vinpocetine-1557 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the vinpocetine-1557 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCG4 ATP-binding cassette, sub-family G (WHITE), member 4
AGRP agouti related neuropeptide
AK1 adenylate kinase 1
APH1A APH1A gamma secretase subunit
ATXN7L3B ataxin 7-like 3B
BRE brain and reproductive organ-expressed (TNFRSF1A modulator)
C22ORF24 chromosome 22 open reading frame 24
C22ORF29 chromosome 22 open reading frame 29
CANT1 calcium activated nucleotidase 1
CCR1 chemokine (C-C motif) receptor 1
CLEC11A C-type lectin domain family 11, member A
CLIC4 chloride intracellular channel 4
COPS5 COP9 signalosome subunit 5
CRNKL1 crooked neck pre-mRNA splicing factor 1
CTSB cathepsin B
CTSZ cathepsin Z
DAXX death-domain associated protein
DBF4 DBF4 zinc finger
ERCC4 excision repair cross-complementation group 4
EVL Enah/Vasp-like
FAM149B1 family with sequence similarity 149, member B1
FANCA Fanconi anemia, complementation group A
FAS Fas cell surface death receptor
FKBP9 FK506 binding protein 9, 63 kDa
FOXK2 forkhead box K2
GIMAP5 GTPase, IMAP family member 5
GNB3 guanine nucleotide binding protein (G protein), beta polypeptide 3
GOSR2 golgi SNAP receptor complex member 2
GSAP gamma-secretase activating protein
GSK3A glycogen synthase kinase 3 alpha
H2AFX H2A histone family, member X
HFE hemochromatosis
HIF1AN hypoxia inducible factor 1, alpha subunit inhibitor
HK2 hexokinase 2
HMGA2 high mobility group AT-hook 2
HRH1 histamine receptor H1
IDS iduronate 2-sulfatase
IL27RA interleukin 27 receptor, alpha
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
INPP5E inositol polyphosphate-5-phosphatase, 72 kDa
KAZALD1 Kazal-type serine peptidase inhibitor domain 1
KDM5A lysine (K)-specific demethylase 5A
KLHDC4 kelch domain containing 4
LUZP1 leucine zipper protein 1
MBOAT7 membrane bound O-acyltransferase domain containing 7
MED9 mediator complex subunit 9
METTL13 methyltransferase like 13
MICALL1 MICAL-like 1
MICALL2 MICAL-like 2
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MPZL1 myelin protein zero-like 1
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MXD4 MAX dimerization protein 4
MYO1C myosin IC
NDRG2 NDRG family member 2
NENF neudesin neurotrophic factor
NPRL3 nitrogen permease regulator-like 3 (S. cerevisiae)
NR4A2 nuclear receptor subfamily 4, group A, member 2
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5
PARP16 poly (ADP-ribose) polymerase family, member 16
PCIF1 PDX1 C-terminal inhibiting factor 1
PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor
PELI1 pellino E3 ubiquitin protein ligase 1
PPT2 palmitoyl-protein thioesterase 2
PRDM11 PR domain containing 11
PRPH peripherin
PRRC1 proline-rich coiled-coil 1
PTN pleiotrophin
RAB22A RAB22A, member RAS oncogene family
RANBP3 RAN binding protein 3
RGS10 regulator of G-protein signaling 10
RPS11 ribosomal protein S11
SAMM50 SAMM50 sorting and assembly machinery component
SEC23IP SEC23 interacting protein
SIDT2 SID1 transmembrane family, member 2
SLC17A9 solute carrier family 17 (vesicular nucleotide transporter), member 9
SLC19A1 solute carrier family 19 (folate transporter), member 1
SLC35E3 solute carrier family 35, member E3
SLK STE20-like kinase
SMC5 structural maintenance of chromosomes 5
SPG20 spastic paraplegia 20 (Troyer syndrome)
SPN sialophorin
SPPL2B signal peptide peptidase like 2B
STARD5 StAR-related lipid transfer (START) domain containing 5
TAF12 TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa
TBC1D22A TBC1 domain family, member 22A
TRAIP TRAF interacting protein
TRAPPC12 trafficking protein particle complex 12
TRPM3 transient receptor potential cation channel, subfamily M, member 3
TTC23 tetratricopeptide repeat domain 23
TTC26 tetratricopeptide repeat domain 26
USF2 upstream transcription factor 2, c-fos interacting
VRK3 vaccinia related kinase 3
WNT10B wingless-type MMTV integration site family, member 10B
ZKSCAN4 zinc finger with KRAB and SCAN domains 4
ZMYM2 zinc finger, MYM-type 2
ZNF202 zinc finger protein 202
ZNF771 zinc finger protein 771

decreased expression

Symbol Name
ALS2CL ALS2 C-terminal like
ANKRD40 ankyrin repeat domain 40
ANXA6 annexin A6
ARCN1 archain 1
ARMC7 armadillo repeat containing 7
AZI2 5-azacytidine induced 2
BCORL1 BCL6 corepressor-like 1
BDH1 3-hydroxybutyrate dehydrogenase, type 1
CALCOCO1 calcium binding and coiled-coil domain 1
CASP8AP2 caspase 8 associated protein 2
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CD302 CD302 molecule
CD69 CD69 molecule
CEP85 centrosomal protein 85kDa
COMMD10 COMM domain containing 10
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1
DAZAP1 DAZ associated protein 1
DCLRE1A DNA cross-link repair 1A
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3
ELP5 elongator acetyltransferase complex subunit 5
ERAL1 Era-like 12S mitochondrial rRNA chaperone 1
FAM46A family with sequence similarity 46, member A
FBXO5 F-box protein 5
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32)
GBAP1 glucosidase, beta, acid pseudogene 1
GBP2 guanylate binding protein 2, interferon-inducible
GPATCH2 G patch domain containing 2
GSTCD glutathione S-transferase, C-terminal domain containing
GUF1 GUF1 GTPase homolog (S. cerevisiae)
HACD2 3-hydroxyacyl-CoA dehydratase 2
HIST2H2BE histone cluster 2, H2be
HS1BP3 HCLS1 binding protein 3
HSPA4L heat shock 70kDa protein 4-like
IFITM3 interferon induced transmembrane protein 3
IL4R interleukin 4 receptor
KATNBL1 katanin p80 subunit B-like 1
KIAA0753 KIAA0753
KIF1BP KIF1 binding protein
KRT38 keratin 38, type I
LACTB2 lactamase, beta 2
LZTR1 leucine-zipper-like transcription regulator 1
MAGOHB mago-nashi homolog B (Drosophila)
MAPKBP1 mitogen-activated protein kinase binding protein 1
MAST3 microtubule associated serine/threonine kinase 3
MATK megakaryocyte-associated tyrosine kinase
MBIP MAP3K12 binding inhibitory protein 1
MLC1 megalencephalic leukoencephalopathy with subcortical cysts 1
MNDA myeloid cell nuclear differentiation antigen
MOSPD3 motile sperm domain containing 3
MT1HL1 metallothionein 1H-like 1
MYO19 myosin XIX
MYO5C myosin VC
NAA16 N(alpha)-acetyltransferase 16, NatA auxiliary subunit
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
OGFRL1 opioid growth factor receptor-like 1
OR1D2 olfactory receptor, family 1, subfamily D, member 2
P2RY2 purinergic receptor P2Y, G-protein coupled, 2
PADI1 peptidyl arginine deiminase, type I
PALB2 partner and localizer of BRCA2
PHLDA3 pleckstrin homology-like domain, family A, member 3
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1
PISD phosphatidylserine decarboxylase
PNPLA6 patatin-like phospholipase domain containing 6
POLI polymerase (DNA directed) iota
PSKH1 protein serine kinase H1
RAB8B RAB8B, member RAS oncogene family
RANBP6 RAN binding protein 6
RFPL3 ret finger protein-like 3
RNASE6 ribonuclease, RNase A family, k6
RNF103 ring finger protein 103
RNF170 ring finger protein 170
RPGR retinitis pigmentosa GTPase regulator
RPL23AP32 ribosomal protein L23a pseudogene 32
RPRD2 regulation of nuclear pre-mRNA domain containing 2
RSBN1 round spermatid basic protein 1
RTN3 reticulon 3
SATB1 SATB homeobox 1
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SLN sarcolipin
SSSCA1 Sjogren syndrome/scleroderma autoantigen 1
STARD3 StAR-related lipid transfer (START) domain containing 3
SYT13 synaptotagmin XIII
TAC3 tachykinin 3
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TIAM2 T-cell lymphoma invasion and metastasis 2
TJP2 tight junction protein 2
TMEM186 transmembrane protein 186
TRAPPC11 trafficking protein particle complex 11
TRIM45 tripartite motif containing 45
TSEN34 TSEN34 tRNA splicing endonuclease subunit
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
WDR19 WD repeat domain 19
WDR82 WD repeat domain 82
ZNF282 zinc finger protein 282
ZNF426 zinc finger protein 426
ZNF606 zinc finger protein 606
ZNF768 zinc finger protein 768