vital Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

160 genes co-occuring with the biological term vital in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1
ACTB actin, beta
AKR1C3 aldo-keto reductase family 1, member C3
ANKRD18A ankyrin repeat domain 18A
APPL1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
ARFGEF1 ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited)
ATM ATM serine/threonine kinase
AVP arginine vasopressin
BCL2L11 BCL2-like 11 (apoptosis facilitator)
BIRC5 baculoviral IAP repeat containing 5
BMI1 BMI1 proto-oncogene, polycomb ring finger
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase)
BRIP1 BRCA1 interacting protein C-terminal helicase 1
BTNL2 butyrophilin-like 2
C2 complement component 2
CAT catalase
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)
CCL3 chemokine (C-C motif) ligand 3
CDK11B cyclin-dependent kinase 11B
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN2AIP CDKN2A interacting protein
CDSN corneodesmosin
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CHMP4B charged multivesicular body protein 4B
CISH cytokine inducible SH2-containing protein
CLIC2 chloride intracellular channel 2
CLSPN claspin
COL18A1 collagen, type XVIII, alpha 1
COPS5 COP9 signalosome subunit 5
CPSF6 cleavage and polyadenylation specific factor 6, 68kDa
CRYAA crystallin, alpha A
CRYAB crystallin, alpha B
CTGF connective tissue growth factor
CUL4A cullin 4A
CXADR coxsackie virus and adenovirus receptor
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL8 chemokine (C-X-C motif) ligand 8
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
DMBT1 deleted in malignant brain tumors 1
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12
DNAJC24 DnaJ (Hsp40) homolog, subfamily C, member 24
DPP10 dipeptidyl-peptidase 10 (non-functional)
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
EP300 E1A binding protein p300
EPHA2 EPH receptor A2
EPHB4 EPH receptor B4
EPHX2 epoxide hydrolase 2, cytoplasmic
ERBB4 erb-b2 receptor tyrosine kinase 4
ERCC2 excision repair cross-complementation group 2
FAM3B family with sequence similarity 3, member B
FLII flightless I homolog (Drosophila)
FLT1 fms-related tyrosine kinase 1
FOXO1 forkhead box O1
FOXP3 forkhead box P3
FZD4 frizzled class receptor 4
GCK glucokinase (hexokinase 4)
GGA2 golgi-associated, gamma adaptin ear containing, ARF binding protein 2
GJA8 gap junction protein, alpha 8, 50kDa
GJD2 gap junction protein, delta 2, 36kDa
GPSM2 G-protein signaling modulator 2
GSK3B glycogen synthase kinase 3 beta
GSTM1 glutathione S-transferase mu 1
GSTT1 glutathione S-transferase theta 1
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
HAS2 hyaluronan synthase 2
HBEGF heparin-binding EGF-like growth factor
HDAC1 histone deacetylase 1
HDAC2 histone deacetylase 2
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HMGB1 high mobility group box 1
HMOX1 heme oxygenase 1
HOTAIR HOX transcript antisense RNA
HTT huntingtin
ICOS inducible T-cell co-stimulator
IGF1 insulin-like growth factor 1 (somatomedin C)
IGFBP3 insulin-like growth factor binding protein 3
IGHE immunoglobulin heavy constant epsilon
IL2 interleukin 2
INSC inscuteable homolog (Drosophila)
IRS2 insulin receptor substrate 2
ITSN2 intersectin 2
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KLF1 Kruppel-like factor 1 (erythroid)
MAGEA1 melanoma antigen family A1
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MFI2 antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5
MIR146A microRNA 146a
MIR200B microRNA 200b
MIR96 microRNA 96
MKI67 marker of proliferation Ki-67
MLH1 mutL homolog 1
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MMP2 matrix metallopeptidase 2
MMP9 matrix metallopeptidase 9
MSH2 mutS homolog 2
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MUTYH mutY homolog
MYC v-myc avian myelocytomatosis viral oncogene homolog
NBN nibrin
NDRG1 N-myc downstream regulated 1
NF2 neurofibromin 2 (merlin)
NPPB natriuretic peptide B
NR5A2 nuclear receptor subfamily 5, group A, member 2
PDGFB platelet-derived growth factor beta polypeptide
PDGFRB platelet-derived growth factor receptor, beta polypeptide
PELP1 proline, glutamate and leucine rich protein 1
PHB prohibitin
PLEK pleckstrin
POSTN periostin, osteoblast specific factor
PPARD peroxisome proliferator-activated receptor delta
PPARG peroxisome proliferator-activated receptor gamma
PRELID1 PRELI domain containing 1
PTEN phosphatase and tensin homolog
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PXN paxillin
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RAD9A RAD9 homolog A (S. pombe)
RAP1A RAP1A, member of RAS oncogene family
RASD2 RASD family, member 2
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RASSF2 Ras association (RalGDS/AF-6) domain family member 2
RECQL RecQ helicase-like
RHOA ras homolog family member A
RUNX1 runt-related transcription factor 1
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
SFTPD surfactant protein D
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SIRT1 sirtuin 1
SLC15A2 solute carrier family 15 (oligopeptide transporter), member 2
SLC23A2 solute carrier family 23 (ascorbic acid transporter), member 2
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SOD1 superoxide dismutase 1, soluble
SOD2 superoxide dismutase 2, mitochondrial
SOD3 superoxide dismutase 3, extracellular
ST14 suppression of tumorigenicity 14 (colon carcinoma)
STX4 syntaxin 4
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TCP1 t-complex 1
TEAD4 TEA domain family member 4
TERT telomerase reverse transcriptase
TGFB1 transforming growth factor, beta 1
TLR2 toll-like receptor 2
TLR3 toll-like receptor 3
TLR6 toll-like receptor 6
TNFRSF4 tumor necrosis factor receptor superfamily, member 4
TNFRSF6B tumor necrosis factor receptor superfamily, member 6b, decoy
TP53 tumor protein p53
TP53BP1 tumor protein p53 binding protein 1
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TRIM5 tripartite motif containing 5
TRPM6 transient receptor potential cation channel, subfamily M, member 6
TRPM7 transient receptor potential cation channel, subfamily M, member 7
TWIST1 twist family bHLH transcription factor 1
UTS2 urotensin 2
VEGFA vascular endothelial growth factor A
WNT3A wingless-type MMTV integration site family, member 3A
WT1 Wilms tumor 1