| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | vincristine perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the vincristine_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.113205 |
| HDAC9 | histone deacetylase 9 | 0.0752272 |
| RPL3 | ribosomal protein L3 | 0.0735035 |
| EZR | ezrin | 0.0674917 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0648988 |
| FLNB | filamin B, beta | 0.0648048 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0511739 |
| PDGFC | platelet derived growth factor C | 0.0488668 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0450905 |
| LDHA | lactate dehydrogenase A | 0.0444376 |
| EXT1 | exostosin glycosyltransferase 1 | 0.04327 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0430836 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0426818 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0419764 |
| TPM4 | tropomyosin 4 | 0.0407097 |
| RTN4 | reticulon 4 | 0.0382253 |
| ZNF608 | zinc finger protein 608 | 0.0371108 |
| AHNAK | AHNAK nucleoprotein | 0.0355625 |
| MYOF | myoferlin | 0.0331273 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0327104 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0321528 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0312305 |
| CREB5 | cAMP responsive element binding protein 5 | 0.0291306 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0290405 |
| DUSP4 | dual specificity phosphatase 4 | 0.0287377 |
| ANXA1 | annexin A1 | 0.0285138 |
| BMP2K | BMP2 inducible kinase | 0.0278099 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0275664 |
| LOXL3 | lysyl oxidase-like 3 | 0.0271629 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.0268932 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0251178 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0250203 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0245302 |
| RAB27B | RAB27B, member RAS oncogene family | 0.0231777 |
| TMCO3 | transmembrane and coiled-coil domains 3 | 0.0228233 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0227534 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0224088 |
| JMJD1C | jumonji domain containing 1C | 0.0218615 |
| TXNIP | thioredoxin interacting protein | 0.0215835 |
| HSPA8 | heat shock 70kDa protein 8 | 0.021389 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0209752 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | 0.0204834 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0201134 |
| SGMS2 | sphingomyelin synthase 2 | 0.0195757 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 | 0.0193754 |
| RUSC2 | RUN and SH3 domain containing 2 | 0.0192442 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0190734 |
| UBC | ubiquitin C | 0.0190163 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0184569 |
| TACC2 | transforming, acidic coiled-coil containing protein 2 | 0.0179487 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0175176 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0175017 |
| FAT1 | FAT atypical cadherin 1 | 0.0174972 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0172467 |
| CCSER2 | coiled-coil serine-rich protein 2 | 0.016698 |
| ANLN | anillin, actin binding protein | 0.0165799 |
| EML4 | echinoderm microtubule associated protein like 4 | 0.0164929 |
| ANK2 | ankyrin 2, neuronal | 0.0164402 |
| FER1L6 | fer-1-like family member 6 | 0.0161448 |
| PRPF38B | pre-mRNA processing factor 38B | 0.0160881 |
| SGMS1 | sphingomyelin synthase 1 | 0.0157951 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0157342 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | 0.015682 |
| CLIC4 | chloride intracellular channel 4 | 0.0156261 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0150631 |
| CPNE1 | copine I | 0.0150561 |
| ATP9B | ATPase, class II, type 9B | 0.0150293 |
| DUSP16 | dual specificity phosphatase 16 | 0.0147278 |
| FNIP1 | folliculin interacting protein 1 | 0.0146053 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0144873 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0144167 |
| GLI2 | GLI family zinc finger 2 | 0.0144042 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.0142728 |
| ZNF217 | zinc finger protein 217 | 0.0142385 |
| XIRP2 | xin actin binding repeat containing 2 | 0.0131227 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0130782 |
| RPL4 | ribosomal protein L4 | 0.0130682 |
| FAM91A1 | family with sequence similarity 91, member A1 | 0.0125129 |
| JUN | jun proto-oncogene | 0.0124693 |
| YAP1 | Yes-associated protein 1 | 0.0123779 |
| CYTH3 | cytohesin 3 | 0.0122674 |
| MAST2 | microtubule associated serine/threonine kinase 2 | 0.0122267 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0122184 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0118863 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0118415 |
| LIMD1 | LIM domains containing 1 | 0.0118384 |
| INTS6 | integrator complex subunit 6 | 0.0118282 |
| PKM | pyruvate kinase, muscle | 0.0118259 |
| ATOSA | atos homolog A | 0.0118174 |
| TASOR2 | transcription activation suppressor family member 2 | 0.0118054 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0117861 |
| STX18 | syntaxin 18 | 0.0117649 |
| PTPN11 | protein tyrosine phosphatase, non-receptor type 11 | 0.011762 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.011758 |
| CTBP2 | C-terminal binding protein 2 | 0.0116966 |
| TUFT1 | tuftelin 1 | 0.0116831 |
| CYFIP1 | cytoplasmic FMR1 interacting protein 1 | 0.0116767 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.0116222 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0115516 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0113982 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.216422 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.150076 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0816522 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0781369 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0737572 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.0735725 |
| RPS6 | ribosomal protein S6 | -0.0668773 |
| FOXP1 | forkhead box P1 | -0.0621476 |
| RPL35A | ribosomal protein L35a | -0.0524279 |
| CAMKMT | calmodulin-lysine N-methyltransferase | -0.0495018 |
| VCL | vinculin | -0.0492092 |
| ACTG1 | actin gamma 1 | -0.0476643 |
| TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b | -0.0446946 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.0440349 |
| RPLP1 | ribosomal protein, large, P1 | -0.0430346 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.042517 |
| NFIA | nuclear factor I/A | -0.0393954 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0387712 |
| RPS8 | ribosomal protein S8 | -0.038224 |
| CACNB4 | calcium channel, voltage-dependent, beta 4 subunit | -0.035485 |
| RPLP0 | ribosomal protein, large, P0 | -0.0353262 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0352521 |
| RPL34 | ribosomal protein L34 | -0.0342434 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0337575 |
| PFN1 | profilin 1 | -0.0328129 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0311121 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0309 |
| RPS19 | ribosomal protein S19 | -0.0300363 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0293809 |
| CENPF | centromere protein F, 350/400kDa | -0.0293167 |
| RPL12 | ribosomal protein L12 | -0.0290943 |
| RPS23 | ribosomal protein S23 | -0.029045 |
| RPLP2 | ribosomal protein, large, P2 | -0.0288642 |
| RPL26 | ribosomal protein L26 | -0.0283139 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0274448 |
| RPL36 | ribosomal protein L36 | -0.0268919 |
| S100A4 | S100 calcium binding protein A4 | -0.0267473 |
| RPL9 | ribosomal protein L9 | -0.0266567 |
| NAV2 | neuron navigator 2 | -0.0264266 |
| RPS21 | ribosomal protein S21 | -0.0264171 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0256284 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0250919 |
| RPS14 | ribosomal protein S14 | -0.0243898 |
| B2M | beta-2-microglobulin | -0.0241084 |
| RPS24 | ribosomal protein S24 | -0.0241036 |
| RPL37A | ribosomal protein L37a | -0.0239237 |
| SMC3 | structural maintenance of chromosomes 3 | -0.0237587 |
| FTL | ferritin, light polypeptide | -0.0236183 |
| DUSP6 | dual specificity phosphatase 6 | -0.0233676 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0227945 |
| RPS3 | ribosomal protein S3 | -0.0226329 |
| S100A9 | S100 calcium binding protein A9 | -0.0224826 |
| GPHN | gephyrin | -0.0223486 |
| RPS27A | ribosomal protein S27a | -0.0220332 |
| NEBL | nebulette | -0.0219844 |
| TPI1 | triosephosphate isomerase 1 | -0.0218525 |
| EXOC6B | exocyst complex component 6B | -0.0217501 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0217439 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0217114 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0216628 |
| TUBA1B | tubulin, alpha 1b | -0.0216521 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0214452 |
| RPL11 | ribosomal protein L11 | -0.0214207 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0214205 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0213852 |
| S100A6 | S100 calcium binding protein A6 | -0.0209435 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0208199 |
| POTEF | POTE ankyrin domain family, member F | -0.0206449 |
| RPS13 | ribosomal protein S13 | -0.0206384 |
| RPL23 | ribosomal protein L23 | -0.0204065 |
| BMP10 | bone morphogenetic protein 10 | -0.0203043 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0200586 |
| EHBP1 | EH domain binding protein 1 | -0.0197897 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0195731 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0194729 |
| TUBB | tubulin, beta class I | -0.0194487 |
| RPL31 | ribosomal protein L31 | -0.0189121 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0186503 |
| GNAS | GNAS complex locus | -0.0183917 |
| RPS25 | ribosomal protein S25 | -0.0183501 |
| PRDX2 | peroxiredoxin 2 | -0.0180725 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0180449 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.017698 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 | -0.0176712 |
| RPL27A | ribosomal protein L27a | -0.0176565 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | -0.0168723 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0165267 |
| RPL7A | ribosomal protein L7a | -0.0163983 |
| VDAC1 | voltage-dependent anion channel 1 | -0.016389 |
| CBX3 | chromobox homolog 3 | -0.0163493 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0163491 |
| HMGB1 | high mobility group box 1 | -0.0162666 |
| NBEA | neurobeachin | -0.0160994 |
| TMSB10 | thymosin beta 10 | -0.0160597 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0159716 |
| RPL19 | ribosomal protein L19 | -0.0159021 |
| GOLGA4 | golgin A4 | -0.0158821 |
| RPL36A | ribosomal protein L36a | -0.0154827 |
| RPL30 | ribosomal protein L30 | -0.0153005 |
| CYB5B | cytochrome b5 type B (outer mitochondrial membrane) | -0.0152805 |
