vitiligo Gene Set

Dataset GWASdb SNP-Disease Associations
Category disease or phenotype associations
Type disease
Description A disorder consisting of areas of macular depigmentation, commonly on extensor aspects of extremities, on the face or neck, and in skin folds. Age of onset is often in young adulthood and the condition tends to progress gradually with lesions enlarging and extending until a quiescent state is reached. (Experimental Factor Ontology, EFO_0004208)
External Link http://jjwanglab.org/gwasdb/gwasdb2/gwasdb2/go_trait/DOID:12306
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Genes

68 genes associated with the disease vitiligo in GWAS and other genetic association datasets from the GWASdb SNP-Disease Associations dataset.

Symbol Name Standardized Value
SLC44A4 solute carrier family 44, member 4 2.54172
BTNL2 butyrophilin-like 2 2.15851
LPP LIM domain containing preferred translocation partner in lipoma 1.99203
TYR tyrosinase 1.94711
ATXN2 ataxin 2 1.93435
C1QTNF6 C1q and tumor necrosis factor related protein 6 1.89043
RNASET2 ribonuclease T2 1.8787
RERE arginine-glutamic acid dipeptide (RE) repeats 1.79589
IKZF4 IKAROS family zinc finger 4 (Eos) 1.76581
IL2RA interleukin 2 receptor, alpha 1.75539
FANCA Fanconi anemia, complementation group A 1.7256
RPGRIP1L RPGRIP1-like 1.70502
UBASH3A ubiquitin associated and SH3 domain containing A 1.65232
NOTCH4 notch 4 1.61856
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 1.56907
TNXB tenascin XB 1.55919
AGPAT1 1-acylglycerol-3-phosphate O-acyltransferase 1 1.54032
EGFL8 EGF-like-domain, multiple 8 1.53276
DDX39B DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B 1.5322
RNF5 ring finger protein 5, E3 ubiquitin protein ligase 1.53099
SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2 1.48714
GTF2H4 general transcription factor IIH, polypeptide 4, 52kDa 1.48409
CCHCR1 coiled-coil alpha-helical rod protein 1 1.48345
ATAT1 alpha tubulin acetyltransferase 1 1.45389
DPCR1 diffuse panbronchiolitis critical region 1 1.45162
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) 1.45047
POU5F1 POU class 5 homeobox 1 1.44045
HCG22 HLA complex group 22 1.43513
PSORS1C3 psoriasis susceptibility 1 candidate 3 (non-protein coding) 1.42693
TRIM15 tripartite motif containing 15 1.41484
TRIM31 tripartite motif containing 31 1.41352
TG thyroglobulin 1.39396
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2 1.37327
CASP7 caspase 7, apoptosis-related cysteine peptidase 1.35834
HERC2 HECT and RLD domain containing E3 ubiquitin protein ligase 2 1.35834
TRIM26 tripartite motif containing 26 1.35516
NEU1 sialidase 1 (lysosomal sialidase) 1.35481
FOXP1 forkhead box P1 1.3491
SMOC2 SPARC related modular calcium binding 2 1.32087
TICAM1 toll-like receptor adaptor molecule 1 1.32087
APOE apolipoprotein E 1.29348
ZMIZ1 zinc finger, MIZ-type containing 1 1.21019
NXPH1 neurexophilin 1 1.11647
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1 1.10764
NEK6 NIMA-related kinase 6 1.07364
SH2B3 SH2B adaptor protein 3 1.0725
ICA1 islet cell autoantigen 1, 69kDa 1.05742
TOMM40 translocase of outer mitochondrial membrane 40 homolog (yeast) 1.03835
UBE2E2 ubiquitin-conjugating enzyme E2E 2 0.974175
CNTN4 contactin 4 0.912226
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator 0.902199
CIB4 calcium and integrin binding family member 4 0.867508
ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 0.856323
SRBD1 S1 RNA binding domain 1 0.838994
DOK6 docking protein 6 0.82192
PHLDB2 pleckstrin homology-like domain, family B, member 2 0.782562
GABRB1 gamma-aminobutyric acid (GABA) A receptor, beta 1 0.779539
DSC3 desmocollin 3 0.763797
CLYBL citrate lyase beta like 0.74447
PRH1-PRR4 PRH1-PRR4 readthrough 0.724417
SORCS1 sortilin-related VPS10 domain containing receptor 1 0.716576
DOCK4 dedicator of cytokinesis 4 0.710807
GHSR growth hormone secretagogue receptor 0.691457
CSMD1 CUB and Sushi multiple domains 1 0.679961
FAM69C family with sequence similarity 69, member C 0.677839
NCS1 neuronal calcium sensor 1 0.653298
IFIH1 interferon induced with helicase C domain 1 0.598248
ZNRD1-AS1 ZNRD1 antisense RNA 1 0.586345