vitiligo Gene Set

Dataset GAD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description A disorder consisting of areas of macular depigmentation, commonly on extensor aspects of extremities, on the face or neck, and in skin folds. Age of onset is often in young adulthood and the condition tends to progress gradually with lesions enlarging and extending until a quiescent state is reached. (Experimental Factor Ontology, EFO_0004208)
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Genes

72 genes associated with the disease vitiligo in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

Symbol Name
ACE angiotensin I converting enzyme
AIRE autoimmune regulator
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
BTNL2 butyrophilin-like 2
C12ORF10 chromosome 12 open reading frame 10
C1QTNF6 C1q and tumor necrosis factor related protein 6
CAT catalase
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CCR6 chemokine (C-C motif) receptor 6
CD4 CD4 molecule
CLEC11A C-type lectin domain family 11, member A
COMT catechol-O-methyltransferase
CORO2A coronin, actin binding protein, 2A
CTLA4 cytotoxic T-lymphocyte-associated protein 4
DDR1 discoidin domain receptor tyrosine kinase 1
EDN1 endothelin 1
ESR1 estrogen receptor 1
FAS Fas cell surface death receptor
FASLG Fas ligand (TNF superfamily, member 6)
FBXO11 F-box protein 11
FGFR1OP FGFR1 oncogene partner
FOXD3 forkhead box D3
FOXP1 forkhead box P1
FOXP3 forkhead box P3
GSTM1 glutathione S-transferase mu 1
GSTP1 glutathione S-transferase pi 1
GSTT1 glutathione S-transferase theta 1
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
HCG9 HLA complex group 9 (non-protein coding)
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HLA-A major histocompatibility complex, class I, A
HLA-B major histocompatibility complex, class I, B
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HUNK hormonally up-regulated Neu-associated kinase
ICA1 islet cell autoantigen 1, 69kDa
IFNG interferon, gamma
IL10 interleukin 10
IL1RN interleukin 1 receptor antagonist
IL2RA interleukin 2 receptor, alpha
IL4 interleukin 4
KCNK12 potassium channel, two pore domain subfamily K, member 12
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KITLG KIT ligand
LPP LIM domain containing preferred translocation partner in lipoma
MBL2 mannose-binding lectin (protein C) 2, soluble
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MPO myeloperoxidase
NFE2L2 nuclear factor, erythroid 2-like 2
NLRP1 NLR family, pyrin domain containing 1
NUDT6 nudix (nucleoside diphosphate linked moiety X)-type motif 6
PDE10A phosphodiesterase 10A
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
RAB5B RAB5B, member RAS oncogene family
RERE arginine-glutamic acid dipeptide (RE) repeats
RNASET2 ribonuclease T2
SLC44A4 solute carrier family 44, member 4
SMOC2 SPARC related modular calcium binding 2
STAT4 signal transducer and activator of transcription 4
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TNF tumor necrosis factor
TSLP thymic stromal lymphopoietin
TXNDC5 thioredoxin domain containing 5 (endoplasmic reticulum)
TYR tyrosinase
UBASH3A ubiquitin associated and SH3 domain containing A
UVRAG UV radiation resistance associated
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
XBP1 X-box binding protein 1
ZMIZ1 zinc finger, MIZ-type containing 1