| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | vincristine perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the vincristine_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.179703 |
| LDHA | lactate dehydrogenase A | 0.169777 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.145262 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.1098 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0998663 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0917678 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0905389 |
| RPS4X | ribosomal protein S4, X-linked | 0.0884525 |
| HDAC9 | histone deacetylase 9 | 0.0877564 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0872006 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0814203 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0786732 |
| STC1 | stanniocalcin 1 | 0.0762682 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0719246 |
| MSN | moesin | 0.0706423 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0593026 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0551919 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0499574 |
| NAV2 | neuron navigator 2 | 0.0493929 |
| DST | dystonin | 0.0472856 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.046485 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0458916 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0451949 |
| PLIN2 | perilipin 2 | 0.0442288 |
| CANX | calnexin | 0.0439603 |
| AHNAK | AHNAK nucleoprotein | 0.0428642 |
| RPL3 | ribosomal protein L3 | 0.0426495 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | 0.0418321 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0408204 |
| RND3 | Rho family GTPase 3 | 0.0394772 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0393713 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0391934 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0383714 |
| VEGFA | vascular endothelial growth factor A | 0.0366642 |
| CALR | calreticulin | 0.0361437 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0361309 |
| ANXA2 | annexin A2 | 0.0351609 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.034349 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.0342819 |
| APP | amyloid beta (A4) precursor protein | 0.0332695 |
| NDRG1 | N-myc downstream regulated 1 | 0.0330791 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0327622 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0324631 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0323511 |
| RUNX1 | runt-related transcription factor 1 | 0.0322039 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0320751 |
| JMJD1C | jumonji domain containing 1C | 0.0319839 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0315317 |
| PGK1 | phosphoglycerate kinase 1 | 0.0310099 |
| SMAD3 | SMAD family member 3 | 0.0301833 |
| MAP1B | microtubule-associated protein 1B | 0.0300763 |
| ENO1 | enolase 1, (alpha) | 0.0297898 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0292963 |
| PCBP2 | poly(rC) binding protein 2 | 0.0292043 |
| FN1 | fibronectin 1 | 0.0290407 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0288753 |
| MT1X | metallothionein 1X | 0.0288167 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0287999 |
| EGR1 | early growth response 1 | 0.0285913 |
| TMSB4X | thymosin beta 4, X-linked | 0.0276238 |
| ARRDC3 | arrestin domain containing 3 | 0.026743 |
| MX1 | MX dynamin-like GTPase 1 | 0.0265523 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0265372 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0264136 |
| OPTN | optineurin | 0.0261257 |
| ICAM1 | intercellular adhesion molecule 1 | 0.0261205 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0261125 |
| ZNF292 | zinc finger protein 292 | 0.0258983 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0258389 |
| TPM3 | tropomyosin 3 | 0.0256933 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0256166 |
| CDCP1 | CUB domain containing protein 1 | 0.0254246 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0253581 |
| CREB5 | cAMP responsive element binding protein 5 | 0.0252508 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0247805 |
| KLF6 | Kruppel-like factor 6 | 0.0246569 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0246222 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0242507 |
| MKI67 | marker of proliferation Ki-67 | 0.0242238 |
| SFTPA2 | surfactant protein A2 | 0.0241238 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0239243 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0239146 |
| SFRP1 | secreted frizzled-related protein 1 | 0.0238922 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0237091 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | 0.0236355 |
| SNX9 | sorting nexin 9 | 0.02341 |
| TXNIP | thioredoxin interacting protein | 0.023338 |
| UBC | ubiquitin C | 0.0233304 |
| RAI1 | retinoic acid induced 1 | 0.0232885 |
| GOLGA4 | golgin A4 | 0.0231965 |
| LAMP2 | lysosomal-associated membrane protein 2 | 0.0231382 |
| OGA | O-GlcNAcase | 0.022993 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0229355 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0227306 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.022601 |
| ATXN1 | ataxin 1 | 0.0224502 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.022417 |
| FLNA | filamin A, alpha | 0.0224095 |
| YBX1 | Y box binding protein 1 | 0.0223971 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0222821 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TPT1 | tumor protein, translationally-controlled 1 | -0.122056 |
| IER3 | immediate early response 3 | -0.110232 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0889929 |
| RPL35A | ribosomal protein L35a | -0.0788737 |
| RPL37A | ribosomal protein L37a | -0.0774807 |
| PTMA | prothymosin, alpha | -0.0716968 |
| RPS24 | ribosomal protein S24 | -0.0592714 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0519372 |
| VIM | vimentin | -0.0519198 |
| RPL31 | ribosomal protein L31 | -0.0513802 |
| FRMD4A | FERM domain containing 4A | -0.0489005 |
| HLA-B | major histocompatibility complex, class I, B | -0.0477667 |
| RPS27A | ribosomal protein S27a | -0.0449834 |
| RPL38 | ribosomal protein L38 | -0.0437314 |
| PDE10A | phosphodiesterase 10A | -0.0425558 |
| CADM1 | cell adhesion molecule 1 | -0.0420703 |
| RPS13 | ribosomal protein S13 | -0.0417611 |
| RPS23 | ribosomal protein S23 | -0.0416977 |
| RPS8 | ribosomal protein S8 | -0.0397628 |
| RPLP2 | ribosomal protein, large, P2 | -0.0393566 |
| RPL23 | ribosomal protein L23 | -0.0388135 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0381901 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.037359 |
| CTSD | cathepsin D | -0.0373269 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.036465 |
| TMEM132D | transmembrane protein 132D | -0.0351895 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0349313 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0343197 |
| RPL36A | ribosomal protein L36a | -0.0342965 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0327261 |
| RPL9 | ribosomal protein L9 | -0.0319414 |
| COL1A1 | collagen, type I, alpha 1 | -0.0314516 |
| FTL | ferritin, light polypeptide | -0.0302843 |
| VCL | vinculin | -0.0297073 |
| RPS29 | ribosomal protein S29 | -0.028845 |
| EGFR | epidermal growth factor receptor | -0.0285568 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0270408 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0255376 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0254925 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.025449 |
| TBCA | tubulin folding cofactor A | -0.0248162 |
| FRMPD4 | FERM and PDZ domain containing 4 | -0.0236099 |
| RPS15 | ribosomal protein S15 | -0.0233319 |
| HLA-A | major histocompatibility complex, class I, A | -0.0232936 |
| RPS25 | ribosomal protein S25 | -0.0230672 |
| CLMP | CXADR-like membrane protein | -0.0230639 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0227663 |
| EFNA5 | ephrin-A5 | -0.0225724 |
| INTS6 | integrator complex subunit 6 | -0.0224782 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.022448 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | -0.0224384 |
| GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A | -0.0223354 |
| FBXO11 | F-box protein 11 | -0.022106 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0217087 |
| RPL7A | ribosomal protein L7a | -0.0216524 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0213263 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0212123 |
| QKI | QKI, KH domain containing, RNA binding | -0.0210727 |
| RPS3 | ribosomal protein S3 | -0.0209316 |
| RAI14 | retinoic acid induced 14 | -0.0207879 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0207876 |
| RPL28 | ribosomal protein L28 | -0.0207196 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0206498 |
| RPS16 | ribosomal protein S16 | -0.0205938 |
| STC2 | stanniocalcin 2 | -0.0204934 |
| RPS10 | ribosomal protein S10 | -0.0203192 |
| RPL26 | ribosomal protein L26 | -0.0201248 |
| RPL34 | ribosomal protein L34 | -0.020074 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0198576 |
| ARFGAP3 | ADP-ribosylation factor GTPase activating protein 3 | -0.0193277 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0191823 |
| KAZN | kazrin, periplakin interacting protein | -0.0191399 |
| IGFBP7 | insulin-like growth factor binding protein 7 | -0.0189207 |
| RPL36 | ribosomal protein L36 | -0.018854 |
| DIAPH2 | diaphanous-related formin 2 | -0.0187675 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0186878 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.018324 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0180206 |
| CDK13 | cyclin-dependent kinase 13 | -0.0177378 |
| LRRC7 | leucine rich repeat containing 7 | -0.017591 |
| RPLP1 | ribosomal protein, large, P1 | -0.0174009 |
| FBXO32 | F-box protein 32 | -0.0173058 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0171433 |
| FAM20C | family with sequence similarity 20, member C | -0.0170779 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0170408 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0170291 |
| TUBB | tubulin, beta class I | -0.0169703 |
| SENP6 | SUMO1/sentrin specific peptidase 6 | -0.0167575 |
| CUX1 | cut-like homeobox 1 | -0.0166013 |
| DENND5B | DENN/MADD domain containing 5B | -0.016424 |
| LSAMP | limbic system-associated membrane protein | -0.0162633 |
| S100A9 | S100 calcium binding protein A9 | -0.0162142 |
| RPL5 | ribosomal protein L5 | -0.0159967 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0159876 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0158963 |
| RPS21 | ribosomal protein S21 | -0.0158022 |
| TMSB10 | thymosin beta 10 | -0.0157945 |
| BNC2 | basonuclin 2 | -0.0157219 |
| TGFB1 | transforming growth factor, beta 1 | -0.0156793 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0154808 |
