| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | vincristine perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the vincristine_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LDHA | lactate dehydrogenase A | 0.148753 |
| TMSB10 | thymosin beta 10 | 0.130198 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.124338 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.120389 |
| CD44 | CD44 molecule (Indian blood group) | 0.120095 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0886073 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0849759 |
| POTEF | POTE ankyrin domain family, member F | 0.0768172 |
| ENO1 | enolase 1, (alpha) | 0.0766039 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0759221 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0744723 |
| PKM | pyruvate kinase, muscle | 0.0728791 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0716836 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0706812 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.069971 |
| ANGPTL4 | angiopoietin-like 4 | 0.0692151 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0666348 |
| MAP1B | microtubule-associated protein 1B | 0.0660354 |
| MT2A | metallothionein 2A | 0.0636166 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.063086 |
| DTNA | dystrobrevin, alpha | 0.0627585 |
| MSN | moesin | 0.0617125 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0615317 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0602019 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0596615 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0587548 |
| SQSTM1 | sequestosome 1 | 0.0582893 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.058148 |
| MCL1 | myeloid cell leukemia 1 | 0.0580979 |
| SET | SET nuclear proto-oncogene | 0.0566111 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0565511 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0564921 |
| SDC4 | syndecan 4 | 0.0559478 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0558087 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0554276 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0550044 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.054699 |
| CPNE1 | copine I | 0.0544606 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0538183 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0521535 |
| ITGA6 | integrin, alpha 6 | 0.0520526 |
| CANX | calnexin | 0.051145 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0511268 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0506904 |
| HDAC9 | histone deacetylase 9 | 0.050175 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0499097 |
| ASPH | aspartate beta-hydroxylase | 0.0480975 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0480323 |
| AHNAK | AHNAK nucleoprotein | 0.0480184 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0478462 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0468756 |
| PCBP2 | poly(rC) binding protein 2 | 0.0467422 |
| RPL23 | ribosomal protein L23 | 0.0462685 |
| FMNL2 | formin-like 2 | 0.0461615 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0456703 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0452321 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | 0.0445297 |
| EGFR | epidermal growth factor receptor | 0.0441941 |
| SMAD3 | SMAD family member 3 | 0.0434177 |
| LIMA1 | LIM domain and actin binding 1 | 0.0429685 |
| FLNA | filamin A, alpha | 0.0429225 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0425434 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0423339 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0422989 |
| INTS6 | integrator complex subunit 6 | 0.0409511 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.040928 |
| RPS17 | ribosomal protein S17 | 0.040681 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0398377 |
| CAVIN1 | caveolae associated protein 1 | 0.03957 |
| TPI1 | triosephosphate isomerase 1 | 0.039221 |
| DST | dystonin | 0.0391788 |
| SETD5 | SET domain containing 5 | 0.0391683 |
| MYO10 | myosin X | 0.0389318 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.038856 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0385942 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | 0.0381594 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0379469 |
| PTMA | prothymosin, alpha | 0.0376375 |
| VIM | vimentin | 0.0375706 |
| UTRN | utrophin | 0.0368699 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0363303 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0353938 |
| GNAS | GNAS complex locus | 0.035102 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | 0.0341165 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0340048 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0338098 |
| DEK | DEK proto-oncogene | 0.0337177 |
| ANXA2 | annexin A2 | 0.0336152 |
| CALR | calreticulin | 0.0335536 |
| PRRC2B | proline-rich coiled-coil 2B | 0.0335126 |
| ACTG1 | actin gamma 1 | 0.0332688 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0332418 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0330108 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0329898 |
| CCND1 | cyclin D1 | 0.0329326 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0326501 |
| RPLP1 | ribosomal protein, large, P1 | 0.0322002 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0314033 |
| FRMD6 | FERM domain containing 6 | 0.0312794 |
| PRSS23 | protease, serine, 23 | 0.0311689 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ANKRD28 | ankyrin repeat domain 28 | -0.0562434 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0519166 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0507543 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0503236 |
| NF1 | neurofibromin 1 | -0.0501432 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0447067 |
| RBM39 | RNA binding motif protein 39 | -0.0407201 |
| ATM | ATM serine/threonine kinase | -0.0401665 |
| OSMR | oncostatin M receptor | -0.0366357 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0362701 |
| SMYD3 | SET and MYND domain containing 3 | -0.0358397 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0355876 |
| VCL | vinculin | -0.0353491 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | -0.0348106 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.034523 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0343052 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0339805 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0318472 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0315378 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0309781 |
| SGO2 | shugoshin 2 | -0.0288786 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0285012 |
| PIAS1 | protein inhibitor of activated STAT, 1 | -0.0273192 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0271982 |
| PUM2 | pumilio RNA-binding family member 2 | -0.026968 |
| TCERG1 | transcription elongation regulator 1 | -0.026827 |
| CCNB2 | cyclin B2 | -0.026627 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.026581 |
| CENPF | centromere protein F, 350/400kDa | -0.0263994 |
| EFNA5 | ephrin-A5 | -0.0258183 |
| GPHN | gephyrin | -0.0257941 |
| ZFAND6 | zinc finger, AN1-type domain 6 | -0.0255754 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | -0.0252849 |
| TPX2 | TPX2, microtubule-associated | -0.025184 |
| RPRD1B | regulation of nuclear pre-mRNA domain containing 1B | -0.0249179 |
| KIF4A | kinesin family member 4A | -0.0241956 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0241237 |
| HJURP | Holliday junction recognition protein | -0.0240777 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0239983 |
| PHF14 | PHD finger protein 14 | -0.0235683 |
| RAD18 | RAD18 E3 ubiquitin protein ligase | -0.0232339 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0230287 |
| KIAA1328 | KIAA1328 | -0.0229079 |
| NALCN | sodium leak channel, non selective | -0.0228551 |
| RSRC1 | arginine/serine-rich coiled-coil 1 | -0.0228337 |
| ANO10 | anoctamin 10 | -0.0226901 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0223304 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0222542 |
| ABI2 | abl-interactor 2 | -0.0222237 |
| PSMD5 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 5 | -0.0220528 |
| NKTR | natural killer cell triggering receptor | -0.0219291 |
| ATF7IP | activating transcription factor 7 interacting protein | -0.0215579 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0215318 |
| RSU1 | Ras suppressor protein 1 | -0.0214342 |
| KPNB1 | karyopherin (importin) beta 1 | -0.021297 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0212213 |
| CUX1 | cut-like homeobox 1 | -0.021051 |
| NXN | nucleoredoxin | -0.0210483 |
| KIF13A | kinesin family member 13A | -0.0210465 |
| KIF18B | kinesin family member 18B | -0.0210088 |
| PHIP | pleckstrin homology domain interacting protein | -0.0209422 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0208809 |
| STRN | striatin, calmodulin binding protein | -0.020852 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | -0.0208425 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -0.0208079 |
| ZC3H12C | zinc finger CCCH-type containing 12C | -0.0207491 |
| TUBB | tubulin, beta class I | -0.0207083 |
| PDSS2 | prenyl (decaprenyl) diphosphate synthase, subunit 2 | -0.0206145 |
| HIBADH | 3-hydroxyisobutyrate dehydrogenase | -0.0205822 |
| PCNX1 | pecanex 1 | -0.0205785 |
| POT1 | protection of telomeres 1 | -0.0205225 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0203208 |
| TUBA1C | tubulin, alpha 1c | -0.0201713 |
| EXOC6B | exocyst complex component 6B | -0.0198635 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0198609 |
| PREPL | prolyl endopeptidase-like | -0.0198588 |
| R3HDM1 | R3H domain containing 1 | -0.0197399 |
| GOLT1B | golgi transport 1B | -0.019664 |
| IGF1R | insulin-like growth factor 1 receptor | -0.019651 |
| RCOR1 | REST corepressor 1 | -0.0195707 |
| SKP1 | S-phase kinase-associated protein 1 | -0.0194555 |
| GPC6 | glypican 6 | -0.0193698 |
| CLASP2 | cytoplasmic linker associated protein 2 | -0.0193124 |
| PPP2R5C | protein phosphatase 2, regulatory subunit B', gamma | -0.0191693 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0190489 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | -0.0189659 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | -0.018939 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | -0.0187504 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | -0.0187464 |
| ZNF33A | zinc finger protein 33A | -0.0187252 |
| DHX29 | DEAH (Asp-Glu-Ala-His) box polypeptide 29 | -0.0186989 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0185392 |
| MAPKAP1 | mitogen-activated protein kinase associated protein 1 | -0.0185093 |
| USP15 | ubiquitin specific peptidase 15 | -0.0184442 |
| ZNF680 | zinc finger protein 680 | -0.0183658 |
| GLG1 | golgi glycoprotein 1 | -0.0183592 |
| YTHDC2 | YTH domain containing 2 | -0.0183534 |
| WDR26 | WD repeat domain 26 | -0.0183026 |
| CAPRIN1 | cell cycle associated protein 1 | -0.0182302 |
| CEP95 | centrosomal protein 95kDa | -0.0181056 |
