vinpocetine-3174 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the vinpocetine-3174 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAM19 ADAM metallopeptidase domain 19
ADGB androglobin
AFF1 AF4/FMR2 family, member 1
AKAP8L A kinase (PRKA) anchor protein 8-like
AKR1C4 aldo-keto reductase family 1, member C4
ARHGDIG Rho GDP dissociation inhibitor (GDI) gamma
ATP8A2 ATPase, aminophospholipid transporter, class I, type 8A, member 2
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
ATPAF2 ATP synthase mitochondrial F1 complex assembly factor 2
B4GALT6 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6
C1ORF61 chromosome 1 open reading frame 61
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CALCRL calcitonin receptor-like
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta
CCDC57 coiled-coil domain containing 57
CDC14B cell division cycle 14B
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CDCP1 CUB domain containing protein 1
CFLAR CASP8 and FADD-like apoptosis regulator
CGA glycoprotein hormones, alpha polypeptide
CLTA clathrin, light chain A
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
DGCR6L DiGeorge syndrome critical region gene 6-like
DKKL1 dickkopf-like 1
DMP1 dentin matrix acidic phosphoprotein 1
ECE1 endothelin converting enzyme 1
EHD1 EH-domain containing 1
ELOVL5 ELOVL fatty acid elongase 5
EXOSC1 exosome component 1
F5 coagulation factor V (proaccelerin, labile factor)
FASTKD2 FAST kinase domains 2
FH fumarate hydratase
FKBP10 FK506 binding protein 10, 65 kDa
GIMAP5 GTPase, IMAP family member 5
GJB3 gap junction protein, beta 3, 31kDa
GLUD2 glutamate dehydrogenase 2
GRM8 glutamate receptor, metabotropic 8
GSDMB gasdermin B
GSN gelsolin
HAMP hepcidin antimicrobial peptide
HOXA10 homeobox A10
IGHD immunoglobulin heavy constant delta
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
IMPG2 interphotoreceptor matrix proteoglycan 2
KIF25 kinesin family member 25
KRT15 keratin 15, type I
LARP7 La ribonucleoprotein domain family, member 7
LCT lactase
LDB3 LIM domain binding 3
LMF2 lipase maturation factor 2
MAPK7 mitogen-activated protein kinase 7
MEF2C myocyte enhancer factor 2C
MEP1B meprin A, beta
MIA2 melanoma inhibitory activity 2
MMP3 matrix metallopeptidase 3
MRPL41 mitochondrial ribosomal protein L41
MRPS18C mitochondrial ribosomal protein S18C
MSR1 macrophage scavenger receptor 1
MST1 macrophage stimulating 1
MYOT myotilin
NEURL1 neuralized E3 ubiquitin protein ligase 1
NT5M 5',3'-nucleotidase, mitochondrial
NUP88 nucleoporin 88kDa
NUPR1 nuclear protein, transcriptional regulator, 1
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit
PRM1 protamine 1
PRSS21 protease, serine, 21 (testisin)
PSD4 pleckstrin and Sec7 domain containing 4
PTGIS prostaglandin I2 (prostacyclin) synthase
PTPN12 protein tyrosine phosphatase, non-receptor type 12
RPL35A ribosomal protein L35a
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
SFI1 Sfi1 homolog, spindle assembly associated (yeast)
SIRT5 sirtuin 5
SLC16A5 solute carrier family 16 (monocarboxylate transporter), member 5
SNAP25 synaptosomal-associated protein, 25kDa
SNTA1 syntrophin, alpha 1
SPIB Spi-B transcription factor (Spi-1/PU.1 related)
SPRR1A small proline-rich protein 1A
STATH statherin
SULT2A1 sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1
SYMPK symplekin
TDRKH tudor and KH domain containing
TECTA tectorin alpha
TEX40 testis expressed 40
TRIP11 thyroid hormone receptor interactor 11
TRPM8 transient receptor potential cation channel, subfamily M, member 8
TTLL5 tubulin tyrosine ligase-like family member 5
TTLL7 tubulin tyrosine ligase-like family member 7
UBE2D1 ubiquitin-conjugating enzyme E2D 1
VPS53 vacuolar protein sorting 53 homolog (S. cerevisiae)
VRTN vertebrae development associated
VWA5A von Willebrand factor A domain containing 5A
WDR4 WD repeat domain 4
WDR55 WD repeat domain 55
ZIC3 Zic family member 3
ZNF506 zinc finger protein 506
ZNF783 zinc finger family member 783

decreased expression

Symbol Name
ABHD17B abhydrolase domain containing 17B
ABHD4 abhydrolase domain containing 4
ADCY7 adenylate cyclase 7
ADGRG2 adhesion G protein-coupled receptor G2
AFAP1 actin filament associated protein 1
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
ARHGAP5 Rho GTPase activating protein 5
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
ARRB2 arrestin, beta 2
ASPHD1 aspartate beta-hydroxylase domain containing 1
C11ORF80 chromosome 11 open reading frame 80
C21ORF91 chromosome 21 open reading frame 91
C2ORF27A chromosome 2 open reading frame 27A
CAMKV CaM kinase-like vesicle-associated
CCBL1 cysteine conjugate-beta lyase, cytoplasmic
CD53 CD53 molecule
CEP162 centrosomal protein 162kDa
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
CIDEC cell death-inducing DFFA-like effector c
CLCN5 chloride channel, voltage-sensitive 5
CLSPN claspin
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
EIF5A2 eukaryotic translation initiation factor 5A2
ELAVL3 ELAV like neuron-specific RNA binding protein 3
ERMAP erythroblast membrane-associated protein (Scianna blood group)
EXOC6B exocyst complex component 6B
FAAH fatty acid amide hydrolase
FBXW12 F-box and WD repeat domain containing 12
FGGY FGGY carbohydrate kinase domain containing
FLCN folliculin
FMO4 flavin containing monooxygenase 4
FUZ fuzzy planar cell polarity protein
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GPX1 glutathione peroxidase 1
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HIST1H1B histone cluster 1, H1b
HIST1H2AJ histone cluster 1, H2aj
HIST1H2AL histone cluster 1, H2al
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HOXA5 homeobox A5
HOXC5 homeobox C5
IFI35 interferon-induced protein 35
IFT140 intraflagellar transport 140
IFT88 intraflagellar transport 88
IL15RA interleukin 15 receptor, alpha
IL4R interleukin 4 receptor
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KDM8 lysine (K)-specific demethylase 8
KIAA1456 KIAA1456
KIF13A kinesin family member 13A
KRT83 keratin 83, type II
LDHB lactate dehydrogenase B
LHX1 LIM homeobox 1
LLPH LLP homolog, long-term synaptic facilitation (Aplysia)
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
LYZ lysozyme
MEIS2 Meis homeobox 2
MMP15 matrix metallopeptidase 15 (membrane-inserted)
MPO myeloperoxidase
NIPAL2 NIPA-like domain containing 2
NT5E 5'-nucleotidase, ecto (CD73)
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18
ONECUT2 one cut homeobox 2
PCDHA6 protocadherin alpha 6
PLEKHO2 pleckstrin homology domain containing, family O member 2
PODXL2 podocalyxin-like 2
PPP2R3B protein phosphatase 2, regulatory subunit B'', beta
RAB5B RAB5B, member RAS oncogene family
RELN reelin
REM1 RAS (RAD and GEM)-like GTP-binding 1
RFTN1 raftlin, lipid raft linker 1
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
SCGB2A2 secretoglobin, family 2A, member 2
SEC61A2 Sec61 alpha 2 subunit (S. cerevisiae)
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SLC12A8 solute carrier family 12, member 8
SLC16A10 solute carrier family 16 (aromatic amino acid transporter), member 10
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SOX3 SRY (sex determining region Y)-box 3
THBS3 thrombospondin 3
TMEM62 transmembrane protein 62
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein
UBXN6 UBX domain protein 6
ULBP2 UL16 binding protein 2
UPK3B uroplakin 3B
USP19 ubiquitin specific peptidase 19
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
VASH2 vasohibin 2
WDR76 WD repeat domain 76
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
ZNF324 zinc finger protein 324
ZNF34 zinc finger protein 34
ZNF428 zinc finger protein 428
ZNF552 zinc finger protein 552