vitiligo Gene Set

Dataset DISEASES Experimental Gene-Disease Association Evidence Scores
Category disease or phenotype associations
Type disease
Description A disorder consisting of areas of macular depigmentation, commonly on extensor aspects of extremities, on the face or neck, and in skin folds. Age of onset is often in young adulthood and the condition tends to progress gradually with lesions enlarging and extending until a quiescent state is reached. (Experimental Factor Ontology, EFO_0004208)
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Genes

60 genes associated with the disease vitiligo in GWAS datasets from the DISEASES Experimental Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
SLC44A4 solute carrier family 44, member 4 2.18152
HLA-C major histocompatibility complex, class I, C 1.84115
HLA-A major histocompatibility complex, class I, A 1.43901
TYR tyrosinase 1.27521
RNASET2 ribonuclease T2 1.17894
C1QTNF6 C1q and tumor necrosis factor related protein 6 1.14929
FAP fibroblast activation protein, alpha 1.04495
RERE arginine-glutamic acid dipeptide (RE) repeats 1.03485
FANCA Fanconi anemia, complementation group A 0.945428
LPP LIM domain containing preferred translocation partner in lipoma 0.817078
NOTCH4 notch 4 0.790827
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 0.724323
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 0.724323
TNXB tenascin XB 0.69843
ATF6B activating transcription factor 6 beta 0.682635
FKBPL FK506 binding protein like 0.670996
ADPRH ADP-ribosylarginine hydrolase 0.670996
AGPAT1 1-acylglycerol-3-phosphate O-acyltransferase 1 0.670996
RNF5 ring finger protein 5, E3 ubiquitin protein ligase 0.661797
DDX39B DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B 0.661797
ZC3H7B zinc finger CCCH-type containing 7B 0.647573
UBASH3A ubiquitin associated and SH3 domain containing A 0.63207
MICA MHC class I polypeptide-related sequence A 0.602429
SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2 0.602429
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6 0.602429
GTF2H4 general transcription factor IIH, polypeptide 4, 52kDa 0.602429
MUC21 mucin 21, cell surface associated 0.58494
IL2RA interleukin 2 receptor, alpha 0.58494
ATAT1 alpha tubulin acetyltransferase 1 0.561725
DPCR1 diffuse panbronchiolitis critical region 1 0.561725
POU5F1 POU class 5 homeobox 1 0.552621
C6ORF15 chromosome 6 open reading frame 15 0.537125
HLA-E major histocompatibility complex, class I, E 0.5306
TRIM31 tripartite motif containing 31 0.52461
TRIM15 tripartite motif containing 15 0.52461
RPP21 ribonuclease P/MRP 21kDa subunit 0.52461
TG thyroglobulin 0.486425
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) 0.464771
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2 0.464771
IER3 immediate early response 3 0.449873
CASP7 caspase 7, apoptosis-related cysteine peptidase 0.449873
HERC2 HECT and RLD domain containing E3 ubiquitin protein ligase 2 0.449873
NEU1 sialidase 1 (lysosomal sialidase) 0.449873
HLA-G major histocompatibility complex, class I, G 0.449873
TRIM26 tripartite motif containing 26 0.449873
TICAM1 toll-like receptor adaptor molecule 1 0.408752
SMOC2 SPARC related modular calcium binding 2 0.408752
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid) 0.403461
IKZF4 IKAROS family zinc finger 4 (Eos) 0.368757
MYH15 myosin, heavy chain 15 0.345945
RAB5B RAB5B, member RAS oncogene family 0.285417
ZMIZ1 zinc finger, MIZ-type containing 1 0.274608
RETNLB resistin like beta 0.256228
HUNK hormonally up-regulated Neu-associated kinase 0.197766
ZNF385B zinc finger protein 385B 0.197766
SUOX sulfite oxidase 0.15771
FOXP1 forkhead box P1 0.126165
CCR6 chemokine (C-C motif) receptor 6 0.126165
SH2B3 SH2B adaptor protein 3 0.064973
ATXN2 ataxin 2 0.035343