vincristine_NCI-H596 Gene Set
Genes
51 genes differentially expressed following the vincristine_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
AKAP12
|
A kinase (PRKA) anchor protein 12
|
0.402165
|
|
TMSB10
|
thymosin beta 10
|
0.177988
|
|
LDHA
|
lactate dehydrogenase A
|
0.15939
|
|
RPL35A
|
ribosomal protein L35a
|
0.140715
|
|
POTEF
|
POTE ankyrin domain family, member F
|
0.122038
|
|
RPS16
|
ribosomal protein S16
|
0.120636
|
|
GAPDH
|
glyceraldehyde-3-phosphate dehydrogenase
|
0.119693
|
|
PITPNC1
|
phosphatidylinositol transfer protein, cytoplasmic 1
|
0.112461
|
|
HSPA5
|
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
|
0.102615
|
|
EGFR
|
epidermal growth factor receptor
|
0.0884198
|
|
SMAD3
|
SMAD family member 3
|
0.087539
|
|
SFTPA2
|
surfactant protein A2
|
0.0697854
|
|
MYH9
|
myosin, heavy chain 9, non-muscle
|
0.0568189
|
|
TPT1
|
tumor protein, translationally-controlled 1
|
0.0484641
|
|
LMO7
|
LIM domain 7
|
0.0454331
|
|
CALM2
|
calmodulin 2 (phosphorylase kinase, delta)
|
0.036886
|
|
ACTG1
|
actin gamma 1
|
0.034476
|
|
RPL23
|
ribosomal protein L23
|
0.0334785
|
|
PTMA
|
prothymosin, alpha
|
0.0281198
|
|
PCBP2
|
poly(rC) binding protein 2
|
0.0241055
|
|
MYO1E
|
myosin IE
|
0.0183404
|
|
CANX
|
calnexin
|
0.0175852
|
|
RPL12
|
ribosomal protein L12
|
0.0137831
|
|
LAMB3
|
laminin, beta 3
|
0.0133393
|
|
YBX3
|
Y box binding protein 3
|
0.0133241
|
|
RPS6
|
ribosomal protein S6
|
0.0119303
|
|
PRKCA
|
protein kinase C, alpha
|
0.011218
|
|
NKD1
|
naked cuticle homolog 1 (Drosophila)
|
0.00845779
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
HSP90AA1
|
heat shock protein 90kDa alpha (cytosolic), class A member 1
|
-0.207531
|
|
FN1
|
fibronectin 1
|
-0.144689
|
|
NDRG1
|
N-myc downstream regulated 1
|
-0.116629
|
|
HSP90AB1
|
heat shock protein 90kDa alpha (cytosolic), class B member 1
|
-0.114435
|
|
B2M
|
beta-2-microglobulin
|
-0.111775
|
|
ANXA2
|
annexin A2
|
-0.106857
|
|
FNDC3B
|
fibronectin type III domain containing 3B
|
-0.106362
|
|
HSP90B1
|
heat shock protein 90kDa beta (Grp94), member 1
|
-0.106027
|
|
VIM
|
vimentin
|
-0.103763
|
|
MMAB
|
methylmalonic aciduria (cobalamin deficiency) cblB type
|
-0.0906008
|
|
DSCAM
|
Down syndrome cell adhesion molecule
|
-0.0728741
|
|
USP34
|
ubiquitin specific peptidase 34
|
-0.0637148
|
|
RPL37A
|
ribosomal protein L37a
|
-0.0483097
|
|
HERC4
|
HECT and RLD domain containing E3 ubiquitin protein ligase 4
|
-0.0441537
|
|
P4HA1
|
prolyl 4-hydroxylase, alpha polypeptide I
|
-0.0362721
|
|
PABPC1
|
poly(A) binding protein, cytoplasmic 1
|
-0.0296935
|
|
FTL
|
ferritin, light polypeptide
|
-0.0235742
|
|
EZR
|
ezrin
|
-0.0227801
|
|
RPS12
|
ribosomal protein S12
|
-0.0209018
|
|
ASPH
|
aspartate beta-hydroxylase
|
-0.0153868
|
|
ERO1A
|
endoplasmic reticulum oxidoreductase 1 alpha
|
-0.011907
|
|
PARD3
|
par-3 family cell polarity regulator
|
-0.00883794
|
|
LAMC2
|
laminin, gamma 2
|
-0.0020186
|
