0240314 |
| FNBP4 | formin binding protein 4 | -0.0239511 |
| RASA2 | RAS p21 protein activator 2 | -0.0237717 |
| RPS17 | ribosomal protein S17 | -0.0234124 |
| ANO10 | anoctamin 10 | -0.023357 |
| RCOR1 | REST corepressor 1 | -0.0232731 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0232599 |
| MSI2 | musashi RNA-binding protein 2 | -0.0229251 |
| SLMAP | sarcolemma associated protein | -0.0227906 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0226827 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0226279 |
| UBAP1 | ubiquitin associated protein 1 | -0.0225521 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0225316 |
| CDYL | chromodomain protein, Y-like | -0.0223075 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0220417 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -0.0220231 |
| VEZT | vezatin, adherens junctions transmembrane protein | -0.0220153 |
