| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | vincristine perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the vincristine_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.12421 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.109725 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0938597 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.077602 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0747734 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0732979 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0556522 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | 0.0534388 |
| STC2 | stanniocalcin 2 | 0.0512215 |
| CANX | calnexin | 0.0504436 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0500266 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.04885 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0453598 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0450011 |
| RASAL2 | RAS protein activator like 2 | 0.0410157 |
| MAP1B | microtubule-associated protein 1B | 0.0405384 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0370743 |
| ASPH | aspartate beta-hydroxylase | 0.0364014 |
| MYOF | myoferlin | 0.0351759 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0350168 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.0345235 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0340402 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0326938 |
| FLNA | filamin A, alpha | 0.0318862 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0318454 |
| LOXL2 | lysyl oxidase-like 2 | 0.0314594 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0305334 |
| EGFR | epidermal growth factor receptor | 0.0301271 |
| FAT1 | FAT atypical cadherin 1 | 0.0293557 |
| S100A10 | S100 calcium binding protein A10 | 0.0285646 |
| SLC35F3 | solute carrier family 35, member F3 | 0.0285512 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0284292 |
| SMAD3 | SMAD family member 3 | 0.0273001 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.026842 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.0253537 |
| DST | dystonin | 0.0245473 |
| PRSS23 | protease, serine, 23 | 0.0244619 |
| CAPN2 | calpain 2, (m/II) large subunit | 0.023951 |
| FRMD6 | FERM domain containing 6 | 0.0237777 |
| AHNAK | AHNAK nucleoprotein | 0.0233604 |
| TPM3 | tropomyosin 3 | 0.0226864 |
| ACTG1 | actin gamma 1 | 0.0221804 |
| FAM13A | family with sequence similarity 13, member A | 0.0221294 |
| ERBIN | erbb2 interacting protein | 0.0217587 |
| PLEC | plectin | 0.0213754 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0206684 |
| RUNX1 | runt-related transcription factor 1 | 0.0204664 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0204638 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0204271 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0203213 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0201719 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0201596 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0201303 |
| RPL3 | ribosomal protein L3 | 0.0200794 |
| TMEM156 | transmembrane protein 156 | 0.0198002 |
| MCL1 | myeloid cell leukemia 1 | 0.0191575 |
| FAM107B | family with sequence similarity 107, member B | 0.0191328 |
| CTBP2 | C-terminal binding protein 2 | 0.0190889 |
| CREB5 | cAMP responsive element binding protein 5 | 0.0189518 |
| MITF | microphthalmia-associated transcription factor | 0.0189338 |
| LYST | lysosomal trafficking regulator | 0.0184932 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | 0.0184889 |
| CSGALNACT2 | chondroitin sulfate N-acetylgalactosaminyltransferase 2 | 0.0182712 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0181672 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0180507 |
| CCND1 | cyclin D1 | 0.0180487 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0176163 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0175952 |
| ATXN1 | ataxin 1 | 0.0172661 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0171894 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0169204 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | 0.0168777 |
| MRPS6 | mitochondrial ribosomal protein S6 | 0.0164715 |
| DTNA | dystrobrevin, alpha | 0.0160911 |
| POTEF | POTE ankyrin domain family, member F | 0.0160835 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0160096 |
| MANF | mesencephalic astrocyte-derived neurotrophic factor | 0.0159611 |
| FLNB | filamin B, beta | 0.0158909 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.015828 |
| STK10 | serine/threonine kinase 10 | 0.0157534 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0157001 |
| QSOX1 | quiescin Q6 sulfhydryl oxidase 1 | 0.015596 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0152561 |
| GPR39 | G protein-coupled receptor 39 | 0.0151565 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0150403 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0148417 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0147588 |
| HYOU1 | hypoxia up-regulated 1 | 0.0146079 |
| INTS6 | integrator complex subunit 6 | 0.014539 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0143102 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0141093 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.014102 |
| FOSL1 | FOS-like antigen 1 | 0.0139002 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0138724 |
| ANTXR2 | anthrax toxin receptor 2 | 0.0136511 |
| HMGA2 | high mobility group AT-hook 2 | 0.0136221 |
| APP | amyloid beta (A4) precursor protein | 0.0136124 |
| UHMK1 | U2AF homology motif (UHM) kinase 1 | 0.0135988 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0134662 |
| RND3 | Rho family GTPase 3 | 0.0134618 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.298358 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.277221 |
| FN1 | fibronectin 1 | -0.164755 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.133519 |
| NRG1 | neuregulin 1 | -0.112936 |
| PTMA | prothymosin, alpha | -0.0905051 |
| TMSB10 | thymosin beta 10 | -0.0687913 |
| GLIS3 | GLIS family zinc finger 3 | -0.0649722 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0546907 |
| FTL | ferritin, light polypeptide | -0.0465537 |
| ITGA1 | integrin, alpha 1 | -0.0455761 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0421723 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0416921 |
| TPR | translocated promoter region, nuclear basket protein | -0.0414772 |
| RUNX2 | runt-related transcription factor 2 | -0.035556 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0336278 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0333948 |
| ETV6 | ets variant 6 | -0.0331907 |
| ETV1 | ets variant 1 | -0.0328952 |
| AHR | aryl hydrocarbon receptor | -0.0314803 |
| NRP1 | neuropilin 1 | -0.0314237 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0310338 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0303626 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0303422 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.029712 |
| SMOX | spermine oxidase | -0.0289918 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0287329 |
| HMGB3 | high mobility group box 3 | -0.027282 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0271839 |
| HLA-B | major histocompatibility complex, class I, B | -0.0269478 |
| RPS21 | ribosomal protein S21 | -0.0269359 |
| RPL31 | ribosomal protein L31 | -0.0264792 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.0246112 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0241965 |
| PUM2 | pumilio RNA-binding family member 2 | -0.024021 |
| RPS6 | ribosomal protein S6 | -0.0239687 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0237886 |
| CD44 | CD44 molecule (Indian blood group) | -0.0237874 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.0237598 |
| VMP1 | vacuole membrane protein 1 | -0.023679 |
| RPL35A | ribosomal protein L35a | -0.0236443 |
| VIM | vimentin | -0.0235052 |
| UBE2K | ubiquitin-conjugating enzyme E2K | -0.0230539 |
| B2M | beta-2-microglobulin | -0.0227609 |
| AOPEP | aminopeptidase O (putative) | -0.0220952 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0220047 |
| S100A6 | S100 calcium binding protein A6 | -0.021996 |
| SQSTM1 | sequestosome 1 | -0.0219676 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0219436 |
| TUBB4B | tubulin, beta 4B class IVb | -0.021704 |
| AHRR | aryl-hydrocarbon receptor repressor | -0.0215086 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0214592 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0213905 |
| ARF4 | ADP-ribosylation factor 4 | -0.0213583 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0213246 |
| USP34 | ubiquitin specific peptidase 34 | -0.0210874 |
| PGK1 | phosphoglycerate kinase 1 | -0.0208609 |
| ADD3 | adducin 3 (gamma) | -0.0207821 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0204436 |
| RPL11 | ribosomal protein L11 | -0.0201786 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0199688 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0199192 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0198724 |
| SYT1 | synaptotagmin I | -0.0198545 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0198332 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0198285 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0195799 |
| RPL37A | ribosomal protein L37a | -0.0194878 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0192012 |
| RPS24 | ribosomal protein S24 | -0.0190824 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0190376 |
| FMN1 | formin 1 | -0.0187557 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0186915 |
| OSMR | oncostatin M receptor | -0.0185941 |
| IER3 | immediate early response 3 | -0.0185021 |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 | -0.0184593 |
| CLTC | clathrin, heavy chain (Hc) | -0.0182792 |
| CENPF | centromere protein F, 350/400kDa | -0.0178751 |
| RBM25 | RNA binding motif protein 25 | -0.0177597 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0176516 |
| RBM47 | RNA binding motif protein 47 | -0.0176077 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0174822 |
| VCL | vinculin | -0.0173764 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0171664 |
| RPS8 | ribosomal protein S8 | -0.0171539 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.01703 |
| CDK13 | cyclin-dependent kinase 13 | -0.0169234 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0168554 |
| SPAG9 | sperm associated antigen 9 | -0.0166562 |
| RPL26 | ribosomal protein L26 | -0.016592 |
| COPA | coatomer protein complex, subunit alpha | -0.0165364 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.0164682 |
| RBM39 | RNA binding motif protein 39 | -0.01643 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0164062 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0161118 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0161081 |
| TUBB | tubulin, beta class I | -0.0159381 |
| TXNRD1 | thioredoxin reductase 1 | -0.0159128 |
| RPS27A | ribosomal protein S27a | -0.015898 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0158726 |
