vitiligo Gene Set

Dataset GWASdb SNP-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description A hypersensitivity reaction type II disease that causes depigmentation of patches of skin resulting from loss of function or death of melanoctyes. (Human Disease Ontology, DOID_12306)
External Link http://jjwanglab.org/gwasdb/gwasdb2/gwasdb2/go_trait/HP:0001045
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Genes

68 genes associated with the vitiligo phenotype in GWAS datasets from the GWASdb SNP-Phenotype Associations dataset.

Symbol Name Standardized Value
SLC44A4 solute carrier family 44, member 4 2.55044
BTNL2 butyrophilin-like 2 2.11133
LPP LIM domain containing preferred translocation partner in lipoma 1.93967
TYR tyrosinase 1.88591
ATXN2 ataxin 2 1.87101
C1QTNF6 C1q and tumor necrosis factor related protein 6 1.83117
RNASET2 ribonuclease T2 1.81736
RERE arginine-glutamic acid dipeptide (RE) repeats 1.69824
IKZF4 IKAROS family zinc finger 4 (Eos) 1.66286
IL2RA interleukin 2 receptor, alpha 1.65014
FANCA Fanconi anemia, complementation group A 1.61591
RPGRIP1L RPGRIP1-like 1.57861
UBASH3A ubiquitin associated and SH3 domain containing A 1.52467
NOTCH4 notch 4 1.4821
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 1.43178
TNXB tenascin XB 1.42091
AGPAT1 1-acylglycerol-3-phosphate O-acyltransferase 1 1.39317
EGFL8 EGF-like-domain, multiple 8 1.38278
DDX39B DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B 1.38205
RNF5 ring finger protein 5, E3 ubiquitin protein ligase 1.38047
SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2 1.32793
GTF2H4 general transcription factor IIH, polypeptide 4, 52kDa 1.32379
CCHCR1 coiled-coil alpha-helical rod protein 1 1.32286
ATAT1 alpha tubulin acetyltransferase 1 1.28174
DPCR1 diffuse panbronchiolitis critical region 1 1.27871
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) 1.27708
POU5F1 POU class 5 homeobox 1 1.26433
HCG22 HLA complex group 22 1.25819
PSORS1C3 psoriasis susceptibility 1 candidate 3 (non-protein coding) 1.24979
TRIM15 tripartite motif containing 15 1.23829
TRIM31 tripartite motif containing 31 1.23704
TG thyroglobulin 1.21853
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2 1.19958
CASP7 caspase 7, apoptosis-related cysteine peptidase 1.18704
HERC2 HECT and RLD domain containing E3 ubiquitin protein ligase 2 1.18704
TRIM26 tripartite motif containing 26 1.18447
NEU1 sialidase 1 (lysosomal sialidase) 1.18418
FOXP1 forkhead box P1 1.17979
SMOC2 SPARC related modular calcium binding 2 1.15743
TICAM1 toll-like receptor adaptor molecule 1 1.15743
APOE apolipoprotein E 1.13234
ZMIZ1 zinc finger, MIZ-type containing 1 1.05869
NXPH1 neurexophilin 1 0.976371
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1 0.969142
NEK6 NIMA-related kinase 6 0.940934
SH2B3 SH2B adaptor protein 3 0.939894
ICA1 islet cell autoantigen 1, 69kDa 0.926745
TOMM40 translocase of outer mitochondrial membrane 40 homolog (yeast) 0.911279
UBE2E2 ubiquitin-conjugating enzyme E2E 2 0.858001
CNTN4 contactin 4 0.802296
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator 0.793451
CIB4 calcium and integrin binding family member 4 0.760868
ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 0.74997
SRBD1 S1 RNA binding domain 1 0.733655
DOK6 docking protein 6 0.717203
PHLDB2 pleckstrin homology-like domain, family B, member 2 0.679979
GABRB1 gamma-aminobutyric acid (GABA) A receptor, beta 1 0.676917
DSC3 desmocollin 3 0.661549
CLYBL citrate lyase beta like 0.643425
PRH1-PRR4 PRH1-PRR4 readthrough 0.62426
SORCS1 sortilin-related VPS10 domain containing receptor 1 0.617083
DOCK4 dedicator of cytokinesis 4 0.611597
GHSR growth hormone secretagogue receptor 0.593113
CSMD1 CUB and Sushi multiple domains 1 0.582578
FAM69C family with sequence similarity 69, member C 0.580796
NCS1 neuronal calcium sensor 1 0.557335
IFIH1 interferon induced with helicase C domain 1 0.508244
ZNRD1-AS1 ZNRD1 antisense RNA 1 0.498792