vitexin-2810 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the vitexin-2810 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ALCAM activated leukocyte cell adhesion molecule
AMPD3 adenosine monophosphate deaminase 3
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle)
APAF1 apoptotic peptidase activating factor 1
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ARL3 ADP-ribosylation factor-like 3
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
BCL3 B-cell CLL/lymphoma 3
C1ORF95 chromosome 1 open reading frame 95
C3AR1 complement component 3a receptor 1
CABIN1 calcineurin binding protein 1
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2
CCDC40 coiled-coil domain containing 40
CCNO cyclin O
CD34 CD34 molecule
CTSF cathepsin F
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DGCR2 DiGeorge syndrome critical region gene 2
DMTN dematin actin binding protein
DNAH17 dynein, axonemal, heavy chain 17
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DUSP13 dual specificity phosphatase 13
EDIL3 EGF-like repeats and discoidin I-like domains 3
ERN2 endoplasmic reticulum to nucleus signaling 2
FAM46C family with sequence similarity 46, member C
FUT9 fucosyltransferase 9 (alpha (1,3) fucosyltransferase)
GLRA1 glycine receptor, alpha 1
GNAT2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2
GPR21 G protein-coupled receptor 21
GSN gelsolin
GULP1 GULP, engulfment adaptor PTB domain containing 1
HIST1H4E histone cluster 1, H4e
HOXC4 homeobox C4
HS3ST2 heparan sulfate (glucosamine) 3-O-sulfotransferase 2
HS6ST1 heparan sulfate 6-O-sulfotransferase 1
JAM3 junctional adhesion molecule 3
KAT6A K(lysine) acetyltransferase 6A
KAZALD1 Kazal-type serine peptidase inhibitor domain 1
KCNJ15 potassium channel, inwardly rectifying subfamily J, member 15
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KCNQ3 potassium channel, voltage gated KQT-like subfamily Q, member 3
KIAA1109 KIAA1109
KREMEN2 kringle containing transmembrane protein 2
LAMP1 lysosomal-associated membrane protein 1
LAT2 linker for activation of T cells family, member 2
LOC647070 uncharacterized LOC647070
LRRC8B leucine rich repeat containing 8 family, member B
LYZL6 lysozyme-like 6
MASP2 mannan-binding lectin serine peptidase 2
MMP11 matrix metallopeptidase 11
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MVP major vault protein
NIPSNAP3B nipsnap homolog 3B (C. elegans)
NKX3-1 NK3 homeobox 1
NPHP1 nephronophthisis 1 (juvenile)
NR2F1 nuclear receptor subfamily 2, group F, member 1
NR4A1 nuclear receptor subfamily 4, group A, member 1
NTF3 neurotrophin 3
NXPH4 neurexophilin 4
PAPPA pregnancy-associated plasma protein A, pappalysin 1
PEX3 peroxisomal biogenesis factor 3
PLAT plasminogen activator, tissue
PRDM2 PR domain containing 2, with ZNF domain
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit
PRSS53 protease, serine, 53
PTRF polymerase I and transcript release factor
RAB11FIP2 RAB11 family interacting protein 2 (class I)
RAB33A RAB33A, member RAS oncogene family
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RBM3 RNA binding motif (RNP1, RRM) protein 3
RETN resistin
RPL35A ribosomal protein L35a
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
S100A9 S100 calcium binding protein A9
SCN1B sodium channel, voltage gated, type I beta subunit
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
SERHL2 serine hydrolase-like 2
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SSX3 synovial sarcoma, X breakpoint 3
STARD3 StAR-related lipid transfer (START) domain containing 3
TCF20 transcription factor 20 (AR1)
TIMM8A translocase of inner mitochondrial membrane 8 homolog A (yeast)
TMEM144 transmembrane protein 144
TMEM63A transmembrane protein 63A
TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
TREM2 triggering receptor expressed on myeloid cells 2
TRIO trio Rho guanine nucleotide exchange factor
TSC22D4 TSC22 domain family, member 4
UTRN utrophin
VAC14 Vac14 homolog (S. cerevisiae)
VCL vinculin
VPS13B vacuolar protein sorting 13 homolog B (yeast)
VPS9D1 VPS9 domain containing 1
WDR62 WD repeat domain 62
ZNF528 zinc finger protein 528
ZNF589 zinc finger protein 589
ZNF76 zinc finger protein 76

decreased expression

Symbol Name
ABCA12 ATP-binding cassette, sub-family A (ABC1), member 12
ALPK1 alpha-kinase 1
ANKRD36 ankyrin repeat domain 36
ARSB arylsulfatase B
C11ORF30 chromosome 11 open reading frame 30
C14ORF93 chromosome 14 open reading frame 93
C19ORF73 chromosome 19 open reading frame 73
CCDC132 coiled-coil domain containing 132
CCNT1 cyclin T1
CENPO centromere protein O
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CLDN15 claudin 15
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
CWC25 CWC25 spliceosome-associated protein homolog (S. cerevisiae)
DBF4B DBF4 zinc finger B
DBNDD1 dysbindin (dystrobrevin binding protein 1) domain containing 1
DGAT1 diacylglycerol O-acyltransferase 1
EPHX2 epoxide hydrolase 2, cytoplasmic
ERCC6 excision repair cross-complementation group 6
ETAA1 Ewing tumor-associated antigen 1
EYA2 EYA transcriptional coactivator and phosphatase 2
FAM160B2 family with sequence similarity 160, member B2
FAM169A family with sequence similarity 169, member A
FAM188A family with sequence similarity 188, member A
FAM53B family with sequence similarity 53, member B
FHOD1 formin homology 2 domain containing 1
FSCN1 fascin actin-bundling protein 1
FSTL3 follistatin-like 3 (secreted glycoprotein)
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GAMT guanidinoacetate N-methyltransferase
GBAS glioblastoma amplified sequence
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
HECTD3 HECT domain containing E3 ubiquitin protein ligase 3
HIST1H1D histone cluster 1, H1d
HOXC11 homeobox C11
IFNAR1 interferon (alpha, beta and omega) receptor 1
INF2 inverted formin, FH2 and WH2 domain containing
IRF7 interferon regulatory factor 7
ITPKB inositol-trisphosphate 3-kinase B
KCNK15 potassium channel, two pore domain subfamily K, member 15
KLC2 kinesin light chain 2
KLF11 Kruppel-like factor 11
KPTN kaptin (actin binding protein)
LAMB2 laminin, beta 2 (laminin S)
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase
LRRC49 leucine rich repeat containing 49
LZTR1 leucine-zipper-like transcription regulator 1
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MCOLN3 mucolipin 3
MED24 mediator complex subunit 24
MMP15 matrix metallopeptidase 15 (membrane-inserted)
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MRPL2 mitochondrial ribosomal protein L2
MTHFS 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase)
MUL1 mitochondrial E3 ubiquitin protein ligase 1
MYL12A myosin, light chain 12A, regulatory, non-sarcomeric
NECAB3 N-terminal EF-hand calcium binding protein 3
NPY1R neuropeptide Y receptor Y1
PADI2 peptidyl arginine deiminase, type II
PAQR6 progestin and adipoQ receptor family member VI
PCDHA6 protocadherin alpha 6
PEX26 peroxisomal biogenesis factor 26
PGAP1 post-GPI attachment to proteins 1
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q
PIGZ phosphatidylinositol glycan anchor biosynthesis, class Z
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PLA2G10 phospholipase A2, group X
PLCG1 phospholipase C, gamma 1
PLD2 phospholipase D2
PMCH pro-melanin-concentrating hormone
PPT2 palmitoyl-protein thioesterase 2
PRPH peripherin
PTPRE protein tyrosine phosphatase, receptor type, E
RPH3AL rabphilin 3A-like (without C2 domains)
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4
SCAI suppressor of cancer cell invasion
SCAMP4 secretory carrier membrane protein 4
SEC61A2 Sec61 alpha 2 subunit (S. cerevisiae)
SFT2D2 SFT2 domain containing 2
SHB Src homology 2 domain containing adaptor protein B
SIGIRR single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
SMA4 glucuronidase, beta pseudogene
SMIM14 small integral membrane protein 14
SPINK4 serine peptidase inhibitor, Kazal type 4
TCTA T-cell leukemia translocation altered
TEP1 telomerase-associated protein 1
TGFBRAP1 transforming growth factor, beta receptor associated protein 1
TMEM104 transmembrane protein 104
TMEM62 transmembrane protein 62
TNS2 tensin 2
TRAIP TRAF interacting protein
TTBK2 tau tubulin kinase 2
UGGT2 UDP-glucose glycoprotein glucosyltransferase 2
UNC119 unc-119 homolog (C. elegans)
WDR91 WD repeat domain 91
ZC3H12A zinc finger CCCH-type containing 12A
ZCWPW1 zinc finger, CW type with PWWP domain 1
ZNF639 zinc finger protein 639
ZNF862 zinc finger protein 862