vldlr Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description very low density lipoprotein receptor|The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. This gene encodes a lipoprotein receptor that is a member of the LDLR family and plays important roles in VLDL-triglyceride metabolism and the reelin signaling pathway. Mutations in this gene cause VLDLR-associated cerebellar hypoplasia. Alternative splicing generates multiple transcript variants encoding distinct isoforms for this gene. [provided by RefSeq, Aug 2009] (NCBI Entrez Gene Database, 7436)
Similar Terms
Downloads & Tools

Genes

22 genes co-occuring with the biological term vldlr in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
APOC1 apolipoprotein C-I
APOE apolipoprotein E
ARG1 arginase 1
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
DAB1 Dab, reelin signal transducer, homolog 1 (Drosophila)
F8 coagulation factor VIII, procoagulant component
HIC1 hypermethylated in cancer 1
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
LDLR low density lipoprotein receptor
LRP1 low density lipoprotein receptor-related protein 1
LRP6 low density lipoprotein receptor-related protein 6
LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
MIR23B microRNA 23b
PCSK9 proprotein convertase subtilisin/kexin type 9
RELN reelin
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
STX5 syntaxin 5
THBS2 thrombospondin 2
VEGFA vascular endothelial growth factor A
VLDLR very low density lipoprotein receptor