vitiligo Gene Set

Dataset GWASdb SNP-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description A disorder consisting of areas of macular depigmentation, commonly on extensor aspects of extremities, on the face or neck, and in skin folds. Age of onset is often in young adulthood and the condition tends to progress gradually with lesions enlarging and extending until a quiescent state is reached. (Experimental Factor Ontology, EFO_0004208)
External Link http://jjwanglab.org/gwasdb/gwasdb2/gwasdb2/go_trait/HP:0001045
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Genes

68 genes associated with the vitiligo phenotype in GWAS datasets from the GWASdb SNP-Phenotype Associations dataset.

Symbol Name Standardized Value
SLC44A4 solute carrier family 44, member 4 2.55044
BTNL2 butyrophilin-like 2 2.11133
LPP LIM domain containing preferred translocation partner in lipoma 1.93967
TYR tyrosinase 1.88591
ATXN2 ataxin 2 1.87101
C1QTNF6 C1q and tumor necrosis factor related protein 6 1.83117
RNASET2 ribonuclease T2 1.81736
RERE arginine-glutamic acid dipeptide (RE) repeats 1.69824
IKZF4 IKAROS family zinc finger 4 (Eos) 1.66286
IL2RA interleukin 2 receptor, alpha 1.65014
FANCA Fanconi anemia, complementation group A 1.61591
RPGRIP1L RPGRIP1-like 1.57861
UBASH3A ubiquitin associated and SH3 domain containing A 1.52467
NOTCH4 notch 4 1.4821
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 1.43178
TNXB tenascin XB 1.42091
AGPAT1 1-acylglycerol-3-phosphate O-acyltransferase 1 1.39317
EGFL8 EGF-like-domain, multiple 8 1.38278
DDX39B DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B 1.38205
RNF5 ring finger protein 5, E3 ubiquitin protein ligase 1.38047
SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2 1.32793
GTF2H4 general transcription factor IIH, polypeptide 4, 52kDa 1.32379
CCHCR1 coiled-coil alpha-helical rod protein 1 1.32286
ATAT1 alpha tubulin acetyltransferase 1 1.28174
DPCR1 diffuse panbronchiolitis critical region 1 1.27871
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) 1.27708
POU5F1 POU class 5 homeobox 1 1.26433
HCG22 HLA complex group 22 1.25819
PSORS1C3 psoriasis susceptibility 1 candidate 3 (non-protein coding) 1.24979
TRIM15 tripartite motif containing 15 1.23829
TRIM31 tripartite motif containing 31 1.23704
TG thyroglobulin 1.21853
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2 1.19958
CASP7 caspase 7, apoptosis-related cysteine peptidase 1.18704
HERC2 HECT and RLD domain containing E3 ubiquitin protein ligase 2 1.18704
TRIM26 tripartite motif containing 26 1.18447
NEU1 sialidase 1 (lysosomal sialidase) 1.18418
FOXP1 forkhead box P1 1.17979
SMOC2 SPARC related modular calcium binding 2 1.15743
TICAM1 toll-like receptor adaptor molecule 1 1.15743
APOE apolipoprotein E 1.13234
ZMIZ1 zinc finger, MIZ-type containing 1 1.05869
NXPH1 neurexophilin 1 0.976371
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1 0.969142
NEK6 NIMA-related kinase 6 0.940934
SH2B3 SH2B adaptor protein 3 0.939894
ICA1 islet cell autoantigen 1, 69kDa 0.926745
TOMM40 translocase of outer mitochondrial membrane 40 homolog (yeast) 0.911279
UBE2E2 ubiquitin-conjugating enzyme E2E 2 0.858001
CNTN4 contactin 4 0.802296
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator 0.793451
CIB4 calcium and integrin binding family member 4 0.760868
ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 0.74997
SRBD1 S1 RNA binding domain 1 0.733655
DOK6 docking protein 6 0.717203
PHLDB2 pleckstrin homology-like domain, family B, member 2 0.679979
GABRB1 gamma-aminobutyric acid (GABA) A receptor, beta 1 0.676917
DSC3 desmocollin 3 0.661549
CLYBL citrate lyase beta like 0.643425
PRH1-PRR4 PRH1-PRR4 readthrough 0.62426
SORCS1 sortilin-related VPS10 domain containing receptor 1 0.617083
DOCK4 dedicator of cytokinesis 4 0.611597
GHSR growth hormone secretagogue receptor 0.593113
CSMD1 CUB and Sushi multiple domains 1 0.582578
FAM69C family with sequence similarity 69, member C 0.580796
NCS1 neuronal calcium sensor 1 0.557335
IFIH1 interferon induced with helicase C domain 1 0.508244
ZNRD1-AS1 ZNRD1 antisense RNA 1 0.498792