vitiligo Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description A disorder consisting of areas of macular depigmentation, commonly on extensor aspects of extremities, on the face or neck, and in skin folds. Age of onset is often in young adulthood and the condition tends to progress gradually with lesions enlarging and extending until a quiescent state is reached. (Experimental Factor Ontology, EFO_0004208)
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Genes

108 genes co-occuring with the biological term vitiligo in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ACE angiotensin I converting enzyme
ACHE acetylcholinesterase (Yt blood group)
AIRE autoimmune regulator
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1
ARNT aryl hydrocarbon receptor nuclear translocator
BCHE butyrylcholinesterase
C12ORF10 chromosome 12 open reading frame 10
CAT catalase
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CD4 CD4 molecule
CDK5RAP1 CDK5 regulatory subunit associated protein 1
COMT catechol-O-methyltransferase
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CXCL8 chemokine (C-X-C motif) ligand 8
CXCL9 chemokine (C-X-C motif) ligand 9
DCT dopachrome tautomerase
DDR1 discoidin domain receptor tyrosine kinase 1
DKK1 dickkopf WNT signaling pathway inhibitor 1
EDN1 endothelin 1
EDNRA endothelin receptor type A
EDNRB endothelin receptor type B
ESR1 estrogen receptor 1
F2RL1 coagulation factor II (thrombin) receptor-like 1
FAS Fas cell surface death receptor
FBXO11 F-box protein 11
FOXO3 forkhead box O3
FOXP1 forkhead box P1
FOXP3 forkhead box P3
FRS2 fibroblast growth factor receptor substrate 2
FURIN furin (paired basic amino acid cleaving enzyme)
GPX1 glutathione peroxidase 1
GSTM1 glutathione S-transferase mu 1
GSTP1 glutathione S-transferase pi 1
GSTT1 glutathione S-transferase theta 1
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
HLA-A major histocompatibility complex, class I, A
HLA-B major histocompatibility complex, class I, B
HLA-C major histocompatibility complex, class I, C
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HLA-DRB4 major histocompatibility complex, class II, DR beta 4
HLA-G major histocompatibility complex, class I, G
HSPA4 heat shock 70kDa protein 4
IDDM8 insulin-dependent diabetes mellitus 8
IFI30 interferon, gamma-inducible protein 30
IFNE interferon, epsilon
IFNG interferon, gamma
IL10 interleukin 10
IL17A interleukin 17A
IL19 interleukin 19
IL1RN interleukin 1 receptor antagonist
IL2RA interleukin 2 receptor, alpha
IL4 interleukin 4
IL6 interleukin 6
IS1 Adolescent idiopathic scoliosis
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
LTA lymphotoxin alpha
MBL2 mannose-binding lectin (protein C) 2, soluble
MCHR1 melanin-concentrating hormone receptor 1
MIA melanoma inhibitory activity
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MIR196A2 microRNA 196a-2
MLANA melan-A
MSRA methionine sulfoxide reductase A
MSRB2 methionine sulfoxide reductase B2
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MX1 MX dynamin-like GTPase 1
NFE2L2 nuclear factor, erythroid 2-like 2
NLRP1 NLR family, pyrin domain containing 1
NOS2 nitric oxide synthase 2, inducible
NOTCH1 notch 1
NOV nephroblastoma overexpressed
NR1H3 nuclear receptor subfamily 1, group H, member 3
OPRL1 opiate receptor-like 1
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PMCH pro-melanin-concentrating hormone
PMEL premelanosome protein
PNOC prepronociceptin
POMC proopiomelanocortin
PON1 paraoxonase 1
PRO2268 uncharacterized protein PRO2268
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
RNASET2 ribonuclease T2
SIAE sialic acid acetylesterase
SIRT1 sirtuin 1
SMOC2 SPARC related modular calcium binding 2
SOD3 superoxide dismutase 3, extracellular
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TGFB1 transforming growth factor, beta 1
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TH tyrosine hydroxylase
TLR2 toll-like receptor 2
TLR4 toll-like receptor 4
TNF tumor necrosis factor
TP53 tumor protein p53
TRAF2 TNF receptor-associated factor 2
TSLP thymic stromal lymphopoietin
TXNDC5 thioredoxin domain containing 5 (endoplasmic reticulum)
TYR tyrosinase
TYRP1 tyrosinase-related protein 1
UVRAG UV radiation resistance associated
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
XBP1 X-box binding protein 1